Sang Hyun Lee

ORCID: 0000-0003-2053-4408
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About
Contact & Profiles
Research Areas
  • Anesthesia and Sedative Agents
  • Anesthesia and Pain Management
  • Tracheal and airway disorders
  • Organ Transplantation Techniques and Outcomes
  • Anesthesia and Neurotoxicity Research
  • Airway Management and Intubation Techniques
  • Cardiac, Anesthesia and Surgical Outcomes
  • Aortic aneurysm repair treatments
  • Obstructive Sleep Apnea Research
  • Transplantation: Methods and Outcomes
  • Intensive Care Unit Cognitive Disorders
  • Coronary Interventions and Diagnostics
  • Esophageal and GI Pathology
  • Cardiac Imaging and Diagnostics
  • Nausea and vomiting management
  • Respiratory Support and Mechanisms
  • Liver Disease and Transplantation
  • Enhanced Recovery After Surgery
  • Neurosurgical Procedures and Complications
  • Pain Management and Opioid Use
  • Cardiac Valve Diseases and Treatments
  • Vascular Anomalies and Treatments
  • Blood transfusion and management
  • Cardiac Arrest and Resuscitation
  • Cardiac Ischemia and Reperfusion

Pusan National University Yangsan Hospital
2019-2025

Samsung Medical Center
2014-2024

Sungkyunkwan University
2014-2024

Seoul National University
1985-2024

Dong-A University Hospital
2023

Pusan National University Hospital
2019-2021

Inje University
2014-2020

Novem (Netherlands)
2019

Kangwon National University
2019

National Cancer Center
2010-2018

Driving pressure (plateau minus end-expiratory airway pressure) is a target in patients with acute respiratory distress syndrome, and proposed as during general anesthesia for normal lungs. It has not been reported thoracic where isolated, inflated lungs may be especially at risk.In double-blinded, randomized trial (292 patients), minimized driving compared standard protective ventilation was associated less postoperative pneumonia or syndrome.Recently, several retrospective studies have...

10.1097/aln.0000000000002600 article EN Anesthesiology 2019-01-24

10.1016/j.molcel.2007.11.036 article EN publisher-specific-oa Molecular Cell 2008-02-01

Influenza, one of the most contagious and infectious diseases, is predominantly transmitted through aerosols, leading to development filter-based protective equipment. Though currently available filters are effective at removing submicron-sized particulates, filter materials with enhanced virus-capture efficiency still in demand. Coating or chemically modifying molecules capable binding influenza viruses has received attention as a promising approach for production virus-capturing filters....

10.1038/s41598-020-78929-4 article EN cc-by Scientific Reports 2021-01-13

In Brief BACKGROUND: There have been inconsistent reports on whether opioids promote or inhibit lung cancer growth. this study, we suggest that opioid growth factor receptor (OGFR), a negative regulator of cell proliferation, is binding site morphine and involved in subsequent morphine-induced suppression. METHODS: The expression distribution OGFR human tissues lines were assessed with immunohistochemistry real-time reverse transcription polymerase chain reaction. line, H1975...

10.1213/ane.0000000000001293 article EN Anesthesia & Analgesia 2016-05-12

Postoperative analgesia and care for living liver donors have become particular interests clinicians as the use of donor transplantation has increased. Local anesthetic-based been known to provide effective pain control. In this prospective, randomized study, we compared postoperative analgesic efficacy local (PainBuster) with opioid-based [intrathecal morphine (ITM) intravenous (IV) fentanyl] in donors. Forty adult were randomly allocated 1 2 groups: an ITM/IV fentanyl group (n = 21) a...

10.1002/lt.23691 article EN Liver Transplantation 2013-06-21

Background Cryoprecipitate may be used to treat bleeding in cardiac surgery. Its effects on plasma fibrinogen and fibrin clotting this setting are poorly defined. Study Design And Methods Patients undergoing on‐pump aortic surgery with deep hypothermic circulatory arrest ( DHCA ) were recruited prospectively. After protamine reversal, cryoprecipitate was administered patients bleeding, deficit indicated by thromboelastometry ROTEM )‐based FIBTEM test. Coagulation assessed using ‐based tests...

10.1111/trf.12479 article EN Transfusion 2013-11-05

To investigate the association between treatment with an angiotensin receptor blocker and clinical outcomes in patients ST segment elevation myocardial infarction preserved left ventricular systolic function.A prospective cohort study using data from a nationwide large scale registry.53 hospitals involved of acute Korea.Between November 2005 September 2010, we studied 6698 who underwent primary percutaneous coronary intervention had ejection fraction ≥ 40%.Cardiac death or infarction....

10.1136/bmj.g6650 article EN cc-by-nc BMJ 2014-11-14

An undeflatable stent balloon following its inflation during percutaneous coronary intervention (PCI) is a rare and unpredictable complication that can lead to serious consequences. Currently, there no standardized protocol for managing this issue. 83-year-old man presented with chest pain. Coronary angiography showed chronic total occlusion (CTO)-like lesion in the proximal left anterior descending artery (LAD). Following deployment, failed deflate remained inflated within LAD. Despite...

10.3389/fcvm.2025.1565014 article EN cc-by Frontiers in Cardiovascular Medicine 2025-03-17

Despite expanding demands for non-operating room anesthesia (NORA) worldwide, studies in this field are scarce. We compared the overall characteristics and nature of deaths occurring within 48 hours after surgery between NORA operating (ORA) cases at a Korean tertiary hospital. retrospectively analyzed medical records patients who underwent surgical procedures under services outside from January 2013 to November 2017. All mortalities were categorized by principal cause into groups such as...

10.3346/jkms.2018.33.e183 article EN cc-by-nc Journal of Korean Medical Science 2018-01-01

Purpose: Open infrarenal abdominal aortic aneurysm (AAA) repair is performed without event in most cases.However, some patients suffer major morbidities such as renal failure, myocardial infarction, paraplegia, acute respiratory distress syndrome, or hepatic dysfunction.Predicting what kinds of patient populations are more prone to develop complications may keep the clinicians attentive patients, possibly leading better prognoses.In this retrospective study, we searched incidence and risk...

10.3349/ymj.2011.52.2.339 article EN cc-by-nc Yonsei Medical Journal 2011-01-01

We aimed to assess the predictive value of fibrin-based thromboelastometry performed before weaning from cardiopulmonary bypass (CPB) for cryoprecipitate administered correct bleeding diathesis after CPB involving deep hypothermic circulatory arrest. Eleven patients undergoing aortic surgery were enrolled. The arterial blood was withdrawn skin incision, 30 min (Cweaning), 5 protamine reversal (Preversal) and at closure sternum run intrinsically activated INTEM, heparinase-treated HEPTEM,...

10.1097/mbc.0b013e32833e4228 article EN Blood Coagulation & Fibrinolysis 2010-08-20

Background There is a need for investigating the analgesic method as part of early recovery after surgery tailored laparoscopic colorectal cancer (LCRC) surgery. In this randomized trial, we aimed to investigate efficacy an inverse 'v' shaped bilateral, subfascial ropivacaine continuous infusion in LCRC Methods Forty two patients undergoing elective were randomly allocated one groups receive either 0.5% at plane (n = 20, R group) or fentanyl intravenous patient controlled analgesia (IV PCA)...

10.4097/kjae.2016.69.6.604 article EN cc-by-nc Korean journal of anesthesiology 2016-01-01

This study aimed to evaluate whether dihydroferulic acid (dFA) promoted the viability of H2O2-treated PC12 cells and functional recovery from ischemic injury. The animals were divided into four groups for study: (1) vehicle treated (saline, 1 mL/kg), (2) dFA 5 mg/kg treated, (3) dFA10 (4) 20 groups. Neurological deficit was evaluated using modified neurological severity score. Real-time polymerase chain reaction analyses performed with protein disulphide isomerase (PDI), nuclear...

10.1590/fst.33719 article EN Food Science and Technology 2020-06-01

Abstract Although the varied neurotoxicity of intrathecal ( IT ) chemotherapy for treatment childhood acute leukemia is well known, most are related to transient post‐puncture headache, drug‐induced arachnoiditis, or leukoencephalopathy after methotrexate cytarabine. Cerebral vasospasm leading infarct very uncommon in children. Reported herein a rare case diffuse cerebral with subsequent cytarabine 7‐year‐old boy lymphoblastic leukemia, who successfully recovered supportive management, and...

10.1111/ped.12394 article EN Pediatrics International 2014-12-01

Cerebral ischemia is clinically characterized by a partial functional neurological deficit, which represents one of the leading causes death. This study aimed to determine whether rice bran extract (RB), ferulic acid (FA), or supplemented with FA (RB + FA) promote recovery from ischemic injury. Focal cerebral was induced middle artery occlusion (MCAO) in rats. Four groups were studied, including (1) vehicle group, (2) RB 5%, 10%, and 20% groups, (3) (4) group. Animals injected once day for 3...

10.1080/19768354.2014.904249 article EN Animal Cells and Systems 2014-03-04

Caudal epidural injection is a common intervention in patients with low back pain and sciatica. Even though the complications of fluoroscopically directed injections are less frequent than blind injections, due to contrast media can occur. We report case anaphylactic shock immediately after an intravenous nonionic medium (iohexol) during caudal for sciatica patient without previous allergic history ionic (ioxitalamate). Five minutes dye was injected, began experience dizziness, systolic...

10.3344/kjp.2015.28.4.280 article EN cc-by-nc The Korean journal of pain 2015-10-15
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