- Cardiac Valve Diseases and Treatments
- Cardiac Imaging and Diagnostics
- COVID-19 Clinical Research Studies
- Infective Endocarditis Diagnosis and Management
- Coronary Interventions and Diagnostics
- Cardiac Structural Anomalies and Repair
- Suicide and Self-Harm Studies
- Cardiovascular Function and Risk Factors
- Atherosclerosis and Cardiovascular Diseases
- Long-Term Effects of COVID-19
- Acute Myocardial Infarction Research
- SARS-CoV-2 and COVID-19 Research
- Cardiovascular Effects of Exercise
- Psychotherapy Techniques and Applications
- Cardiac, Anesthesia and Surgical Outcomes
- Transplantation: Methods and Outcomes
- Cardiac electrophysiology and arrhythmias
- Counseling Practices and Supervision
- Protease and Inhibitor Mechanisms
- Cardiac and Coronary Surgery Techniques
- Cardiac Arrhythmias and Treatments
- Cardiac pacing and defibrillation studies
- Gun Ownership and Violence Research
- Airway Management and Intubation Techniques
- COVID-19 and Mental Health
Columbia University Irving Medical Center
2010-2025
NewYork–Presbyterian Hospital
2010-2025
New York Hospital Queens
2010-2025
Columbia University
2000-2024
Cardiovascular Research Foundation
2024
Morristown Medical Center
2024
Cornell University
2024
St. Francis Hospital
2024
University of North Dakota
2023
National Institutes of Health
2023
Information about a real patient is presented in stages (boldface type) to expert clinicians (Drs Uriel and Sayer), who respond the information share their reasoning with reader (regular type
Abstract The coronavirus disease 2019 (COVID-19) can result in a hyperinflammatory state, leading to acute respiratory distress syndrome (ARDS), myocardial injury, and thrombotic complications, among other sequelae. Statins, which are known have anti-inflammatory antithrombotic properties, been studied the setting of viral infections, but their benefit has not assessed COVID-19. This is retrospective analysis patients admitted with COVID-19 from February 1 st through May 12 th , 2020 study...
Valvular heart disease is an important contributor to cardiovascular morbidity and mortality remains underdiagnosed. Deep learning analysis of electrocardiography (ECG) may be useful in detecting aortic stenosis (AS), regurgitation (AR), mitral (MR). This study aimed develop ECG deep algorithms identify moderate or severe AS, AR, MR alone combination. A total 77,163 patients undergoing within 1 year before echocardiography from 2005-2021 were identified split into train (n = 43,165),...
BackgroundFor patients with asymptomatic severe aortic stenosis and preserved left ventricular ejection fraction, current guidelines recommend routine clinical surveillance every 6 to 12 months. Data from randomized trials examining whether early intervention transcatheter aortic-valve replacement (TAVR) will improve outcomes in these are lacking.MethodsAt 75 centers the United States Canada, we randomly assigned, a 1:1 ratio, undergo TAVR transfemoral placement of balloon-expandable valve...
This study examined the effects of intracoronary irradiation on neointimal proliferation after overstretch balloon angioplasty in a normolipemic swine model restenosis.Restenosis percutaneous transluminal coronary represents, part, proliferative response vascular smooth muscle at site injury. We have previously shown that ionizing radiation, delivered by means an source, causes focal medial fibrosis. therefore hypothesized time might impair restenosis process.Nineteen juvenile underwent...
Suggestions that there is a growing epidemic of suicide among college students in the United States are false. The National Survey Counseling Center Directors reports 1,404 student suicides over 14-year period and an adjusted rate 6.5, half general US population (12.6 for all races) during this when matched gender age. centers appear effective treating suicidal students, although who were currently or previously clients at campus counseling 3 times other have 18 risk compared to general....
Abstract Background and Aims Early identification of cardiac structural abnormalities indicative heart failure is crucial to improving patient outcomes. Chest X-rays (CXRs) are routinely conducted on a broad population patients, presenting an opportunity build scalable screening tools for Stage B or worse with deep learning methods. In this study, model was developed identify severe left ventricular hypertrophy (SLVH) dilated ventricle (DLV) using CXRs. Methods A total 71 589 unique CXRs...
Osmotic blood-brain barrier (BBB) disruption induced by intraarterial infusion of mannitol is used in conjunction with chemotherapy to treat human brain tumors. The time course closure, or the so-called therapeutic window, has been examined animals but little information available humans. authors, therefore assessed closure after osmotic BBB humans.Disruption was demonstrated using 99mTc-glucoheptonate (TcGH) single-photon emission computerized tomography (SPECT) scanning 12 patients who...
:Restenosis after percutaneous transluminal coronary angioplasty represents, in part, a proliferative response of vascular smooth muscle at teh site injury. We have previously shown that high-dose radiation (20 Gy), delivered via an intracoronary 192Ir source, causes focal medial fibrosis and markedly impairs the restenosis process balloon swine. This study sought to delineate dose-response characteristics this effect. : Forty juvenile swine underwent angiography; segment left artery was...
<h3>Importance</h3> The incidence of sudden cardiac death is higher in US basketball players compared with other athlete groups. However, the recognition risk for among challenging because little known regarding athletic remodeling these athletes or similarly increased size. <h3>Objective</h3> To perform a comprehensive structural analysis National Basketball Association (NBA) professional athletes. <h3>Design, Setting, and Participants</h3> Echocardiographic observational study NBA on...
<h3>Importance</h3> Critical illness, a marked inflammatory response, and viruses such as SARS-CoV-2 may prolong corrected QT interval (QTc). <h3>Objective</h3> To evaluate baseline QTc on 12-lead electrocardiograms (ECGs) ensuing changes among patients with without COVID-19. <h3>Design, Setting, Participants</h3> This cohort study included 3050 aged 18 years older who underwent testing had ECGs at Columbia University Irving Medical Center from March 1 through May 1, 2020. Patients were...