Philippe Pîbarot
A5009728510- Cardiac Valve Diseases and Treatments
- Infective Endocarditis Diagnosis and Management
- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- Aortic Disease and Treatment Approaches
- Cardiac Structural Anomalies and Repair
- Cardiac pacing and defibrillation studies
- Coronary Interventions and Diagnostics
- Cardiac, Anesthesia and Surgical Outcomes
- Lipoproteins and Cardiovascular Health
- Atrial Fibrillation Management and Outcomes
- Congenital Heart Disease Studies
- Cardiac Arrhythmias and Treatments
- Cardiomyopathy and Myosin Studies
- Pulmonary Hypertension Research and Treatments
- Cardiovascular Disease and Adiposity
- Aortic Thrombus and Embolism
- Mechanical Circulatory Support Devices
- Heart Failure Treatment and Management
- Phonocardiography and Auscultation Techniques
- Cardiac and Coronary Surgery Techniques
- Advanced MRI Techniques and Applications
- Aortic aneurysm repair treatments
- Cardiovascular Effects of Exercise
- Amyloidosis: Diagnosis, Treatment, Outcomes
Institut Universitaire de Cardiologie et de Pneumologie de Québec
2016-2025
Université Laval
2016-2025
Montreal Heart Institute
2016-2025
Lung Institute
2015-2025
NewYork–Presbyterian Hospital
2013-2024
Leiden University Medical Center
2017-2024
Cardiovascular Research Foundation
2013-2024
Columbia University Irving Medical Center
2014-2024
GTx (United States)
2024
St. Francis Hospital
2024
Previous trials have shown that among high-risk patients with aortic stenosis, survival rates are similar transcatheter aortic-valve replacement (TAVR) and surgical replacement. We evaluated the two procedures in a randomized trial involving intermediate-risk patients.
Among patients with aortic stenosis who are at intermediate or high risk for death surgery, major outcomes similar transcatheter aortic-valve replacement (TAVR) and surgical replacement. There is insufficient evidence regarding the comparison of two procedures in low risk.
Guidelines •
AAA : abdominal aortic aneurysm ACEI : angiotensin converting enzyme inhibitor ACS : acute coronary syndromes AF : atrial fibrillation AKI : kidney injury AKIN : Acute Kidney Injury Network ARB : receptor blocker ASA : American Society of Anesthesiologists b.i.d. : bis in diem (twice daily) BBSA : Beta-Blocker Spinal Anesthesia BMS : bare-metal stent BNP : B-type natriuretic peptide bpm : beats per minute CABG : artery bypass graft CAD : disease CARP : Coronary Artery Revascularization...
Background— Recent studies and current clinical observations suggest that some patients with severe aortic stenosis on the basis of valve area may paradoxically have a relatively low gradient despite presence preserved left ventricular (LV) ejection fraction. The objective present study was to document prevalence, potential mechanisms, relevance this phenomenon. Methods Results— We retrospectively studied Doppler echocardiographic data 512 consecutive (indexed ≤0.6 cm 2 · m −2 ) LV fraction...
T he introduction of valve replacement surgery in the early 1960s has dramatically improved outcome patients with valvular heart disease.Approximately 90 000 substitutes are now implanted United States and 280 worldwide each year; approximately half mechanical valves bioprosthetic valves.Despite marked improvements prosthetic design surgical procedures over past decades, does not provide a definitive cure to patient.Instead, native disease is traded for "prosthetic disease," undergoing...
There are scant data on long-term clinical outcomes and bioprosthetic-valve function after transcatheter aortic-valve replacement (TAVR) as compared with surgical in patients severe aortic stenosis intermediate risk.We enrolled 2032 intermediate-risk severe, symptomatic at 57 centers. Patients were stratified according to intended transfemoral or transthoracic access (76.3% 23.7%, respectively) randomly assigned undergo either TAVR replacement. Clinical, echocardiographic, health-status...
Background— The prosthesis used for aortic valve replacement (AVR) can be too small in relation to body size, thus causing prosthesis-patient mismatch (PPM) and abnormally high transvalvular pressure gradients. This study examined if there is a between PPM short-term mortality after operation. Methods Results— indexed effective orifice area (EOA) was estimated each type size of being implanted 1266 consecutive patients define as not clinically significant >0.85 cm 2 /m , moderate >0.65...
The Valve Academic Research Consortium (VARC), founded in 2010, was intended to (i) identify appropriate clinical endpoints and (ii) standardize definitions of these for transcatheter surgical aortic valve trials. Rapid evolution the field, including emergence new complications, expanding indications, novel therapy strategies have mandated further refinement expansion ensure relevance. This document provides an update most endpoint be used conduct research.Several years after publication...
In patients with aortic stenosis (AS), risk stratification for valve replacement (AVR) relies mainly on valve-related factors, symptoms and co-morbidities. We sought to evaluate the prognostic impact of a newly-defined staging classification characterizing extent extravalvular (extra-aortic valve) cardiac damage among severe AS undergoing AVR.Patients from PARTNER 2 trials were pooled classified according presence or absence as detected by echocardiography prior AVR: no (Stage 0), left...
The ESC/EACTS Guidelines represent the views of ESC and EACTS were produced after careful consideration scientific medical knowledge evidence available at time their publication.The are not responsible in event any contradiction, discrepancy and/ or ambiguity between other official recommendations guidelines issued by relevant public health authorities, particular relation to good use healthcare therapeutic strategies.Health professionals encouraged take fully into account when exercising...
The impact of paravalvular regurgitation (PVR) following transcatheter aortic valve replacement (TAVR) remains uncertain. In this analysis, we sought to evaluate the varying degrees PVR on both mortality and changes in ventricular geometry function. Clinical echocardiographic outcomes patients who underwent TAVR from randomized cohorts continued access registries PARTNER trial were analysed after stratifying by severity post-implant PVR, which was graded as none/trace 52.9% (n = 1288), mild...