A5011628126- Cardiac Imaging and Diagnostics
- Cardiovascular Function and Risk Factors
- Coronary Interventions and Diagnostics
- Acute Myocardial Infarction Research
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiovascular Disease and Adiposity
- Cardiovascular Health and Disease Prevention
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Cerebrovascular and Carotid Artery Diseases
- Atrial Fibrillation Management and Outcomes
- Lipoproteins and Cardiovascular Health
- Peripheral Artery Disease Management
- Advanced Glycation End Products research
- Blood Pressure and Hypertension Studies
- Liver Disease Diagnosis and Treatment
- Cardiac Valve Diseases and Treatments
- Acute Ischemic Stroke Management
- Cardiac Arrhythmias and Treatments
- Cardiac Structural Anomalies and Repair
- Gout, Hyperuricemia, Uric Acid
- Inflammasome and immune disorders
- Nosocomial Infections in ICU
- Folate and B Vitamins Research
- Vascular anomalies and interventions
- Metastasis and carcinoma case studies
Chung-Ang University
2023-2024
Chung-Ang University Hospital
2024
Keimyung University
2015-2023
Ulsan College
2016-2023
University of Ulsan
2016-2023
Ulsan University Hospital
2016-2023
Dongguk University Ilsan Hospital
2022-2023
Yonsei University Health System
2018-2023
Keimyung University Dongsan Medical Center
2016-2023
Yonsei University
2012-2022
Data on the relationship between triglyceride glucose (TyG) index and coronary artery calcification (CAC) progression is limited. This longitudinal study evaluated association of TyG with CAC in asymptomatic adults.We enrolled 12,326 Korean adults who had at least two evaluations. The was determined using ln (fasting triglycerides [mg/dL] × fasting [mg/dL]/2). defined as a difference ≥ 2.5 square roots (√) baseline follow-up calcium score (CACS) (Δ√transformed CACS). Annualized Δ√transformed...
Abstract This study evaluated the relationship of insulin resistance (IR) and glycemic control status to presence severity coronary artery disease (CAD) according diabetes. The IR parameters including homeostatic model assessment (HOMA-IR), triglyceride-glucose (TyG) index, triglyceride-to-high density lipoprotein cholesterol ratio (TG/HDL), hemoglobin A1C (HbA1C) level CAD obstructive was in 5,764 asymptomatic subjects who underwent computed tomographic angiography. Non-diabetics (n = 4768)...
Insulin resistance (IR) is an important risk factor for subclinical atherosclerosis. This study evaluated the relationship between triglyceride glucose (TyG) index, which a simple and reliable surrogate marker IR, arterial stiffness.This included 2560 Korean subjects without previous history of coronary artery disease, stroke, malignancies who participated in community-based cohort study. Arterial stiffness was measured using brachial-ankle pulse wave velocity (baPWV).All participants were...
Atherosclerotic cardiovascular (CV) events commonly occur in individuals with a low CV risk burden. This study evaluated the ability of triglyceride glucose (TyG) index to predict subclinical coronary artery disease (CAD) asymptomatic subjects without traditional factors (CVRFs).This retrospective, cross-sectional, and observational association TyG CAD 1250 (52.8 ± 6.5 years, 46.9% male) CVRFs (defined as systolic/diastolic blood pressure ≥ 140/90 mmHg; fasting ≥126 mg/dL; total cholesterol...
The association between triglyceride glucose (TyG) index and coronary atherosclerotic change remains unclear. We aimed to evaluate the TyG plaque progression (PP) using serial computed tomography angiography (CCTA).A total of 1143 subjects (aged 60.7 ± 9.3 years, 54.6% male) who underwent CCTA with available data on diabetic status were analyzed from Progression AtheRosclerotic PlAque DetermIned by Computed TomoGraphic Angiography IMaging (PARADIGM) registry. PP was defined as volume (PV)...
The triglyceride glucose (TyG) index is a useful surrogate marker for insulin resistance, which an important risk factor coronary artery disease (CAD). However, data on the relationship of TyG and plaque characteristics are limited. This study included 2840 participants with near-normal renal function who underwent computed tomography angiography. CAD was defined as presence any plaques, obstructive plaques ≥50% stenosis. between noncalcified (NCP), calcified or mixed (CMP), calcium score...
Abstract Background Atherogenic lipoprotein profile of plasma is an important risk factor for atherosclerosis. The atherogenic index (AIP) has been suggested as a novel marker Hypothesis AIP useful advanced subclinical coronary artery disease (CAD) in subjects without overt renal dysfunction. Methods A total 6928 with estimated glomerular filtration rate > 60 mL/minutes/1.73 m 2 evaluated by computed tomography angiography (CCTA) health check‐up were included. relation to CAD (heavy...
De-escalation of dual-antiplatelet therapy through dose reduction prasugrel improved net adverse clinical events after acute coronary syndrome (ACS), mainly the bleeding without an increase in ischemic outcomes. However, whether such benefits are similarly observed those receiving complex procedures is unknown.To investigate de-escalation maintained percutaneous intervention (PCI) subgroup.This was a post hoc analysis HOST-REDUCE-POLYTECH-ACS trial, randomized, open-label,...
Abstract This study evaluated the association of atherogenic index plasma (AIP) with platelet reactivity and clinical outcomes according to acute myocardial infarction (AMI). The composite 3-year adverse all-cause death, infarction, cerebrovascular accident was in 10,735 patients after successful percutaneous coronary intervention drug-eluting stents. AIP defined as base 10 logarithm ratio triglyceride high-density lipoprotein cholesterol concentration. High (HPR) ≥ 252 P2Y12 unit. An...
Background:Although the prevalence of both atrial fibrillation (AF) and metabolic syndrome (MetS) has been increasing in East Asia, association between them is uncertain.
Individuals without traditional cardiovascular risk factors (CVRFs) still experience adverse events in clinical practice. This study evaluated the predictors of subclinical coronary atherosclerosis individuals CVRFs.A total 1250 (52.8 ± 6.5 years, 46.9% male) asymptomatic CVRFs who underwent computed tomographic angiography for a general health examination were analysed. The following considered as CVRFs: systolic/diastolic blood pressure ≥140/90 mmHg; fasting glucose ≥126 mg/dL; cholesterol...
Advanced glycation end-products (AGEs) contribute to the development of atherosclerosis. We investigated whether serum AGEs are related presence or severity coronary artery disease (CAD), and explored association between arterial stiffness according diabetes status in patients suspected having CAD.The measurement brachial-ankle pulse wave velocity (baPWV) were performed 145 consecutive (63±9 years, 58% men) who received a angiogram for evaluation CAD.Forty-four diabetics 101 non-diabetics...
Abstract This study aimed to evaluate the association between atherogenic index of plasma (AIP), which has been suggested as a novel marker for atherosclerosis, and coronary artery calcification (CAC) progression according baseline calcium score (CACS). We included 12,326 asymptomatic Korean adults who underwent at least two CAC evaluations from December 2012 August 2016. Participants were stratified into four groups AIP quartiles, determined by log (triglyceride/high-density lipoprotein...
This study aimed to evaluate long-term survival according the presence of metabolic syndrome (MS) in patients with acute myocardial infarction (AMI) undergoing successful percutaneous coronary intervention (PCI) drug-eluting stents (DES).Despite significance reperfusion AMI, prognostic impact MS has been investigated under inconsistent therapy AMI patients.Three-year clinical outcomes, including all-cause death and composite cardiac or infarction, were evaluated status for 963 treated PCI...
Abstract Background After acute myocardial infarction (AMI), the replicated phenomenon of obesity paradox, i.e., appearing to be associated with increased survival, has not been evaluated in stabilized (i.e., without clinical events within 1 month post AMI) Asian patients diabetes mellitus (DM). Methods Among 1192 DIabetic Acute Myocardial InfarctiON Disease (DIAMOND) Korean multicenter registry between April 2010 and June 2012, 2-year cardiac all-cause death were compared according (body...
Metabolic syndrome (MetS) is associated with increased risks of diabetes and atherosclerotic cardiovascular disease. Whether central obesity (CeO) a prerequisite for the diagnosis MetS in International Diabetes Federation (IDF) definition substantial issue because it may influence clinical value predicting subclinical atherosclerosis. We investigated relation between MetS, as defined by National Cholesterol Education Program–Adult Treatment Panel (NCEP–ATP) III criteria, arterial stiffness...
<h3>Objective</h3> Apical hypertrophic cardiomyopathy (HCM) is characterised by apical systolic obliteration and associated with atrial fibrillation (AF), stroke, heart failure (HF), mortality. We investigated whether of the left ventricular (LV) cavity could have an unfavourable impact on clinical course HCM. <h3>Methods</h3> 188 patients HCM (114 males, median age 67 years) were identified retrospectively from January 2008 to December 2010. The rate was defined as net end-diastolic cap...
This study evaluated the association of body mass index (BMI) with adverse clinical outcomes during chronic maintenance antiplatelet monotherapy after percutaneous coronary intervention (PCI) drug-eluting stents (DES).
Objectives Despite an obvious improvement in the treatment of coronary artery disease (CAD) and survival rate patients with CAD during recent decades, diabetes mellitus (DM) is still considered a risk factor adverse clinical outcomes these patients. Therefore, we sought to evaluate implications DM who underwent contemporary percutaneous intervention (PCI). Methods Based on National Health Insurance claims data South Korea, aged 18 years or older had undergone PCI for diagnosis between 2011...