- Cardiac Imaging and Diagnostics
- Coronary Interventions and Diagnostics
- Acute Myocardial Infarction Research
- Advanced X-ray and CT Imaging
- Radiation Dose and Imaging
- Cardiovascular Function and Risk Factors
- Advanced MRI Techniques and Applications
- Cardiovascular Disease and Adiposity
- Cerebrovascular and Carotid Artery Diseases
- Ultrasound in Clinical Applications
- Lipoproteins and Cardiovascular Health
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac Valve Diseases and Treatments
- Medical Imaging Techniques and Applications
- Cardiac Arrhythmias and Treatments
- Cardiac electrophysiology and arrhythmias
- Aortic Thrombus and Embolism
- Radiology practices and education
- Atrial Fibrillation Management and Outcomes
- Atherosclerosis and Cardiovascular Diseases
- Coronary Artery Anomalies
- Advanced Radiotherapy Techniques
- Brain Metastases and Treatment
- Infective Endocarditis Diagnosis and Management
- Venous Thromboembolism Diagnosis and Management
Beaumont Hospital, Royal Oak
2014-2023
Oakland University
2015-2020
Beaumont Health
2009-2020
Beaumont Hospital, Troy
2009-2020
Emory University
2017-2020
CVPath Institute
2020
New York Hospital Queens
2018-2019
NewYork–Presbyterian Hospital
2017-2019
Cornell University
2011-2019
Weill Cornell Medicine
2018-2019
Traditional prognostic risk assessment in patients undergoing non-invasive imaging is based upon a limited selection of clinical and findings. Machine learning (ML) can consider greater number complexity variables. Therefore, we investigated the feasibility accuracy ML to predict 5-year all-cause mortality (ACM) coronary computed tomographic angiography (CCTA), compared performance existing or CCTA metrics. The analysis included 10 030 with suspected artery disease follow-up from COronary CT...
Background— Guidelines for the management of patients with suspected coronary artery disease (CAD) rely on age, sex, and angina typicality–based pretest probabilities angiographically significant CAD derived from invasive angiography (guideline probabilities). Reliability guideline has not been investigated in referred to noninvasive testing. Methods Results— We identified 14048 consecutive who underwent computed tomographic angiography. Angina typicality was recorded use accepted criteria....
The 1-year data from the international ADVANCE (Assessing Diagnostic Value of Non-invasive FFRCT in Coronary Care) Registry patients undergoing coronary computed tomography angiography (CTA) was used to evaluate relationship fractional flow reserve derived CTA (FFRCT) with downstream care and clinical outcomes.Guidelines for management chest pain using noninvasive imaging pathways are based on short- intermediate-term outcomes.Patients (N = 5,083) evaluated clinically suspected artery...
Non-invasive assessment of stable chest pain patients is a critical determinant resource utilization and clinical outcomes. Increasingly coronary computed tomography angiography (CCTA) with selective CCTA-derived fractional flow reserve (FFRCT) being used. The ADVANCE Registry, large prospective examination using CCTA FFRCT diagnostic pathway in real-world settings, the aim determining impact this on decision-making, downstream invasive (ICA), revascularization, major adverse cardiovascular...
Symptom-based pretest probability scores that estimate the likelihood of obstructive coronary artery disease (CAD) in stable chest pain have moderate accuracy. We sought to develop a machine learning (ML) model, utilizing clinical factors and calcium score (CACS), predict presence CAD on computed tomography angiography (CCTA).
Cardiac computed tomography angiography (CCTA) can accurately diagnose coronary artery disease, but radiation dose from this procedure is of concern.To determine whether a collaborative dose-reduction program would be associated with reduced in patients undergoing CCTA statewide registry over 1-year period and to define its effect on image quality.A prospective, controlled, nonrandomized study conducted during control (July-August 2007), an intervention (September 2007-April 2008), follow-up...
Large multicenter studies validating the prognostic value of coronary computed tomographic angiography (CCTA) and left ventricular ejection fraction (LVEF) are lacking. We sought to confirm independent incremental artery disease (CAD) severity measured using 64-slice CCTA over LVEF clinical variables.A large international registry (CONFIRM Registry) was queried, patients with data on were screened. Patients a history myocardial infarction, revascularization, or cardiac transplantation...
Objective— We sought to examine the risk of mortality associated with nonobstructive coronary artery disease (CAD) and determine impact baseline statin aspirin use on mortality. Approach Results— Coronary computed tomographic angiography permits direct visualization CAD. To date, prognostic implications CAD potential benefit directing therapy based have not been carefully examined. A total 27 125 consecutive patients who underwent (12 enrolling centers 6 countries) were prospectively entered...
We examined the prevalence, extent, severity, and prognosis of coronary artery disease (CAD) in individuals with without diabetes (DM) who are similar CAD risk factors.We identified 23,643 consecutive known undergoing computed tomography angiography. A total 3,370 DM were propensity matched a 1-to-2 fashion to 6,740 unique non-DM individuals. was defined as none, nonobstructive (1-49% stenosis), or obstructive (≥ 50% stenosis). All-cause mortality assessed by risk-adjusted Cox proportional...