Kintur Sanghvi

ORCID: 0000-0003-2981-7885
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About
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Research Areas
  • Vascular Procedures and Complications
  • Peripheral Artery Disease Management
  • Blood Pressure and Hypertension Studies
  • Venous Thromboembolism Diagnosis and Management
  • Coronary Interventions and Diagnostics
  • Acute Myocardial Infarction Research
  • Cardiac Valve Diseases and Treatments
  • Renal and Vascular Pathologies
  • Hemodynamic Monitoring and Therapy
  • Infective Endocarditis Diagnosis and Management
  • Cardiovascular Health and Disease Prevention
  • Aortic aneurysm repair treatments
  • Central Venous Catheters and Hemodialysis
  • Heart Rate Variability and Autonomic Control
  • Cardiac Imaging and Diagnostics
  • Cerebrovascular and Carotid Artery Diseases
  • Cardiac Structural Anomalies and Repair
  • Cardiac, Anesthesia and Surgical Outcomes
  • Health Literacy and Information Accessibility
  • Sodium Intake and Health
  • Congenital Heart Disease Studies
  • Social Media in Health Education
  • Cardiac Arrhythmias and Treatments
  • Pharmaceutical industry and healthcare
  • Diagnosis and Treatment of Venous Diseases

Deborah Heart and Lung Center
2014-2023

Virtua Health
2023

Johnston Memorial Hospital
2022

Lung Institute
2012-2020

John Wiley & Sons (United States)
2016

Philadelphia College of Osteopathic Medicine
2015

Commonwealth Medical College
2010

Catholic Medical Center
2008

10.1016/s0140-6736(18)31082-1 article EN The Lancet 2018-05-23

10.1016/s0140-6736(21)00788-1 article EN The Lancet 2021-05-16
Michel Azizi Manish Saxena Yale Wang J. Stephen Jenkins Chandan Devireddy and 95 more Florian Rader Naomi D.L. Fisher Roland E. Schmieder Felix Mahfoud Jason B. Lindsey Kintur Sanghvi Thomas M. Todoran John Pacella John M. Flack Joost Daemen Andrew Sharp Philipp Lurz Michael J. Bloch Michael A. Weber Melvin D. Lobo Jan Basile Lisa Claude Helen Reeve-Stoffer Candace K. McClure Ajay J. Kirtane Christopher M. Mullin Candace K. McClure Lisa Thackeray Yongshi Wang Glenn M. Chertow Venita Chandra Harold Dauerman Thomas Kahan Steven Ullery Nirat Beohar Ozgen Dogan M Mokrzycki Scott Mullaney Björn Redfors Huseng Vefali Andreas Loening Ron Zagoria Nedaa Skeik Richard Bae Amy McMeans JoAnne Goldman Rose Peterson Isabelle Tutor Michael R. Harrison Angel Penning Janice P. Lea Amanda Fiebach Claudia Merlin Suhail Dohad Anne H. Tran Kirin Bhatia Piotr Sobieszczyk Ian Halliday Tay Munson Steven B. Laster Mathew Bunte Anthony R Hart Dana E. King Jamie Hall Courtney Krathen Luot Lewis Ashley Willitts Anthony Awkar Casey Palmer Anna Tecklenburg John Schindler Matthew F. Muldoon MaryJo Albright Tracy L. Nicholson Youseff Chami Abdul Moiz Hafiz Emily Starkey Kristal Adams Nelson L. Bernardo Judith H. Veis Hayder Hashim Suman Singh Donna Whitman Rick Stouffer Alan L. Hinderliter Meghan Allen Tatum Scholl Pete Fong James S. Gainer Sherron Crook Ellen Hatchcock Debbie L. Cohen Jay Giri Taisei Kobayashi Robin Neubauer Suveeksha Naidu Jai Radhakrishnan Candido Batres Suzanne Edwards Matheen Khuddus

Importance Two initial sham-controlled trials demonstrated that ultrasound renal denervation decreases blood pressure (BP) in patients with mild to moderate hypertension and is resistant treatment. Objective To study the efficacy safety of without confounding influence antihypertensive medications hypertension. Design, Setting, Participants Sham-controlled, randomized clinical trial outcome assessors blinded treatment assignment was conducted between January 14, 2019, March 25, 2022, at 37...

10.1001/jama.2023.0713 article EN JAMA 2023-02-28

Ultrasound renal denervation (uRDN) was shown to lower blood pressure (BP) in patients with uncontrolled hypertension (HTN). Establishing the magnitude and consistency of uRDN effect across HTN spectrum is clinically important.

10.1001/jamacardio.2023.0338 article EN cc-by-nc-nd JAMA Cardiology 2023-02-28

The radial approach to angiography and intervention has emerged internationally as the preferred alternative traditional femoral 1. Multiple observational randomized trials performed date have shown an association between access reduced risk for bleeding vascular complications 2. Other studies costs 3, increased patient satisfaction 4, 5, mortality in high-risk subgroups like those with ST-segment elevation myocardial infarction (STEMI) 6. Disadvantages include radiation exposure operator...

10.1002/ccd.25209 article EN Catheterization and Cardiovascular Interventions 2013-10-12
Michel Azizi Roland E. Schmieder Felix Mahfoud Michael A. Weber Joost Daemen and 95 more Melvin D. Lobo Andrew S.P. Sharp Michael J. Bloch Jan Basile Yale Wang Manish Saxena Philipp Lurz Florian Rader Jeremy Sayer Naomi D.L. Fisher David Fouassier Neil C. Barman Helen Reeve-Stoffer Candace K. McClure Ajay J. Kirtane Desmond Jay Nedaa Skeik Robert S. Schwartz Suhail Dohad Ronald G. Victor Kintur Sanghvi Josh Costello Courtney Walsh Josephine Abraham Theophilus Owan Anu Abraham Laura Mauri Piotr Sobieszczky Jonathan S. Williams Chanwit Roongsritong Thomas M. Todoran Eric R. Powers Emily Hodskins Pete Fong Cheryl L. Laffer James S. Gainer Mark Robbins John P. Reilly Michael Cash Jessie Goldman Sandeep Aggarwal Gary S. Ledley David His Scott D. Martin Edward L. Portnay David A. Calhoun Thomas McElderry William Maddox Suzanne Oparil Pei-Hsiu Huang Powell Jose Matheen Khuddus Suzanne Zentko James O’Meara Ilie Barb Joseph M. Garasic Doug Drachman Randy Zusman Kenneth Rosenfield Chandan Devireddy Janice P. Lea Bryan Wells Rick Stouffer Alan L. Hinderliter Eric Pauley Srinivasa Potluri Scott Biedermann Sripal Bangalore Stephen Williams David Zidar Mehdi H. Shishehbor Barry Effron Marco Costa Jai Radhakrishnan Anthony Mathur Ajay Jain Sudha Ganesh Iyer Nicholas Robinson Sadat Ali Edroos Terry Levy Amit Patel David Beckett Clare Bent Justin E. Davies Neil Chapman Matthew Shun Shin James P. Howard Anil Joseph Richard D’Souza Robert Gerber Mohamad Faris Andrew John Marshall Cristina Elorz Robert Höllriegel Karl Fengler

Background: The multicenter, international, randomized, blinded, sham-controlled RADIANCE-HTN SOLO trial (A Study of the ReCor Medical Paradise System in Clinical Hypertension) demonstrated a 6.3 mm Hg greater reduction daytime ambulatory systolic blood pressure (BP) at 2 months by endovascular ultrasound renal denervation (RDN) compared with sham procedure among patients not treated antihypertensive medications. We report 6-month results after addition recommended standardized stepped-care...

10.1161/circulationaha.119.040451 article EN Circulation 2019-03-17

Abstract Background: Radial artery access for transradial catheterization is obtained using either Seldinger or modified technique. There no comparative evaluation of the safety and benefits these two techniques. Methods: Four hundred twelve patients undergoing were randomized to group I ( n = 210) technique, II 202) Demographic procedural data collected at time procedure. Data on hematoma radial occlusion (RAO) recorded 24 hr 30 days after Results: Age, gender, weight, height, history...

10.1002/ccd.23445 article EN Catheterization and Cardiovascular Interventions 2012-03-14
Michel Azizi Felix Mahfoud Michael A. Weber Andrew Sharp Roland E. Schmieder and 95 more Philipp Lurz Melvin D. Lobo Naomi D.L. Fisher Joost Daemen Michael J. Bloch Jan Basile Kintur Sanghvi Manish Saxena Philippe Gosse J. Stephen Jenkins Terry Levy Alexandre Persu Benjamin Kably Lisa Claude Helen Reeve-Stoffer Candace K. McClure Ajay J. Kirtane Christopher M. Mullin Lisa Thackeray Glenn M. Chertow Thomas Kahan Harold Dauerman Steven Ullery J. Dawn Abbott Andreas Loening Ron Zagoria John Costello Courtney Krathan Luot Lewis Andrew McElvarr John P. Reilly Michael Cash Shannon Williams Maria Jarvis Pete Fong Cheryl L. Laffer James S. Gainer Mark Robbins Sherron Crook Sarita Maddel David H. Hsi Scott D. Martin Edward L. Portnay Maryanne Ducey Suzanne Rose Elizabeth DelMastro Sripal Bangalore Stephen Williams Stanley Cabos Carolina Rodríguez Álvarez Thomas M. Todoran Eric R. Powers Emily Hodskins Vijay Paladugu Anna Tecklenburg Chandan Devireddy Janice P. Lea Bryan Wells Amanda Fiebach Claudia Merlin Florian Rader Suhail Dohad H. Mike Kim Mohammad H. Rashid Josephine Abraham Theophilus Owan Anu Abraham Iran Lavasani Hailey Neilson David A. Calhoun Thomas McElderry William Maddox Suzanne Oparil Sheila Kinder Jai Radhakrishnan Candido Batres Suzanne Edwards Joseph M. Garasic Doug Drachman Randy Zusman Kenneth Rosenfield Danny Do Matheen Khuddus Suzanne Zentko James O’Meara Ilie Barb Abby Foster Alice Boyette Yale Wang Desmond Jay Nedaa Skeik Robert S. Schwartz Rose Peterson Jo Anne Goldman Jessie Goldman

Importance Although early trials of endovascular renal denervation (RDN) for patients with resistant hypertension (RHTN) reported inconsistent results, ultrasound RDN (uRDN) was found to decrease blood pressure (BP) vs sham at 2 months in RHTN taking stable background medications the Study ReCor Medical Paradise System Clinical Hypertension (RADIANCE-HTN TRIO) trial. Objectives To report prespecified analysis persistence BP effects and safety uRDN 6 conjunction escalating antihypertensive...

10.1001/jamacardio.2022.3904 article EN cc-by-nc-nd JAMA Cardiology 2022-11-09
Michel Azizi Andrew S.P. Sharp Naomi D.L. Fisher Michael A. Weber Melvin D. Lobo and 95 more Joost Daemen Philipp Lurz Felix Mahfoud Roland E. Schmieder Jan Basile Michael J. Bloch Manish Saxena Yale Wang Kintur Sanghvi J. Stephen Jenkins Chandan Devireddy Florian Rader Philippe Gosse Lisa Claude Dimitri A. Augustin Candace K. McClure Ajay J. Kirtane Yale Wang Nedaa Skeik Richard Bae Amy McMeans JoAnne Goldman Rose Peterson J. Stephen Jenkins Isabelle Tutor Michael R. Harrison Angel Penning Chandan Devireddy Janice P. Lea Amanda Fiebach Claudia Merlin Florian Rader Suhail Dohad Anne H. Tran Kirin Bhatia Naomi D.L. Fisher Piotr Sobieszczyk Ian Halliday Tay Munson Jason B. Lindsey Steven B. Laster Mathew Bunte Anthony R Hart Dana E. King Jamie Hall Kintur Sanghvi Courtney Krathen Luot Lewis Ashley Willitts Thomas M. Todoran Jan Basile Anthony Awkar Casey Palmer Anna Tecklenburg John Schindler John Pacella Matthew F. Muldoon MaryJo Albright Tracy L. Nicholson John M. Flack Youseff Chami Abdul Moiz Hafiz Emily Starkey Kristal Adams Nelson L. Bernardo Judith H. Veis Hayder Hashim Suman Singh Donna Whitman Rick Stouffer Alan L. Hinderliter Meghan Allen Tatum Scholl Pete Fong James S. Gainer Sherron Crook Ellen Hatchcock Debbie L. Cohen Jay Giri Taisei Kobayashi Robin Neubauer Suveeksha Naidu Ajay J. Kirtane Jai Radhakrishnan Candido Batres Suzanne Edwards Matheen Khuddus Suzanne Zentko Abby Touchton Marti Roberson Michael J. Bloch Abhilash Akinapelli Lisa English Bridget Neumann Farrel Mendelsohn

BACKGROUND: The randomized, sham-controlled RADIANCE-HTN (A Study of the Recor Medical Paradise System in Clinical Hypertension) SOLO, TRIO, and RADIANCE II Stage trials independently met their primary end point a greater reduction daytime ambulatory systolic blood pressure (SBP) 2 months after ultrasound renal denervation (uRDN) patients with hypertension. To characterize longer-term effectiveness safety uRDN versus sham at 6 months, blinded addition antihypertensive treatments (AHTs), we...

10.1161/circulationaha.123.066941 article EN Circulation 2023-10-26

Background: Adjunctive coronary atherectomy (CA) can be utilized in treating severely calcified lesions; however, the temporal trends, patient selection, and variation use of CA have not been well described. We sought to assess trends usage, interhospital variability, outcomes with among patients undergoing percutaneous intervention (PCI). Methods: All PCI National Cardiovascular Data Registry CathPCI from July 1, 2009 December 31, 2016 (N=3 864 377) were analyzed based on utilization either...

10.1161/circinterventions.119.008239 article EN Circulation Cardiovascular Interventions 2020-01-24

Percutaneous intervention of iliac artery (IA) and superficial femoral (SFA) disease is often performed via ipsilateral or contralateral access. However, this approach may be difficult in patients with severe common atherosclerosis, morbid obesity, conditions prohibiting prolonged bed rest. transradial coronary has gained popularity due to the low frequency access site complications, early ambulation, perhaps cost savings discharge. Transradial (TRI) IA SFA been previously described only...

10.1111/j.1540-8183.2008.00384.x article EN Journal of Interventional Cardiology 2008-08-14

The objective of this study was to compare door-to-balloon times and other variables in ST-segment elevation myocardial infarction (STEMI) patients undergoing primary percutaneous coronary intervention (PCI) using transfemoral or transradial approaches.Transradial PCI has been shown lower the risk access site complications but procedure is not applied STEMI patients, due concerns procedural complexity adversely affecting prompt reperfusion. There paucity real-world data comparing TRI with...

10.1002/ccd.22425 article EN Catheterization and Cardiovascular Interventions 2010-01-25

Abstract The blood pressure (BP) lowering response to renal denervation (RDN) remains variable with about one-third of patients not responding ultrasound or radiofrequency RDN. Identification predictors the BP RDN is needed optimize patient selection for this therapy. This a post-hoc analysis RADIANCE-HTN SOLO study. was measured by change in daytime ambulatory systolic (dASBP) at 2 months post procedure. Univariate regression used initially assess potential outcome followed multivariate...

10.1038/s41371-021-00547-y article EN cc-by Journal of Human Hypertension 2021-05-24

We report a technique for retrieval of broken angioplasty wire fragment from the coronary system using more simplified that does not involve use snare or any other tool. With an additional and balloon catheter, we could safely remove circulation in very short time. Cathet. Cardiovasc. Intervent. 51:483–486, 2000. © 2000 Wiley-Liss, Inc.

10.1002/1522-726x(200012)51:4<483::aid-ccd24>3.0.co;2-f article EN Catheterization and Cardiovascular Interventions 2000-01-01

Supporting catheters in percutaneous stenting of anatomically difficult coronary lesions are utilized by interventional cardiologists. The GuideZilla guide extension catheter is designed for deep seating arteries to provide extra guidance support equipment delivery during interventions or coaxial alignment tortuous vessels. There limited GuideZilla-related complications reported the literature. We present a challenging case left main and anterior descending artery dissection, complicated...

10.1016/j.ihj.2015.04.018 article EN publisher-specific-oa Indian Heart Journal 2015-05-23

The human immunodeficiency virus (HIV) can cause diverse cardiovascular complications. In HIV patients on antiretroviral therapy, the prevalence of myocardial infarction has steadily increased over years. Young who are naïve to therapy and experience coronary events not well represented in medical literature. We describe case a 22-year-old man, infected with for 4 years never treated emergently presented non-ST-segment-elevation infarction. Coronary angiograms revealed thrombosis multiple...

10.14503/thij-13-3160 article EN Texas Heart Institute Journal 2014-04-01

To assess the variability of renal artery (RA) anatomy and presence RA-pathology in patients with mild-to-moderate hypertension enrolled RADIANCE-HTN SOLO trial.RADIANCE-HTN was a multicenter, international, blinded, randomized, sham-controlled trial evaluating ultrasound-based endovascular denervation (RDN) while off antihypertensive medications.Eligible subjects had pre-randomization CT- or MR- angiography (CTA, MRA) to confirm anatomic suitability define RA ablation sites. All images were...

10.1016/j.carrev.2021.09.008 article EN cc-by-nc-nd Cardiovascular revascularization medicine 2021-09-30

We report a case of percutaneous closure congenital perimembranous ventricular septal defect (VSD) performed via radial artery and basilic vein accesses. further discuss the technique, advantages, limitation this innovative approach for VSD . (J Interven Cardiol 2014;27:199–203)

10.1111/joic.12098 article EN Journal of Interventional Cardiology 2014-02-11
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