A5073029210- Blood Pressure and Hypertension Studies
- Heart Rate Variability and Autonomic Control
- Cardiac Health and Mental Health
- Cardiovascular Health and Disease Prevention
- Cardiovascular Health and Risk Factors
- Sodium Intake and Health
- Nutritional Studies and Diet
- Hemodynamic Monitoring and Therapy
- Cardiovascular Syncope and Autonomic Disorders
- Medication Adherence and Compliance
- Health Systems, Economic Evaluations, Quality of Life
- Climate Change and Health Impacts
- Cardiac Imaging and Diagnostics
- Hormonal Regulation and Hypertension
- Lipoproteins and Cardiovascular Health
- Cardiovascular and exercise physiology
- Cardiovascular Function and Risk Factors
- Genetic Associations and Epidemiology
- Heart Failure Treatment and Management
- Stress Responses and Cortisol
- Cardiovascular Disease and Adiposity
- Health, Environment, Cognitive Aging
- Acute Myocardial Infarction Research
- Health disparities and outcomes
- Pulmonary Hypertension Research and Treatments
Columbia University Irving Medical Center
2016-2025
Columbia University
2015-2024
University of Mississippi Medical Center
2016-2021
Royal College of Physicians
2007-2021
Jackson Memorial Hospital
2016-2020
University of Alabama at Birmingham
2010-2020
University of Virginia
2020
Kaiser Permanente San Francisco Medical Center
2020
Northwestern University
2013-2019
University of Utah
2016-2017
Recent data suggest that visit-to-visit variability of blood pressure is associated with stroke incidence. Correlates increased in and the relationship between all-cause mortality were examined using on US adults ≥ 20 years age from Third National Health Nutrition Examination Survey (n = 956). Three consecutive readings taken during 3 separate study visits 1988 to 1994. Based mean second third measurements each visit, for participant was defined standard deviation coefficient variation...
Little is known regarding the association between level of blood pressure (BP) in young adulthood and cardiovascular disease (CVD) events by middle age.To assess whether adults who developed hypertension, defined 2017 American College Cardiology (ACC)/American Heart Association (AHA) BP guideline, before age 40 years have higher risk for CVD compared with those maintained normal BP.Analyses were conducted prospective cohort Coronary Artery Risk Development Young Adults (CARDIA) study,...
The diagnosis and management of hypertension, a common cardiovascular risk factor among the general population, have been based primarily on measurement blood pressure (BP) in office. BP may differ considerably when measured office outside setting, higher out-of-office is associated with increased independent BP. Self-measured monitoring, by an individual at home, validated approach for measurement. Several national international hypertension guidelines endorse self-measured monitoring....
Asian Americans (AsA), Native Hawaiians, and Pacific Islanders (NHPI) comprise 7.7% of the U.S. population, AsA have had fastest growth rate since 2010. Yet National Institutes Health (NIH) has invested only 0.17% its budget on NHPI research between 1992 2018. More than 40 ethnic subgroups are included within (with no majority subpopulation), which highly diverse culturally, demographically, linguistically, socioeconomically. However, data for these groups often aggregated, masking critical...
Basic science research suggests a causal role for endothelial dysfunction in chronic obstructive pulmonary disease (COPD). Clinical studies examining function are lacking, particularly early the disease. Flow-mediated dilation (FMD) is physiologic measure of reactivity to endogenous nitric oxide.We hypothesized that lower FMD among former smokers would be associated with post-bronchodilator FEV(1), higher percentage emphysema using computed tomography (CT) and diffusing capacity.We measured...
Accumulating evidence suggests that increased visit-to-visit variability (VVV) of blood pressure is associated with stroke. No study has examined the association between VVV and stroke in postmenopausal women, scarce data exist as to whether this relation independent temporal trend pressure. We 58228 women enrolled Women's Health Initiative. Duplicate readings, which were averaged, taken at baseline each annual visit. was defined SD for participant's mean systolic (SBP) across visits (SD)...
Refractory hypertension is an extreme phenotype of antihypertensive treatment failure. Participants in the REasons for Geographic And Racial Differences Stroke (REGARDS) Study, a large (n=30 239), population-based cohort were evaluated to determine prevalence refractory and associated cardiovascular risk factors comorbidities. was defined as uncontrolled blood pressure (systolic/diastolic, ≥140/90 mm Hg) on ≥5 drug classes. with resistant Hg ≥3 or <140/90 ≥4 classes) all participants...
<h3>Context</h3> Depression consistently predicts recurrent events and mortality in patients with acute coronary syndrome (ACS), but it has 2 core diagnostic criteria distinct biological correlates—depressed mood anhedonia (loss of pleasure or interest). <h3>Objective</h3> To determine if depressed and/or predict 1-year medical outcomes for ACS. <h3>Design</h3> Observational cohort study post-ACS hospitalized between May 2003 June 2005. Within 1 week admission, underwent a structured...
Pulmonary arterial hypertension (PAH) is a progressive disease that causes exercise limitation, heart failure, and death. We aimed to determine the safety efficacy of aspirin simvastatin in PAH.We performed randomized, double-blind, placebo-controlled 2×2 factorial clinical trial patients with PAH receiving background therapy at 4 centers. A total 92 were be randomized 81 mg or matching placebo 40 placebo. The primary outcome was 6-minute walk distance 6 months. Sixty-five subjects had been...
OBJECTIVE New clinical practice recommendations include A1C as an alternative to fasting glucose a diagnostic test for identifying pre-diabetes. The impact of these new on the diagnosis pre-diabetes is unknown. RESEARCH DESIGN AND METHODS Data from National Health and Nutrition Examination Survey 1999–2006 (n = 7,029) were analyzed determine percentage number U.S. adults without diabetes classified having by elevated (5.7–6.4%) impaired (IFG) (fasting 100–125 mg/dl) criterion separately....
Basic research implicates alveolar endothelial cell apoptosis in the pathogenesis of chronic obstructive pulmonary disease (COPD) and emphysema. However, information on microparticles (EMPs) mild COPD emphysema is lacking. We hypothesized that levels CD31(+) EMPs phenotypic for would be elevated associated with percent computed tomography (CT). Associations microvascular blood flow (PMBF), diffusing capacity, hyperinflation were also examined. The Multi-Ethnic Study Atherosclerosis recruited...