A5077381580- Functional Brain Connectivity Studies
- Traumatic Brain Injury Research
- Traumatic Brain Injury and Neurovascular Disturbances
- Advanced Neuroimaging Techniques and Applications
- Intracerebral and Subarachnoid Hemorrhage Research
- Advanced MRI Techniques and Applications
- Neonatal Respiratory Health Research
- Congenital Diaphragmatic Hernia Studies
- Atomic and Subatomic Physics Research
- MRI in cancer diagnosis
- Liver Disease Diagnosis and Treatment
- Respiratory Support and Mechanisms
- Cardiac Arrest and Resuscitation
- Neural dynamics and brain function
Wayne State University
2015-2023
Mild traumatic brain injury (mTBI) is a significant public health care burden in the United States. However, we lack detailed understanding of pathophysiology following mTBI and its relation to symptoms recovery. With advanced magnetic resonance imaging (MRI), can investigate perfusion oxygenation regions known be implicated symptoms, including cortical gray matter subcortical structures. In this study, assessed 14 patients 18 controls with susceptibility weighted mapping (SWIM) for blood...
Spontaneous fluctuations of resting state functional MRI (rsfMRI) have been widely used to understand the macro-connectome human brain. However, these are not synchronized among subjects, which leads limitations and makes utilization first-level model-based methods challenging. Considering this limitation rsfMRI data in time domain, we propose transfer spatiotemporal information another connectivity each value represents same effect across subjects. Using a set seed networks index calculate...
Mild traumatic brain injury (mTBI) is a major public health concern. Functional MRI has reported alterations in several networks following mTBI. However, the connectome-scale network changes are still unknown. In this study, sixteen mTBI patients were prospectively recruited from an emergency department and followed up at 4–6 weeks after injury. Twenty-four healthy controls also scanned twice with same time interval. Three hundred fifty-eight landmarks that preserve structural functional...
Mild traumatic brain injury (mTBI) accounts for over one million emergency visits each year in the United States. The large-scale structural and functional network connectivity changes of mTBI are still unknown. This study was designed to determine connectome-scale at both levels. 40 patients acute stage 50 healthy controls were recruited. A novel approach called Dense Individualized Common Connectivity-based Cortical Landmarks (DICCCOLs) applied analysis diffusion tensor imaging resting...
Micro-hemorrhages are a common result of traumatic brain injury (TBI), which can be quantified with susceptibility weighted imaging and mapping (SWIM), quantitative approach. A total 23 TBI patients (five women, 18 men; median age, 41.25 years old; range, 21.69–67.75 years) an average Glasgow Coma Scale score 7 (range, 3–15) at admission were recruited mean 149 d 57–366) after injury. Susceptibility-weighted data collected post-processed to create SWIM images. The value small hemorrhages...
Abstract Cirrhosis is a major public health concern. However, little known about the neurobiological mechanisms underlying brain microstructure alterations in cirrhotic patients. The purpose of this prospective study was to investigate microstructural cirrhosis with or without minimal hepatic encephalopathy (MHE) and their relationship patients’ neurocognitive performance disease duration using voxel-based analysis diffusion kurtosis imaging (DKI). DKI data were acquired from 30 patients...
Functional connectivity in the brain is often studied with blood-level oxygen dependent (BOLD) resting state functional magnetic resonance imaging (rsfMRI), but BOLD signal several steps removed from neuronal activity. Arterial spin labeling (ASL), particularly pulsed ASL (PASL), has also capacity to measure blood-flow changes response In this paper, we investigated feasibility of extracting major networks PASL data, contrast rsfMRI analsyis. retrospective study, analyzed a cohort dataset...
A clinical decision report appraising: Kaminski PN, Forgiarini LA, Jr., Andrade CF. Early respiratory therapy reduces postoperative atelectasis in children undergoing lung resection. Respir Care. 2013;58(5):805-809. https://doi.org/10.4187/respcare.01870 for prevention of pulmonary complications following thoracic surgery a patient who is not able to participate incentive spirometry.