- Cardiac Imaging and Diagnostics
- Cardiac Valve Diseases and Treatments
- Infective Endocarditis Diagnosis and Management
- Coronary Interventions and Diagnostics
- Cardiovascular Function and Risk Factors
- Acute Myocardial Infarction Research
- Antimicrobial Resistance in Staphylococcus
- Advanced X-ray and CT Imaging
- Heart Failure Treatment and Management
- Aortic Disease and Treatment Approaches
- Cerebrovascular and Carotid Artery Diseases
- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Streptococcal Infections and Treatments
- Cardiac electrophysiology and arrhythmias
- Bacterial Identification and Susceptibility Testing
- Radiation Dose and Imaging
- Cardiac Structural Anomalies and Repair
- Cardiac pacing and defibrillation studies
- Cardiovascular and Diving-Related Complications
- Cardiovascular Disease and Adiposity
- Advanced MRI Techniques and Applications
- Venous Thromboembolism Diagnosis and Management
- Cardiac tumors and thrombi
- Diverse Scientific Research Studies
University of Lausanne
2019-2025
University Hospital of Lausanne
2019-2025
University of British Columbia
2021-2024
St. Paul's Hospital
2021-2024
Cardiovascular Research Foundation
2024
Fiona Stanley Hospital
2024
Harry Perkins Institute of Medical Research
2024
Curtin University
2024
University of Liverpool
2023
Aarhus University Hospital
2023
Abstract Background Since publication of Duke criteria for infective endocarditis (IE) diagnosis, several modifications have been proposed. We aimed to evaluate the diagnostic performance Duke-ISCVID (International Society Cardiovascular Infectious Diseases) 2023 compared prior versions from 2000 (Duke-Li 2000) and 2015 (Duke-ESC [European Cardiology] 2015). Methods This study was conducted at 2 university hospitals between 2014 2022 among patients with suspected IE. A case classified as IE...
With growing adoption of coronary computed tomographic angiography (CTA), there is increasing evidence for and interest in the prognostic importance atherosclerotic plaque volume. Manual tools segmentation are cumbersome, their routine implementation clinical practice limited. The aim this study was to develop nomographic quantitative values from a large consecutive multicenter cohort using CTA. Quantitative assessment total subtype volumes performed patients undergoing clinically indicated...
Abstract Background The Duke criteria for infective endocarditis (IE) diagnosis underwent revisions in 2023 by the European Society of Cardiology (ESC) and International Cardiovascular Infectious Diseases (ISCVID). This study aims to assess diagnostic accuracy these criteria, focusing on patients with Staphylococcus aureus bacteremia (SAB). Methods Swiss multicenter conducted between 2014 pooled data from three cohorts. It evaluated performance each iteration assessing degree concordance...
BACKGROUND: Luminal stenosis, computed tomography–derived fractional-flow reserve (FFR CT ), and high-risk plaque features on coronary tomography angiography are all known to be associated with adverse clinical outcomes. The interactions between these variables, patient outcomes, quantitative volumes have not been previously described. METHODS: Patients (n=4430) one-year outcome data from the international ADVANCE (Assessing Diagnostic Value of Noninvasive FFR in Coronary Care) registry...
Abstract Background Streptococci are a common cause of infective endocarditis (IE). We aimed to evaluate the performance HANDOC score identify patients at high risk for IE and Duke clinical criteria European Society Cardiology (ESC; 2015 2023 versions) version from International Cardiovascular Infectious Diseases (ISCVID) in diagnosing among with streptococcal bacteremia. Methods This retrospective study included adult bacteremia hospitalized Lausanne University Hospital. Episodes were...
Automated artificial intelligence–based quantification of coronary plaque volume from cardiac CT was highly correlated with the invasive reference standard intravascular ultrasound.
BACKGROUND: Transcatheter heart valve (THV) underexpansion after transcatheter aortic replacement may be associated with worse outcomes. THV expansion can assessed fluoroscopically using a pigtail for calibration; however, the accuracy of this technique specific to is unknown. We and reproducibility novel fluoroscopic method assess commissural post calibration. METHODS: Patients who underwent SAPIEN 3 (S3) had documented cusp overlap views, post-implant computed tomography was identified. in...
Abstract Background Percutaneous left atrial appendage occlusion (LAAO) is typically performed under the guidance of transesophageal echocardiography (TEE) and fluoroscopy. Intracardiac (ICE) appears to be a potential alternative guide implantation. Purpose We sought perform meta-analysis comparing ICE vs TEE for percutaneous LAAO. Methods A comprehensive literature search was using MEDLINE, Scopus Web Science electronic databases from their inception November 2023 regarding published...
Abstract Background Echocardiographic grading of mitral regurgitation (MR) relies on the interpretation both quantitative and qualitative parameters. Contemporary societal guidelines suggest a diagnostic approach that primarily favors parameters.1 We aimed to assess accuracy such an in comparison by cardiac magnetic resonance (CMR). Methods Patients with primary were assessed transthoracic transesophageal echocardiography (TTE, TOE), as well resonance. Mitral was considered severe if...
Abstract Background Mitral valve prolapse (MVP) is heterogenous, ranging from localized disease to diffuse bi-leaflet involvement in Barlow myxoid degeneration. regurgitation (MR) may be or diffuse, holosystolic end-systolic, depending on the morphology. We aimed compare diagnostic accuracy of effective regurgitant orifice by conventional 2D PISA (ERO) transthoracic echocardiography (TTE) with 3D vena contracta area (3D-VCA) transoesophageal (TOE) patients and MVP. Methods Patients MVP...
Abstract Cardiac computed tomography (CCT) continues to expand with increasing applications and technological advancements. Growing evidence on the clinical utility of CCT necessitates evaluating how this knowledge is incorporated into European Society Cardiology (ESC) American College (ACC)/American Heart Association (AHA) guidelines. We aimed provide a comprehensive comparison indications between ESC ACC/AHA guidelines identify areas consensus divergence in current landscape utilization....
Transcatheter aortic valve replacement (TAVR) has revolutionized the treatment of stenosis. As TAVR continues to evolve, precise pre-procedural planning and imaging have become increasingly critical. While transthoracic echocardiography remains indispensable for assessing severity stenosis, cardiac computed tomography angiography (CCTA) emerged as benchmark modality TAVR. CCTA provides detailed anatomical information essential patient selection, procedural success, mitigation complications....
Abstract Purpose To ascertain the predictors of persistent bacteraemia among patients with suspected infective endocarditis (IE) and those IE. Methods Retrospective study. Setting This study conducted at a Swiss university hospital (2015–2023) included adult Persistent was defined as continued positive blood cultures same microorganism for least 48 h from antibiotic treatment initiation. Endocarditis Team classified cases IE or not Results Among 2312 episodes IE, S. aureus most common...