- Cardiac Valve Diseases and Treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Infective Endocarditis Diagnosis and Management
- Aortic Disease and Treatment Approaches
- Cardiac and Coronary Surgery Techniques
- Aortic aneurysm repair treatments
- Cardiac Structural Anomalies and Repair
- Infectious Aortic and Vascular Conditions
- Kawasaki Disease and Coronary Complications
- Anesthesia and Sedative Agents
- Electrospun Nanofibers in Biomedical Applications
- Surgical Simulation and Training
- Vascular Procedures and Complications
- Mechanical Circulatory Support Devices
- Abdominal vascular conditions and treatments
- Intensive Care Unit Cognitive Disorders
- Orthopedic Infections and Treatments
- Coronary Interventions and Diagnostics
- Antiplatelet Therapy and Cardiovascular Diseases
- Platelet Disorders and Treatments
- Heart Failure Treatment and Management
- Congenital Heart Disease Studies
- Tracheal and airway disorders
- Esophageal and GI Pathology
- Diversity and Career in Medicine
University Medical Center Freiburg
2023-2024
University of Freiburg
2024
Royal Brompton & Harefield NHS Foundation Trust
2020-2024
Universitäts-Herzzentrum Freiburg-Bad Krozingen
2024
Royal Brompton Hospital
2021-2023
Guy's and St Thomas' NHS Foundation Trust
2021-2023
Imperial College London
2023
St. Thomas Hospital
2023
St Thomas' Hospital
2023
Harefield Hospital
2020-2022
Abstract Background Rapid-deployment aortic valve replacement (RDAVR) is an alternative to conventional AVR (cAVR) for stenosis. Benefits include a reduction in operative times, facilitation of minimal access surgery and superior haemodynamics compared valves. However, further evidence required inform guidelines, preferably the form propensity-matched studies that mid-term follow-up data. Methods This was single-centre, retrospective, cohort study comparing Perceval Perimount Magna Ease...
The purpose was to assess predictors of early silent graft failure prior discharge by multislice computed tomography in patients after off-pump coronary artery bypass grafting.From January 2017 until April 2018, 192 tomographic scans consecutive asymptomatic were performed (seventh postoperative day ± 4 days) and analysed retrospectively. In total, 359 arterial 278 venous anastomoses evaluated. Two patient groups (overall patent versus at least 1 occluded anastomosis) compared....
Abstract Objective This retrospective study aimed to compare the outcomes of sutureless aortic valve replacement (su-AVR) and conventional bioprosthetic sutured AVR (cAVR) in high-risk patients undergoing redo surgery. Methods A total 79 who underwent between 2014 2021 were included study. Of these, 27 su-AVR 52 cAVR. Patient characteristics clinical analysed using multivariate regression Kaplan Meier survival test. Results The groups similar terms age, gender, left ventricular function,...
Infections are a major setback of vascular reconstruction and associated with considerable morbidity mortality. We evaluated retrospectively our results self-made bovine pericardial grafts in infected vessel revascularization versus standard graft material.Retrospective analysis 9 patients 10 miscellaneous (vein, homograft) for infections.Infection-free rate the group was 100% 17 months. For after reconstructions grafts, infection-free 82% 45 Overall in-hospital mortality 10.5%. There were...
The increasing complexity of surgical patients and working time constraints represent challenges for training. In this study, the European Association Cardio-Thoracic Surgery Residents' Committee aimed to evaluate satisfaction with current training programmes across Europe.We conducted an online survey between October 2018 April 2019, completed by a total 219 participants from 24 countries.The average respondent was in fourth or fifth year training, mostly on cardiac surgery pathway. Most...
This study aimed to provide comprehensive morphological descriptions of the morphology tricuspid valve and evaluate if a novel echocardiography-based nomenclature can also be understood anatomically.
Abstract Background Mesenteric ischemia is associated with poor outcome and high overall mortality. The aim was to analyze an interdisciplinary treatment approach of vascular visceral specialists focusing on the in-hospital follow-up in patients acute acute-on-chronic mesenteric ischemia. Methods From 2010 until 2017, 26 consecutive or chronic were treated by team. Data prospectively collected retrospectively evaluated. Throughout initial examination, extent bowel resection determined...
Across Europe there are significant variations in the fundamental structure and content of cardiothoracic surgery (CTS) training programmes. Previous efforts have been made to introduce a Unified European Training System, which outlined fundamentals ideal programme supported paradigm shift from an apprenticeship competency-based model. This article's goal was define key structural, administrative executive details such lay foundations for standardization surgical across Europe.The...
Dexmedetomidine (DEX) is a highly selective α-2 agonist with many desirable effects including analgesia, improvement of hemodynamic stability, and potential myocardial renal protection. The aim this study was to investigate the effect DEX on patients undergoing off-pump coronary artery bypass (OPCAB) grafting regard less pain medication, earlier extubation, faster transfer normal ward, cardiac From January 2012 March 2015, 464 receiving OPCAB were included for retrospective analysis. After...
Lipopolysaccharide (LPS) induced inflammation often leads to lung injury, in which pulmonary recruitment of neutrophils plays a pivotal role. Inflammatory processes are influenced by CD26/DPP4, highly expressed lungs. Asthma CD26/DPP4 deficient (CD26/DPP4⁻) Fischer (F) 344 rats suffering from transport block the rER caused point mutation showed reduced and expression immunomodulating surfactant proteins (SP). The degree LPS injury has not been investigated so far.We hypothesize that only an...
Background Tricuspid regurgitation (TR) in patients undergoing surgery for mitral valve (MV) increases morbidity and mortality, especially case of a poor right ventricle. Does repair mild-to-moderate insufficiency the tricuspid (TV) MV lead to benefit early postoperative outcome? Methods A total 22 with TR underwent concomitant TV Tri-Ad (Medtronic ATS Medical Inc., Minneapolis, Minnesota, United States) Edwards Cosgrove (Edwards Lifesciences Irvine, California, rings. The severity was...
The choice of a suitable vascular graft in infected anatomic sites can be demanding and is still an area discussion. When urgent repair needed no appropriate autologous veins are available, self-made bovine grafts viable option. We present possible solution for the technical aspects reconstruction by pericardial Y aortic primary aortoenteric fistula.
Sonoclot is used to measure kaolin-based activated clotting time (kACT) for heparin management. Apart from measuring kACT, the device assesses patient's coagulation status by glass bead-activated tests (gbACTs; also clot rate [CR] and platelet function [PF]). Recently, a new version of has been released, redesign may result in performance changes. The aim this study was evaluate compare (S2) previous (S1) Sonoclot.The S1 routine management 30 patients undergoing elective cardiac surgery....
Electrosurgery is fundamental to the precise, fast and bloodless preparation of internal thoracic artery grafts in cardiac surgery. The PEAK PlasmaBlade a monopolar electrosurgical device that uses pulsed radiofrequency energy generate plasma-mediated discharge along an insulated electrode, creating cutting edge while blade stays near body temperature. aim this study compare histological samples, computed-tomography graft patency, clinical outcomes patients after off-pump coronary bypass...
During the COVID-19 pandemic, performing a surgeon's duties has become challenging while adhering to social distancing mandates. To aid in continuity of healthcare services, rapid implementation digital communication tools became necessity. This is an account experiences using platforms, namely Microsoft Teams and Zoom, for clinical educative purposes field Cardiothoracic Surgery UK. While enabling ongoing virtual meetings, conferences learning opportunities residents with little...
Abstract Objectives Thrombocytopenia following Perceval aortic valve replacement has been described previously with variable outcome. Studies have lacked a robust analysis of platelet fluctuation and factors affecting it. We aimed to statistically describe the trend in thrombocyte variability as compared conventional replacement, assess predictors well impact on associated outcomes. Methods One hundred consecutive patients first-time were retrospectively 219 after Perimount Magna Ease...