Thomas C. Neylan

ORCID: 0000-0002-1572-2626
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About
Contact & Profiles
Research Areas
  • Posttraumatic Stress Disorder Research
  • Sleep and related disorders
  • Sleep and Wakefulness Research
  • Stress Responses and Cortisol
  • Traumatic Brain Injury Research
  • Resilience and Mental Health
  • Anesthesia and Neurotoxicity Research
  • Migration, Health and Trauma
  • Tryptophan and brain disorders
  • Child Abuse and Trauma
  • Circadian rhythm and melatonin
  • Sleep and Work-Related Fatigue
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Parkinson's Disease Mechanisms and Treatments
  • Dementia and Cognitive Impairment Research
  • Healthcare professionals’ stress and burnout
  • Alzheimer's disease research and treatments
  • Functional Brain Connectivity Studies
  • Suicide and Self-Harm Studies
  • Intensive Care Unit Cognitive Disorders
  • Cardiac Arrest and Resuscitation
  • Psychosomatic Disorders and Their Treatments
  • Treatment of Major Depression
  • COVID-19 and Mental Health
  • Memory and Neural Mechanisms

San Francisco VA Medical Center
2016-2025

University of California, San Francisco
2016-2025

San Francisco VA Health Care System
2017-2025

Northern California Institute for Research and Education
2012-2025

Pacific Clinical Research
2020-2025

University Memory and Aging Center
2017-2024

University of North Carolina at Chapel Hill
2023

Alzheimer’s Disease Neuroimaging Initiative
2023

Park Terrace Care Center
2023

VA Puget Sound Health Care System
2023

OBJECTIVE: Meeting criterion A2 for the diagnosis of posttraumatic stress disorder (PTSD) in DSM-IV requires that an individual have high levels distress during or after traumatic event. Because paucity valid and reliable instruments assessing such responses, authors developed a 13-item self-report measure, Peritraumatic Distress Inventory, to obtain quantitative measure level experienced immediately METHOD: The cross-sectional study group comprised 702 police officers 301 matched nonpolice...

10.1176/appi.ajp.158.9.1480 article EN American Journal of Psychiatry 2001-09-01

<h3>Context</h3> Posttraumatic stress disorder (PTSD) is highly prevalent among US veterans because of combat and may impair cognition. <h3>Objective</h3> To determine whether PTSD associated with the risk developing dementia older receiving treatment in Department Veterans Affairs medical centers. <h3>Design</h3> A stratified, retrospective cohort study conducted using National Patient Care Database. <h3>Setting</h3> centers United States. <h3>Participants</h3> total 181 093 55 years or...

10.1001/archgenpsychiatry.2010.61 article EN Archives of General Psychiatry 2010-06-01

Record numbers of Iraq and Afghanistan veterans survive their war injuries yet continue to experience pain mental health problems, particularly posttraumatic stress disorder (PTSD). Little is known about the association disorders prescription opioid use.To investigate effect disorders, PTSD, on risks adverse clinical outcomes associated with use.Retrospective cohort study involving 141,029 who received at least 1 non-cancer-related diagnosis within year entering Department Veterans Affairs...

10.1001/jama.2012.234 article EN JAMA 2012-03-06

OBJECTIVE: This study analyzed questionnaire items that address complaints about sleep from the National Vietnam Veterans Readjustment Study, a nationally representative sample of 3.1 million men and women who served in Vietnam. compared frequency nightmares difficulties with onset maintenance male theater veterans era veteran civilian comparison subjects. It focused on role combat exposure, nonsleep posttraumatic stress disorder (PTSD) symptoms, comorbid psychiatric medical disorder,...

10.1176/ajp.155.7.929 article EN American Journal of Psychiatry 1998-07-01

Context: Most neuroimaging studies of posttraumatic stress disorder (PTSD) have focused on potential abnormalities in the whole hippocampus, but subfields this structure, which distinctive histological characteristics and specialized functions, not been investigated.Studies individual may clarify role hippocampus PTSD.Objective: To determine if PTSD is associated with structural alterations specific hippocampus.Design: Case-control study.Participants: A total 17 male veterans combat trauma...

10.1001/archgenpsychiatry.2009.205 article EN Archives of General Psychiatry 2010-03-01

Examine whether cognitive behavioral therapy for insomnia (CBT-I) improves sleep in posttraumatic stress disorder (PTSD) as well nightmares, nonsleep PTSD symptoms, depression and psychosocial functioning. RANDOMIZED CONTROLLED TRIAL WITH TWO ARMS: CBT-I monitor-only waitlist control. Department of Veterans Affairs (VA) Medical Center. Forty-five adults (31 females: [mean age 37 y (22-59 y)] with meeting research diagnostic criteria insomnia, randomly assigned to (n = 29; 22 females) or...

10.5665/sleep.3408 article EN SLEEP 2014-01-31

To determine if a treatment for interepisode bipolar disorder I patients with insomnia improves mood state, sleep, and functioning.Alongside psychiatric care, participants were randomly allocated to disorder-specific modification of cognitive behavior therapy (CBTI-BP; n = 30) or psychoeducation (PE; 28) as comparison condition. Outcomes assessed at baseline, the end 8 sessions treatment, 6 months later. This pilot was conducted initial feasibility generate effect size estimates.During...

10.1037/a0038655 article EN other-oa Journal of Consulting and Clinical Psychology 2015-01-26

Objectives To investigate the objective sleep influencers behind older adult responses to subjective measures, in this case, Pittsburgh Sleep Quality Index (PSQI). Based on previous literature, we hypothesized that SE would be associated with PSQI reported disruption. Furthermore, because SOL increases progressively age and it tends easily remembered by patients, also expected one of main predictors perceived quality elderly. Methods We studied 32 cognitively healthy community-dwelling...

10.1371/journal.pone.0270095 article EN cc-by PLoS ONE 2022-06-24

This study examined the relationship between routine work environment stress and posttraumatic disorder (PTSD) symptoms in a sample of police officers (N = 180) who were first assessed during academy training reassessed 1-year later. In model that included gender, ethnicity, traumatic exposure prior to entering academy, current negative life events, critical incident over last year, was most strongly associated with PTSD symptoms. We also found mediated events Ensuring is functioning...

10.1097/nmd.0b013e3181b975f8 article EN The Journal of Nervous and Mental Disease 2009-10-01

Background The United States military has lost more troops to suicide than combat for the second year in a row and better understanding combat-related risk factors is critical. We examined association of killing among war veterans after accounting PTSD, depression, substance use disorders. Methods utilized cross-sectional, retrospective, nationally representative sample Vietnam from National Veterans Readjustment Study (NVVRS). In order perform depth analysis, we subsample these data, NVVRS...

10.1002/da.21954 article EN Depression and Anxiety 2012-04-13

Short sleep duration is associated with an increased risk of type 2 diabetes. Subchronic restriction (SR) causes insulin resistance, but the mechanisms and roles specific tissues are unclear.The purpose this article was to determine whether subchronic SR altered (1) hepatic sensitivity, (2) peripheral (3) substrate utilization.This a randomized crossover study in which 14 subjects underwent admissions separated by washout period. Each admission had acclimatization nights followed 5 either (4...

10.1210/jc.2014-3911 article EN The Journal of Clinical Endocrinology & Metabolism 2015-02-06
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