A5021467518- Cardiac Imaging and Diagnostics
- Coronary Interventions and Diagnostics
- Acute Myocardial Infarction Research
- Advanced X-ray and CT Imaging
- Cerebrovascular and Carotid Artery Diseases
- Cardiovascular Disease and Adiposity
- Cardiovascular Function and Risk Factors
- Lipoproteins and Cardiovascular Health
- Radiation Dose and Imaging
- Advanced MRI Techniques and Applications
- Acute Ischemic Stroke Management
- Ocular Diseases and Behçet’s Syndrome
- Cancer, Lipids, and Metabolism
- Liver Disease Diagnosis and Treatment
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Metabolomics and Mass Spectrometry Studies
- Chemotherapy-induced cardiotoxicity and mitigation
- Cardiovascular Health and Risk Factors
- Diet, Metabolism, and Disease
- Health and Medical Research Impacts
- Vitamin K Research Studies
- Counseling Practices and Supervision
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Cancer Risks and Factors
- Apelin-related biomedical research
Weill Cornell Medicine
2017-2024
Cornell University
2009-2024
University of Northern Colorado
2023
Penn Presbyterian Medical Center
2018-2022
The University of Texas Health Science Center at Houston
2022
Presbyterian Hospital
2016-2021
New York Hospital Queens
2016-2021
NewYork–Presbyterian Hospital
2016-2021
CVPath Institute
2018
Gangnam Severance Hospital
2018
Symptom-based pretest probability scores that estimate the likelihood of obstructive coronary artery disease (CAD) in stable chest pain have moderate accuracy. We sought to develop a machine learning (ML) model, utilizing clinical factors and calcium score (CACS), predict presence CAD on computed tomography angiography (CCTA).
<h3>Importance</h3> Plaque morphologic measures on coronary computed tomography angiography (CCTA) have been associated with future acute syndrome (ACS). However, the evolution of calcified plaques by noninvasive imaging is not known. <h3>Objective</h3> To ascertain whether increasing density in plaque risk for ACS. <h3>Design, Setting, and Participants</h3> This multicenter case-control cohort study included individuals enrolled ICONIC (Incident Coronary Syndromes Identified Computed...
Objectives We prospectively examined whether socioeconomic status (SES) predicts incident type II diabetes (diabetes), a cardiovascular risk equivalent and burgeoning public health epidemic among women. Methods Participants include 23,992 women with HbA1c levels <6% no CVD or at baseline followed from February 1993 to March 2007. SES was measured by education income while self-reported. Results Over 12.3 years of follow-up, 1,262 developed diabetes. In age race adjusted models, the relative...
Background This study aimed to explore whether statins reduce radiation‐induced vascular complications in cancer patients postradiotherapy the thorax, head, and neck. Methods Results We conducted a retrospective cohort within provincial linked database of 5718 cardiac with thorax head or neck having undergone radiotherapy between 2000 2011. One thousand five hundred fifty‐two were identified as nonstatin users 4166 statin users. The primary outcome interest was composite cerebrovascular...
Abstract Aims In patients without obstructive coronary artery disease (CAD), we examined the prognostic value of risk factors and atherosclerotic extent. Methods results Patients from long-term CONFIRM registry prior CAD (≥50%) stenosis were included. Within groups normal computed tomography angiography (CCTA) (N = 1849) non-obstructive 1698), traditional clinical extent (segment involvement score, SIS) was assessed with Cox models. Major adverse cardiac events (MACE) defined as all-cause...
Osteoporosis and cardiovascular disease may share common biological pathways, with inflammation playing a role in the development of both. Although observational studies have suggested that statin use is associated lower risk fractures, randomized trial data addressing this issue are scant.
Many academic institutions strive to promote more diverse and inclusive campuses for faculty, staff, students. As part of this effort, these seek include individuals from historically underrepresented groups (URGs)-such as women, people racial/ethnic minority populations, persons with disabilities-on committees in other service activities. However, given the low number faculty members URGs at many institutions, tend receive requests provide institution or department (e.g., serving on...
<h3>OBJECTIVES</h3> Several lines of evidence suggest that the endothelial constitutive nitric oxide synthase (ecNOS) and angiotensin converting enzyme (ACE) may have a role in Alzheimer9s disease. ACE is widely expressed brain, DNA polymorphism at gene has been linked to risk for late onset Nitric (NO) production by microglial cells, astrocytes, brain microvessels enhanced patients with There growing NO involved neuronal death disease, oxidative stress caused could be pathogenic mechanism...
Background Low-density lipoprotein cholesterol (LDL-C) is a target for cardiovascular prevention. Contemporary equations LDL-C estimation have limited accuracy in certain scenarios (high triglycerides [TG], very low LDL-C). Objectives We derived novel method from the standard lipid profile using machine learning (ML) approach utilizing random forests (the Weill Cornell model). compared its correlation to direct with Friedewald and Martin-Hopkins estimation. Methods The study cohort comprised...
Abstract Aims There are significant sex-specific differences in left ventricular ejection fraction (LVEF), with a higher LVEF being observed women. We sought to assess the clinical relevance of an increased women and men. Methods results A total 4632 patients from CONFIRM (COronary CT Angiography EvaluatioN For Clinical Outcomes: An InteRnational Multicenter) registry (44.8% women; mean age 58.7 ± 13.2 years men 59.5 13.3 women, P = 0.05), whom was measured by cardiac computed tomography,...
BackgroundAtherosclerotic cardiovascular disease (ASCVD) remains the leading cause of death in United States. Case-based learning using electronic delivery modules can educate clinicians and improve translation evidence-based guidelines into practice for high-risk ASCVD patients.ObjectiveTo develop optimize module design, content, usability e-learning to teach management accordance with multi-society patients that will be implemented evaluated U.S. health systems TEACH-ASCVD...
Background The extent to which the presence and of subclinical atherosclerosis by coronary computed tomography angiography influences a potential mortality benefit statin is unknown. We evaluated relationship between therapy, mortality, atherosclerosis. Methods In CONFIRM study, patients with normal or non-obstructive plaque (<50% diameter stenosis) for whom data on baseline use was available were included. Coronary artery calcium (CAC) quantified using Agatston score. segment involvement...