Björn Redfors
- Cardiac Imaging and Diagnostics
- Coronary Interventions and Diagnostics
- Acute Myocardial Infarction Research
- Cardiac Valve Diseases and Treatments
- Takotsubo Cardiomyopathy and Associated Phenomena
- Cardiovascular Function and Risk Factors
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac Structural Anomalies and Repair
- Atrial Fibrillation Management and Outcomes
- Cardiac pacing and defibrillation studies
- Infective Endocarditis Diagnosis and Management
- Health Systems, Economic Evaluations, Quality of Life
- Cardiac electrophysiology and arrhythmias
- Heart Failure Treatment and Management
- Cardiac Health and Mental Health
- Venous Thromboembolism Diagnosis and Management
- Cardiac and Coronary Surgery Techniques
- Mechanical Circulatory Support Devices
- Cardiac Arrest and Resuscitation
- Cardiovascular Issues in Pregnancy
- Aortic Disease and Treatment Approaches
- COVID-19 Clinical Research Studies
- Cardiac Ischemia and Reperfusion
- Statistical Methods in Clinical Trials
Sahlgrenska University Hospital
2016-2025
University of Gothenburg
2016-2025
Cardiovascular Research Foundation
2016-2025
Region Västra Götaland
2023-2025
Cornell University
2022-2025
Weill Cornell Medicine
2022-2025
National Academy of Medicine
2024-2025
New York Hospital Queens
2018-2024
Columbia University Irving Medical Center
2016-2024
NewYork–Presbyterian Hospital
2017-2024
In patients with aortic stenosis (AS), risk stratification for valve replacement (AVR) relies mainly on valve-related factors, symptoms and co-morbidities. We sought to evaluate the prognostic impact of a newly-defined staging classification characterizing extent extravalvular (extra-aortic valve) cardiac damage among severe AS undergoing AVR.Patients from PARTNER 2 trials were pooled classified according presence or absence as detected by echocardiography prior AVR: no (Stage 0), left...
Abstract The coronavirus disease 2019 (COVID-19) can result in a hyperinflammatory state, leading to acute respiratory distress syndrome (ARDS), myocardial injury, and thrombotic complications, among other sequelae. Statins, which are known have anti-inflammatory antithrombotic properties, been studied the setting of viral infections, but their benefit has not assessed COVID-19. This is retrospective analysis patients admitted with COVID-19 from February 1 st through May 12 th , 2020 study...
Importance Two initial sham-controlled trials demonstrated that ultrasound renal denervation decreases blood pressure (BP) in patients with mild to moderate hypertension and is resistant treatment. Objective To study the efficacy safety of without confounding influence antihypertensive medications hypertension. Design, Setting, Participants Sham-controlled, randomized clinical trial outcome assessors blinded treatment assignment was conducted between January 14, 2019, March 25, 2022, at 37...
Ultrasound renal denervation (uRDN) was shown to lower blood pressure (BP) in patients with uncontrolled hypertension (HTN). Establishing the magnitude and consistency of uRDN effect across HTN spectrum is clinically important.
BackgroundFor patients with asymptomatic severe aortic stenosis and preserved left ventricular ejection fraction, current guidelines recommend routine clinical surveillance every 6 to 12 months. Data from randomized trials examining whether early intervention transcatheter aortic-valve replacement (TAVR) will improve outcomes in these are lacking.MethodsAt 75 centers the United States Canada, we randomly assigned, a 1:1 ratio, undergo TAVR transfemoral placement of balloon-expandable valve...
Importance Trials showing equivalent or better outcomes with initial evaluation using coronary computed tomography angiography (cCTA) compared stress testing in patients stable chest pain have informed guidelines but raise questions about overtesting and excess catheterization. Objective To test a modified cCTA strategy designed to improve clinical efficiency vs usual (UT). Design, Setting, Participants This was pragmatic randomized trial enrolling participants from December 3, 2018, May 18,...
Abstract The win ratio was introduced in 2012 as a new method for examining composite endpoints and has since been widely adopted cardiovascular (CV) trials. Improving upon conventional methods analysing endpoints, the accounts relative priorities of components allows to be different types outcomes. For example, can combine time death with number occurrences non-fatal outcome such CV-related hospitalizations (CVHs) single hierarchical endpoint. provide greater statistical power detect...
Background Cardiovascular disease is the most common cause of death for both genders. Debates are ongoing as to whether gender‐specific differences in clinical course, diagnosis, and management acute myocardial infarction (MI) exist. Methods Results We compared all men women who were treated MI at cardiac care units Västra Götaland, Sweden, between January 1995 October 2014 by obtaining data from prospective SWEDEHEART (Swedish Web‐System Enhancement Evidence‐Based Care Heart Disease...