A5077774990- Cardiac Imaging and Diagnostics
- Advanced X-ray and CT Imaging
- Cardiovascular Function and Risk Factors
- Coronary Interventions and Diagnostics
- Aortic aneurysm repair treatments
- Radiation Dose and Imaging
- Lipoproteins and Cardiovascular Health
- Aortic Disease and Treatment Approaches
- Acute Myocardial Infarction Research
- Blood Pressure and Hypertension Studies
- Cardiac, Anesthesia and Surgical Outcomes
- Ultrasound in Clinical Applications
- Atrial Fibrillation Management and Outcomes
- Vitamin K Research Studies
- Cardiovascular Disease and Adiposity
- Cardiovascular Health and Disease Prevention
- Cardiac Valve Diseases and Treatments
- Hemodynamic Monitoring and Therapy
- Renal and Vascular Pathologies
- Congenital Heart Disease Studies
- Pericarditis and Cardiac Tamponade
- Radiology practices and education
- Health Promotion and Cardiovascular Prevention
- Asthma and respiratory diseases
- Parathyroid Disorders and Treatments
Svendborg Sygehus
2016-2025
Odense University Hospital
2016-2025
University of Southern Denmark
2013-2025
Vejle Sygehus
2020-2022
Bispebjerg Hospital
2022
Regional Health
2011
Respiratory Clinical Trials
2000
Advances of cardiac computed tomography angiography (CTA) have been developed for dose reduction, but their efficacy in clinical practice is largely unknown. This study was designed to evaluate radiation exposure and utilization dose-saving strategies contrast-enhanced CTA daily practice. Sixty one hospitals from 32 countries prospectively enrolled 4502 patients undergoing during calendar month 2017. Computed scan data images were analysed a central core lab compared with similar survey...
Limited data suggest a benefit of population-based screening for cardiovascular disease with respect to the risk death.We performed population-based, parallel-group, randomized, controlled trial involving men 65 74 years age living in 15 Danish municipalities. The participants were randomly assigned 1:2 ratio undergo (the invited group) or not control subclinical disease. Randomization was based on computer-generated random numbers and stratified according municipality. Only group unaware...
Menaquinone-7 (MK-7), also known as vitamin K2, is a cofactor for the carboxylation of proteins involved in inhibition arterial calcification and has been suggested to reduce progression rate aortic valve (AVC) patients with stenosis.In randomized, double-blind, multicenter trial, men from community an AVC score >300 arbitrary units (AU) on cardiac noncontrast computer tomography were randomized daily treatment tablet 720 µg MK-7 plus 25 D or matching placebo 24 months. The primary outcome...
Intense physical activity in children may either improve fitness and protect against asthma, or trigger symptoms. The aim of this study was to determine whether childhood has an impact on the development asthma. In prospective, community-based study, 757 (84%) asymptomatic with average age at inclusion 9.7 yrs were followed for 10.5 yrs. both surveys a maximal progressive exercise test bicycle ergometer used measure (maximal workload) induce airway narrowing. A methacholine provocation...
Systemic inflammation has been associated with reduced lung function. However, data on the interrelationships between function and are sparse, it is not clear if low-grade leads to Associations high-sensitive C-reactive protein (CRP) spirometric were assessed in a population-based cohort of ∼1,000 Danes aged 20 yrs. In males, average decline forced expiratory volume one second (FEV 1 ) highest CRP quintile was 23 mL·yr −1 versus 1.6 lowest quintile. females, 6.2 an increase 1.8 multiple...
To examine the 3.5 year prognosis of stable coronary artery disease (CAD) as assessed by computed tomography angiography (CCTA) in real-world clinical practice, overall and within subgroups patients according to age, sex, comorbidity.This cohort study included 16,949 (median age 57 years; 57% women) with new-onset symptoms suggestive CAD, who underwent CCTA between January 2008 December 2012. The endpoint was a composite late revascularization procedure >90 days after CCTA, myocardial...
The significant increase in the average life expectancy has increased societal challenge of managing serious age-related diseases, especially cancer and cardiovascular diseases. A routine check by a general practitioner is not sufficient to detect incipient disease. Population-based randomized clinically controlled screening trial. Participants: 45,000 Danish men aged 65–74 years living on Island Funen, or surrounding communities Vejle Silkeborg. No exclusion criteria are used....
Background: Coronary artery calcification (CAC) is an independent and incremental risk marker. This marker has previously not been compared to the HeartScore model. Design: A random sample of 1825 citizens (men women, 50 or 60 years age) was invited for screening. Methods: Using model, 10-year fatal cardiovascular events based on gender, age, smoking, systolic blood pressure, total cholesterol estimated. low defined as <5%. The CAC score calculated from a non-contrast enhanced cardiac-CT...
Abstract Background The challenge of managing age-related diseases is increasing; routine checks by the general practitioner do not reduce cardiovascular mortality. aim here was to mortality advanced population-based screening. present article reports organization study, acceptability screening offer, and relevance multifaceted for prevention management disease. Methods Danish men aged 65–74 years were invited randomly (1 : 2) a examination using low-dose non-contrast CT, ankle brachial BP...
Impaired glucose tolerance (IGT), a prediabetic state, is known risk factor for coronary artery disease (CAD). Low-attenuation plaque (LAP) lesions are associated with high of events. We aimed to evaluate high-risk characteristics in LAP between patients IGT and normal (NGT) suspected stable CAD. Coronary computed tomography angiography (CCTA) identified assessed volumes, burdens, features. Glycemic was stratified using oral tests. Among 148 patients, 202 were identified, 93 classified as...
Investigate sex-specific associations between total cholesterol, non-high-density lipoprotein cholesterol (non-HDL-C) and the burden of atherosclerosis assessed by coronary artery calcium (CAC) score. A 10,049 participants (women: 958, men: 9,091) aged 49-75 years, without known cardiovascular disease (CVD) or current use lipid-lowering medication, were included from Danish Risk Score study Cardiovascular Screening Trial cohorts. Logistic regression models zero-inflated negative binomial...
This study aims to describe the prevalence of discordant mild/moderate aortic stenosis (AS) in a population-based and identify mechanisms that lead reduced stroke volume (SV) moderate AS. Discordant high-gradient (HG)-mild AS, defined as AVA > 1.5 cm2 mean pressure gradient (MG) 20-40 mmHg, low-gradient (LG) 1.0-1.5 MG < 20 were assessed 883 individuals from DANCAVAS screening with valve calcification 257 form PROGRESSA excluding those left ventricular (LV) ejection fraction 50%. In cohort,...
Abstract Background Pericoronary adipose tissue attenuation (PCATa), derived from coronary computed tomography angiography (CCTA), is a novel marker of inflammation in the arteries. Patients with type 2 diabetes mellitus (T2DM) are at elevated risk artery disease (CAD), potentially due to systemic inflammation. This study evaluated whether baseline PCATa predicts changes plaque composition and burden over 12 months. Methods prospective longitudinal included 200 participants T2DM, who had...