Pedro de Araújo Gonçalves
A5085941737- Cardiac Imaging and Diagnostics
- Coronary Interventions and Diagnostics
- Acute Myocardial Infarction Research
- Cardiac Valve Diseases and Treatments
- Advanced X-ray and CT Imaging
- Cerebrovascular and Carotid Artery Diseases
- Cardiovascular Function and Risk Factors
- Cardiac Arrhythmias and Treatments
- Blood Pressure and Hypertension Studies
- Radiation Dose and Imaging
- Lipoproteins and Cardiovascular Health
- Cardiovascular Disease and Adiposity
- Vascular Procedures and Complications
- Cardiovascular Effects of Exercise
- Cardiac, Anesthesia and Surgical Outcomes
- Infective Endocarditis Diagnosis and Management
- Venous Thromboembolism Diagnosis and Management
- Cardiac pacing and defibrillation studies
- Atrial Fibrillation Management and Outcomes
- Advanced MRI Techniques and Applications
- Vascular anomalies and interventions
- Cardiovascular Health and Disease Prevention
- Coronary Artery Anomalies
- Heart Rate Variability and Autonomic Control
- Antiplatelet Therapy and Cardiovascular Diseases
Hospital da Luz
2016-2025
Hospital de Santa Cruz
2015-2024
Universidade Nova de Lisboa
2014-2024
Inserm
2024
Institut Pasteur
2024
University of Milan
2024
Centro Hospitalar de Lisboa Ocidental
2012-2022
Povisa Hospital
2021-2022
Cornell University
2021-2022
Ludwig-Maximilians-Universität München
2022
Aims Regarding prognosis, patients with a non-ST elevation acute coronary syndrome (ACS) are very heterogeneous population, varying risks of early and long-term adverse events. Early risk stratification at admission seems to be essential for tailored therapeutic strategy. We sought compare the prognostic value three ACS scores (RSs) their ability predict benefit from myocardial revascularization performed during initial hospitalization. Methods results studied 460 consecutive admitted our...
Symptom-based pretest probability scores that estimate the likelihood of obstructive coronary artery disease (CAD) in stable chest pain have moderate accuracy. We sought to develop a machine learning (ML) model, utilizing clinical factors and calcium score (CACS), predict presence CAD on computed tomography angiography (CCTA).
The density of atherosclerotic plaque forms the basis for categorizing calcified and noncalcified morphology plaques.To assess whether alterations in across a range measurements provide more detailed understanding disease progression.This cohort study enrolled 857 patients who underwent serial coronary computed tomography angiography 2 or years apart had quantitative plaques throughout entire artery tree. was conducted from 2013 to 2016 at 13 sites 7 countries.The main outcome progression...
Background— Computed tomography–adapted Leaman score (CT-LeSc) was developed to quantify coronary CT angiography information about atherosclerotic burden (lesion localization, stenosis degree, and plaque composition). The objective of the study is evaluate CT-LeSc long-term prognostic value in patients with suspected artery disease (CAD). Methods Results— Single-center prospective registry including 1304 consecutive undergoing for CAD. High defined by upper tertile (score, >5) cutoff....
<h3>Importance</h3> Plaque morphologic measures on coronary computed tomography angiography (CCTA) have been associated with future acute syndrome (ACS). However, the evolution of calcified plaques by noninvasive imaging is not known. <h3>Objective</h3> To ascertain whether increasing density in plaque risk for ACS. <h3>Design, Setting, and Participants</h3> This multicenter case-control cohort study included individuals enrolled ICONIC (Incident Coronary Syndromes Identified Computed...
Background Rapid coronary plaque progression (RPP) is associated with incident cardiovascular events. To date, no method exists for the identification of individuals at risk RPP a single point in time. This study integrated computed tomography angiography-determined qualitative and quantitative features within machine learning (ML) framework to determine its performance predicting RPP. Methods Results Qualitative angiography characterization was performed 1083 patients who underwent serial...
Renal denervation (RDN) has been shown to lower blood pressure (BP), but its effects on cardiovascular events have only preliminarily evaluated. Time in therapeutic range (TTR) of BP is associated with events. This study sought assess the impact catheter-based RDN TTR and association outcomes GSR (Global SYMPLICITY Registry). Patients uncontrolled hypertension were enrolled treated radiofrequency RDN. Office ambulatory systolic (OSBP ASBP) measured at 3, 6, 12, 24, 36 months postprocedure...
We assessed whether combinations of cardiometabolic risk factors independently predict coronary plaque progression (PP) and major adverse cardiovascular events in patients with stable artery disease.
Abstract Aims In patients without obstructive coronary artery disease (CAD), we examined the prognostic value of risk factors and atherosclerotic extent. Methods results Patients from long-term CONFIRM registry prior CAD (≥50%) stenosis were included. Within groups normal computed tomography angiography (CCTA) (N = 1849) non-obstructive 1698), traditional clinical extent (segment involvement score, SIS) was assessed with Cox models. Major adverse cardiac events (MACE) defined as all-cause...
Abstract Shotgun lipidomic analysis of 203 lipids in 13 lipid classes performed on blood plasma donors who had just suffered an acute coronary syndrome (ACS, n = 74), or ischemic stroke (IS, 21), suffer from stable angina pectoris (SAP, 78), and age-matched control cohort ( 52), showed some the highest inter-lipid class correlations between cholesteryl esters (CE) phosphatidylcholines (PC) sharing a common fatty acid. The concentration lysophospatidylcholine (LPC) ratios concentrations CE to...
The association between triglyceride glucose (TyG) index and coronary atherosclerotic change remains unclear. We aimed to evaluate the TyG plaque progression (PP) using serial computed tomography angiography (CCTA).A total of 1143 subjects (aged 60.7 ± 9.3 years, 54.6% male) who underwent CCTA with available data on diabetic status were analyzed from Progression AtheRosclerotic PlAque DetermIned by Computed TomoGraphic Angiography IMaging (PARADIGM) registry. PP was defined as volume (PV)...
Abstract Aims High-risk plaque (HRP) and non-obstructive coronary artery disease independently predict adverse events, but their importance to future culprit lesions has not been resolved. We sought determine in patients prior confirmed acute syndrome (ACS) the association between lesion percent diameter stenosis (%DS), absolute number prevalence of HRP. The secondary objective was examine relative HRP lesions. Methods results Within ICONIC study, a nested case–control study undergoing...
Distinct plaque locations and vessel geometric features predispose to altered coronary flow hemodynamics. The association between these lesion-level characteristics assessed by computed tomographic angiography (CCTA) risk of future acute syndrome (ACS) is unknown.To examine whether CCTA-derived adverse (AGCs) lesions describing location geometry add morphology burden for identifying culprit lesion precursors associated with ACS.This substudy ICONIC (Incident Coronary Syndromes Identified...
<h3>Importance</h3> Several studies have reported that the progression of coronary atherosclerosis, as measured by serial computed tomographic (CT) angiography, is associated with risk future cardiovascular events. However, cumulative consequences multiple factors for plaque and development adverse characteristics not been well characterized. <h3>Objectives</h3> To examine association factor burden, assessed atherosclerotic disease (ASCVD) score, atherosclerosis characteristics. <h3>Design,...
Abstract Aims The totality of atherosclerotic plaque derived from coronary computed tomography angiography (CCTA) emerges as a comprehensive measure to assess the intensity medical treatment that patients need. This study examines differences in age onset and prognostic significance burden between sexes. Methods results From large multi-center CCTA registry Leiden score was calculated 24 950 individuals. A total 11 678 women (58.5 ± 12.4 years) 13 272 men (55.6 12.5 were followed for 3.7...