A5087443191- Cardiac Arrest and Resuscitation
- Traumatic Brain Injury and Neurovascular Disturbances
- Traumatic Brain Injury Research
- Posttraumatic Stress Disorder Research
- Trauma and Emergency Care Studies
- Cardiac Imaging and Diagnostics
- Acute Myocardial Infarction Research
- Emergency and Acute Care Studies
- Resilience and Mental Health
- Migration, Health and Trauma
- Radiation Dose and Imaging
- Ultrasound in Clinical Applications
- Anesthesia and Neurotoxicity Research
- Thermal Regulation in Medicine
- Child Abuse and Trauma
- Venous Thromboembolism Diagnosis and Management
- Heart Failure Treatment and Management
- Cardiac, Anesthesia and Surgical Outcomes
- Stress Responses and Cortisol
- Advanced X-ray and CT Imaging
- Functional Brain Connectivity Studies
- Pneumonia and Respiratory Infections
- Disaster Response and Management
- Neonatal and fetal brain pathology
- Intensive Care Unit Cognitive Disorders
Wayne State University
2016-2025
Detroit Receiving Hospital
1997-2025
University of Ulster
2024
Emory University
2009-2023
University of Michigan–Ann Arbor
2023
Institute for Behavioral Medicine
2023
The University of Texas Health Science Center at Houston
2023
McLean Hospital
2021-2022
Temple University
2022
Provision Healthcare
2022
Mild traumatic brain injury (mTBI) accounts for more than 1 million emergency visits each year. Most of the injured stay in department a few hours and are discharged home without specific follow-up plan because their negative clinical structural imaging. Advanced magnetic resonance imaging (MRI), particularly functional MRI (fMRI), has been reported as being sensitive to disturbances after injury. In this study, cohort 12 patients with mTBI were prospectively recruited from our local Level-1...
Mild traumatic brain injury (mTBI) is a significant public health care burden in the United States. However, we lack detailed understanding of pathophysiology following mTBI and its relation to symptoms recovery. With advanced magnetic resonance imaging (MRI), can investigate perfusion oxygenation regions known be implicated symptoms, including cortical gray matter subcortical structures. In this study, assessed 14 patients 18 controls with susceptibility weighted mapping (SWIM) for blood...
Seasonal influenza causes >200 000 annual hospitalizations in the United States. Current antiviral treatment options are limited to oral or inhaled agents. There is an urgent unmet need for intravenous treatments.Patients hospitalized with suspected were randomized 5-day peramivir (600 mg once daily) placebo; all received institution's standard of care (SOC) treatment. Time clinical resolution and change viral shedding nasopharyngeal specimens primary key secondary end points.Influenza...
Major negative life events, such as trauma exposure, can play a key role in igniting or exacerbating psychopathology. However, few disorders are diagnosed with respect to precipitating and the of these events unfolding new psychopathology is not well understood. The authors conducted multisite transdiagnostic longitudinal study exposure related mental health outcomes identify neurobiological predictors risk, resilience, different symptom presentations.
Objective: Dissociation, a disruption or discontinuity in psychological functioning, is often linked with worse psychiatric symptoms; however, the prognostic value of dissociation after trauma inconsistent. Determining whether trauma-related uniquely predictive later outcomes would enable early identification at-risk populations. The authors conducted largest prospective longitudinal biomarker study persistent to date determine its capacity for adverse following acute trauma. Methods: All...
To prospectively evaluate the enhancement of coronary, pulmonary, and thoracic aortic vasculature by using biphasic single-acquisition 64-section computed tomographic (CT) angiography to if differences in right side heart coronary venous interfere with interpretation arteries.With internal review board approval HIPAA compliance, 50 patients (16 men, 34 women; mean age, 51.5 years; range, 30-75 years) atypical chest pain were referred from emergency department imaged a CT scanner after...
BackgroundMild traumatic brain injury (mTBI) is a significant healthcare burden and its diagnosis remains challenge in the emergency department. Serum biomarkers advanced magnetic resonance imaging (MRI) techniques have already demonstrated their potential to improve detection of even patients with negative computed tomography (CT) findings. The objective this study was determine clinical value combinational use both blood MRI mTBI characterization acute setting (within 24 hours after...
Abstract Patients exposed to trauma often experience high rates of adverse post-traumatic neuropsychiatric sequelae (APNS). The biological mechanisms promoting APNS are currently unknown, but the microbiota-gut-brain axis offers an avenue understanding as well possibilities for intervention. Microbiome composition after exposure has been poorly examined regarding outcomes. We aimed determine whether gut microbiomes trauma-exposed emergency department patients who develop have dysfunctional...
Seasonal interpandemic influenza causes >200,000 annual hospitalizations in the United States. Optimal antiviral treatment hospitalized patients is not established.During three seasons, 137 with suspected acute were randomized to 5-day intravenous peramivir 400 mg or 200 once daily oral oseltamivir 75 twice daily. Time clinical stability and quantitative changes viral titres from nasopharyngeal specimens primary key secondary end points, respectively.Infection was confirmed 122 A (H1N1),...