A5024932707- Cardiac Imaging and Diagnostics
- Coronary Interventions and Diagnostics
- Acute Myocardial Infarction Research
- Advanced Radiotherapy Techniques
- Atrial Fibrillation Management and Outcomes
- Radiation Dose and Imaging
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac Arrhythmias and Treatments
- Cardiac Ischemia and Reperfusion
- Radiation Therapy and Dosimetry
- Advanced X-ray and CT Imaging
- Cardiac electrophysiology and arrhythmias
- Blood Pressure and Hypertension Studies
- Venous Thromboembolism Diagnosis and Management
- Cardiac Structural Anomalies and Repair
- Cardiac pacing and defibrillation studies
- Lipoproteins and Cardiovascular Health
- Cardiac Arrest and Resuscitation
- Cardiac Valve Diseases and Treatments
- Mechanical Circulatory Support Devices
- Cardiovascular Function and Risk Factors
- Coronary Artery Anomalies
- Heart Failure Treatment and Management
- Cardiac tumors and thrombi
- Hormonal Regulation and Hypertension
Pusan National University Yangsan Hospital
2016-2025
Pusan National University
2004-2025
Daewoong Pharmaceutical (South Korea)
2025
Sejong University
2017-2023
Korea University
2017-2023
Seoul National University Hospital
2022
Korea Research Institute of Standards and Science
2006-2016
Korea University of Science and Technology
2016
Pusan National University Hospital
2004-2015
Krankenhaus Bethanien
2014
Data regarding clinical outcomes after intravascular imaging–guided percutaneous coronary intervention (PCI) for complex coronary-artery lesions, as compared with angiography-guided PCI, are limited. Download a PDF of the Research Summary. In this prospective, multicenter, open-label trial in South Korea, we randomly assigned patients lesions 2:1 ratio to undergo either PCI or PCI. imaging group, choice between ultrasonography and optical coherence tomography was at operators' discretion....
The RENOVATE-COMPLEX-PCI (Randomized Controlled Trial of Intravascular Imaging Guidance Versus Angiography-Guidance on Clinical Outcomes After Complex Percutaneous Coronary Intervention) demonstrated that intravascular imaging-guided percutaneous coronary intervention (PCI) improved clinical outcome compared with angiography-guided PCI for patients complex artery lesions. This study aims to assess whether the prognostic benefit procedural optimization persists in undergoing left main disease.
Abstract The aim of this study was to assess the accuracy and stability frameless gamma knife radiosurgery ( GKRS ). accuracies radiation isocenter patient couch movement were evaluated by film dosimetry with a half‐year cycle. Radiation assessment diode detector cone‐beam computed tomography CBCT ) image tests performed daily vendor‐provided tool for one half years after installation. quality examined twice month phantom. coregistration using images studied magnetic resonance MR CT another...
Background and objectives Large clinical studies of sodium/glucose cotransporter 2 (SGLT2) inhibitors have shown a significant beneficial effect on heart failure-associated hospitalization cardiovascular events. As SGLT2 is known to be absent in cells, improved outcomes are thought accounted for by the indirect effects drug. We sought confirm whether such benefits were mediated through expressed using myocardial infarction (MI) model. Methods Mice pre-treated with empagliflozin (EMPA), an...
Influenza A virus (IAV) is a major cause of respiratory infections worldwide. Current preventive measures, though effective for decades, face limitations due to the continuous evolution viral strains and challenges in targeting specific proteins. In this study, we conducted vivo screenings evaluate antiviral properties various promising polymers overcome current infection prevention strategies. Subsequently, performed detailed physiological pathological assessments over an extended period....
Percutaneous coronary intervention (PCI) through the aorto-ostial stent that is protruding into aorta remains a technical challenge because of poor coaxial alignment guiding catheter and inability to advance guidewire distal vessel stent's central lumen. In this article, we introduce dual-lumen microcatheter-facilitated wiring technique performed on two patients overcome difficulty. The first case was 75-year-old man who presented with chest pain. He diagnosed an unstable angina, angiography...
An undeflatable stent balloon following its inflation during percutaneous coronary intervention (PCI) is a rare and unpredictable complication that can lead to serious consequences. Currently, there no standardized protocol for managing this issue. 83-year-old man presented with chest pain. Coronary angiography showed chronic total occlusion (CTO)-like lesion in the proximal left anterior descending artery (LAD). Following deployment, failed deflate remained inflated within LAD. Despite...
In the original publication [...]
Background Intravenous nicorandil infusion with percutaneous coronary intervention (PCI) has been reported to reduce reperfusion injury events and improve cardiac function in patients acute myocardial infarction (MI). However, there is limited information on the use of intracoronary nicorandil. Methods Results In present study, 73 ST segment elevation MI undergoing PCI were randomly assigned Nicorandil Group (n=37) or Control (n=36). The composite endpoints incidences ventricular arrhythmia,...
De-escalation of dual-antiplatelet therapy through dose reduction prasugrel improved net adverse clinical events after acute coronary syndrome (ACS), mainly the bleeding without an increase in ischemic outcomes. However, whether such benefits are similarly observed those receiving complex procedures is unknown.To investigate de-escalation maintained percutaneous intervention (PCI) subgroup.This was a post hoc analysis HOST-REDUCE-POLYTECH-ACS trial, randomized, open-label,...
Importance Data are limited regarding the effects of intravascular imaging guidance during complex percutaneous coronary intervention (PCI) in patients with diabetes. Objective To compare clinical outcomes imaging–guided vs angiography-guided PCI or without Design, Setting, and Participants This prespecified secondary analysis a subgroup RENOVATE-COMPLEX-PCI (Randomized Controlled Trial Intravascular Imaging Guidance Versus Angiography-Guidance on Clinical Outcomes After Complex Percutaneous...
Image co-registration is used in frameless gamma knife radiosurgery (GKSRS) to assign a stereotactic coordinate system and verify patient setup before irradiation. The accuracy of with cone beam computed tomography (CBCT) images Gamma Knife IconTM (GK Icon) was assessed, the effects region (ROC) were studied. CBCT-to-CBCT for verification, its examined by co-registering CBCT taken at various configurations reference series. assignment investigated CT configurations. An anthropomorphic...
Both the beneficial relationship between exercise and quality of life important role played by self-efficacy in maintaining an regimen among individuals with chronic heart failure are well known. However, most nursing interventions for Korean patients focus only on providing education related to risk factors symptoms. Little information is available regarding influence physical functions, activity, life.This study was conducted examine impact functioning, failure.This used a cross-sectional...
Recently, approximately 40% of all heart transplantation (HTx) in South Korea are performed using the direct extracorporeal membrane oxygenation (ECMO) bridging method. We conducted a study to examine clinical outcome ECMO-bridged HTx and investigate impact multi-organ failure (MOF).From June 2014 September 2022, total 96 adult patients who underwent isolated at single tertiary hospital were included study. The sub-grouped into ECMO (n=48) non-ECMO group (n=48), was subdivided awake (n=22)...
Background It is generally accepted that morphine affords cardioprotection against ischemia/reperfusion injury. Inhibition of the mitochondrial permeability transition pore (MPTP) considered an end target for cardioprotection. The aim this study was to investigate involvement opioid receptors (OR) and MPTP in morphine-induced postconditioning (M-Post). Methods Isolated rat hearts were subjected 30 min regional ischemia 2 h reperfusion. Hearts treated with 1 µM morphine, or without OR...
Coronary CT angiography (CCTA) allows accurate evaluation of coronary artery stenosis but has limitations in information on hemodynamic significance stenotic lesions.To determine the feasibility adenosine-stress low-dose single-scan myocardial perfusion imaging (MPI) using a 128-slice dual-source scanner for diagnosis hemodynamically significant as defined by fractional flow reserve (FFR).This study was proved Institutional Review Board and informed consent obtained from patients before...
We compared the efficacy and safety of valsartan rosuvastatin combination therapy with each treatment alone in hypercholesterolemic hypertensive patients.Patients who met inclusion criteria were randomized to receive 1 following 2-month drug regimens: 160 mg plus 20 mg, placebo, or placebo. The primary variables change sitting diastolic blood pressure (sitDBP) systolic (sitSBP), percentage low-density lipoprotein-cholesterol (LDL-C) combination, valsartan, groups. Adverse events (AEs) during...
Importance There have been heterogeneous results related to sex differences in prognosis after percutaneous coronary artery intervention (PCI) for complex lesions. Objective To evaluate potential outcomes with intravascular imaging–guided PCI of lesions between women and men. Design, Setting, Participants This prespecified substudy evaluates the interaction investigator-initiated, open-label, multicenter RENOVATE-COMPLEX-PCI randomized clinical trial, which demonstrated superiority compared...
Background Cilostazol has a vasodilatory function that may be beneficial for patients with vasospastic angina (VSA). We conducted randomized, open-label, controlled trial to compare the efficacy and safety of long-acting cilostazol isosorbide mononitrate (ISMN) VSA. Methods The study included confirmed VSA between September 2019 May 2021. Participants were randomly assigned receive (test group, 200 mg once daily) or conventional ISMN therapy (control 20 twice 4 weeks. clinical evaluated...
Background In the general population, incidence of bundle branch block (BBB) is relatively low, and its effects on long-term prognosis have not been established. Previous studies correlation BBB to clinical factors produced conflicting results. However, was strongly related age. This study aimed describe risk for in Korea. Methods this study, 14,540 adults (male 6,573/female 7,967) ≥40 years old received screening tests health between April December 2000. Participants answered questionnaires...