- Blood Pressure and Hypertension Studies
- Cardiac Ischemia and Reperfusion
- Anesthesia and Neurotoxicity Research
- Cardiac Structural Anomalies and Repair
- Cardiac Arrest and Resuscitation
- Assisted Reproductive Technology and Twin Pregnancy
- Tissue Engineering and Regenerative Medicine
- Atrial Fibrillation Management and Outcomes
- Hemodynamic Monitoring and Therapy
- Cardiovascular Health and Disease Prevention
- Cardiovascular Issues in Pregnancy
- Connective tissue disorders research
- Cardiac tumors and thrombi
- Social Media in Health Education
- Medical Imaging and Pathology Studies
- Pericarditis and Cardiac Tamponade
- Restraint-Related Deaths
- Coronary Artery Anomalies
- Coronary Interventions and Diagnostics
- Advanced MRI Techniques and Applications
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Heart Rate Variability and Autonomic Control
- Pleural and Pulmonary Diseases
- Sodium Intake and Health
- Cardiac pacing and defibrillation studies
Radiance Technologies (United States)
2023
Luton and Dunstable Hospital
2022
Luton and Dunstable University Hospital NHS Foundation Trust
2021
St. James's Hospital
2020
Creative Research Enterprises (United States)
2017
Essex Cardiothoracic Centre
2017
Princess Alexandra Hospital NHS Trust
2015-2016
Glenfield Hospital
2012
University of Leicester
2012
University of Warwick
2004-2005
Background: The multicenter, international, randomized, blinded, sham-controlled RADIANCE-HTN SOLO trial (A Study of the ReCor Medical Paradise System in Clinical Hypertension) demonstrated a 6.3 mm Hg greater reduction daytime ambulatory systolic blood pressure (BP) at 2 months by endovascular ultrasound renal denervation (RDN) compared with sham procedure among patients not treated antihypertensive medications. We report 6-month results after addition recommended standardized stepped-care...
The COVID-19 pandemic is a highly contagious viral illness which conventionally manifests primarily with respiratory symptoms. We report case whose first manifestation of was pericarditis, in the absence symptoms, without any serious complications. Cardiac involvement various forms possible COVID-19. present where classic signs or only evident disease. This highlights an atypical presentation and need for high index suspicion to allow early diagnosis limit spread by isolation.
Abstract Background Spontaneous coronary artery dissection (SCAD) is a recognized cause of acute syndrome (ACS). Pregnancy, the postpartum period, and illicit drug use have all been reported as potential triggers. Case summary We describe case 41-year-old patient who presented to emergency department with chest pain in setting recent cocaine amphetamine use. The was 4 months following an uncomplicated pregnancy. Past medical history non-contributory, no known risk factors for ischaemic heart...
Remote ischaemic conditioning (RIC) protects against ischaemia-reperfusion injury, but it is unclear whether could also attenuate adverse cardiac remodelling post-MI. We hypothesised that RIC generates a blood born signal capable of reducing the hypertrophic response by modulating gene expression associated with remodelling. Superfusate was collected from conditioned Langendorff perfused rat hearts (RIC-superfusate). Blood taken healthy volunteers after three cycles upper arm (RIC-serum)....
This study assessed the cardio- and renoprotective effect of remote ischemic Preconditioning (PreC) in patients undergoing percutaneous coronary intervention (PCI). Myocyte necrosis contrast induced nephropathy (CIN) occur frequently PCI are associated with subsequent cardiovascular events. Methods: Two hundred consecutive elective normal baseline troponin-I (cTnI) values were recruited. Subjects systematically allocated into 2 groups: 100 received PreC (created by three 5 min inflations a...
<h3>Introduction</h3> Synchronised DC cardioversion is a commonly used treatment option for persistent atrial fibrillation (AF). Atrial distension predisposing factor AF, and fibrosis of the myocardium may prevent remodelling atrium to normalised parameters following cardioversion, with fibrotic begetting inevitable recurrence AF. <h3>Methods</h3> We retrospectively investigated echocardiographic appearances 89 patients prior elective determine whether simple measurements dimensions in...
<h3>Aim</h3> Remote conditioning, whereby intermittent non-critical ischaemia of remote peripheral muscle can protect cardiac from ischaemia-reperfusion (I-R) injury even when applied after the onset ischaemia, has emerged as a potential therapeutic manoeuvre for reducing I-R injury. Whether such protection is mediated via serum factors and whether development impaired in disease states unclear. We sought to develop cell based model assessing injury, utilised this screen sera both control...
We present a case of patient who presented with chest pain, and on diagnostic coronary angiography appeared to have grossly angulated yet significant stenosis.This was proven be an artefactual appearance further assessment intravascular ultrasound imaging.We describe the causes associations tortuosity other arteriopathy, highlight challenges in interpretation tortuous vessels accurately assess luminal narrowing suitability for intervention.We stenosis, its thorough ultrasound.A literature...
P rofessor Keith Goh qualified from the National University of Singapore Medical School in 1985. After completing his basic surgical training, he moved to Prince Wales Hospital Hong Kong 1992 specialise neurosurgery. He later took up a clinical training fellowship at Beth Israel Institute Neurology and Neurosurgery New York, where specialised paediatric wife returned home 1999, two years headed first three operations separate conjoined twins. The second these was unprecedented that it...
A 52 year old man presented to the outpatients' department with dyspnoea, dry cough, and weight loss. The breathlessness had progressed over two years. Also 41 kg of loss in 12 months was concerning. In seeking a cause for this, he underwent bronchoscopy weeks before his appointment, since then rapidly worsened. At consultation unable complete sentence wheelchair. 1. What is main abnormality shown figure? Suggest some causes. 2. would you expect find on examination? immediate...
Professor Keith Goh qualified from the National University of Singapore Medical School in 1985. After completing his basic surgical training, he moved to Prince Wales Hospital Hong Kong 1992 specialise neurosurgery. He later took up a clinical training fellowship at Beth Israel Institute Neurology and Neurosurgery New York, where specialised paediatric wife returned home 1999, two years headed first three operations separate conjoined twins. The second these was unprecedented that it...
A 67-year-old man presented with acute left hemiparesis 6 weeks after pulmonary vein isolation (PVI) for atrial fibrillation. His medical history was notable hypertension and a metallic aortic valve which implanted 23 years previously bicuspid stenosis. He warfarinised his
A 66-year-old woman underwent a pacemaker implantation following symptomatic pause. The lead inadvertently punctured the ventricle during implantation, penetrating through to left internal mammary artery, causing slow hemorrhage. There was subsequent circulatory collapse with shock. We describe this rare yet life-threatening condition. (Level of Difficulty: Intermediate.).
<h3></h3> Coronary artery stents have created the revolutionary field of interventional cardiology. Since their conception in 1964, to first coronary angioplasty performed 1977, multidisciplinary work has made what seemed like incredible and outlandish minimally invasive reopening occlusion into a commonplace mainstay treatment, reducing mortality from cardiovascular disease globally. stent implantation 1986 past 35 years research seen iterative progress. We witnessed ever-evolving design....