David H. Hsi

ORCID: 0000-0002-0914-8947
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About
Contact & Profiles
Research Areas
  • Cardiac Imaging and Diagnostics
  • Cardiovascular Function and Risk Factors
  • Cardiomyopathy and Myosin Studies
  • Cardiac Arrhythmias and Treatments
  • Cardiac Structural Anomalies and Repair
  • Cardiovascular Effects of Exercise
  • Infective Endocarditis Diagnosis and Management
  • Cardiac Valve Diseases and Treatments
  • Cardiac tumors and thrombi
  • Blood Pressure and Hypertension Studies
  • Atrial Fibrillation Management and Outcomes
  • Pericarditis and Cardiac Tamponade
  • Congenital Heart Disease Studies
  • Chemotherapy-induced cardiotoxicity and mitigation
  • Cardiac pacing and defibrillation studies
  • Cardiovascular Disease and Adiposity
  • Cardiac electrophysiology and arrhythmias
  • Hemodynamic Monitoring and Therapy
  • Coronary Artery Anomalies
  • Pulmonary Hypertension Research and Treatments
  • Kawasaki Disease and Coronary Complications
  • Aortic Disease and Treatment Approaches
  • Coronary Interventions and Diagnostics
  • Renal and Vascular Pathologies
  • Acute Myocardial Infarction Research

Stamford Hospital
2016-2024

Columbia University
2017-2024

Bridgeport Hospital
2024

Yale New Haven Hospital
2024

Radiance Technologies (United States)
2022-2023

Royal College of Physicians
2018

Chinese Academy of Medical Sciences & Peking Union Medical College
2017

Fu Wai Hospital
2017

Deborah Heart and Lung Center
2013-2014

Robert Wood Johnson University Hospital
2014

10.1016/s0140-6736(18)31082-1 article EN The Lancet 2018-05-23

10.1016/s0140-6736(21)00788-1 article EN The Lancet 2021-05-16

Patients with hypertrophic obstructive cardiomyopathy (HOCM) and drug-refractory symptoms outflow gradients have limited nonsurgical treatment options. The feasibility of percutaneous intramyocardial septal radiofrequency ablation (PIMSRA) has been reported previously; however, procedural medium-term outcomes are unknown.To describe the safety PIMSRA in a large patient cohort HOCM.This was single-arm, open-label study patients HOCM. presenting to Xijing Hospital Xi'an, China, between October...

10.1001/jamacardio.2022.0259 article EN JAMA Cardiology 2022-03-30

The purpose of this study was to assess the associations between 3-dimensional echocardiography (3DE)-derived changes in right ventricular (RV) volumes and strains with subsequent RV cardiotoxicity patients treated anthracyclines.Although early detection prediction left (LV) dysfunction has been widely studied receiving anthracyclines, little is known about size function population.A total 74 diffuse large B-cell lymphoma who received 6 cycles anthracycline-based treatment were enrolled....

10.1016/j.jaccao.2020.01.007 article EN cc-by-nc-nd JACC CardioOncology 2020-03-01

Background: Immune checkpoint inhibitor (ICI)-associated myocarditis is an uncommon and potentially fatal immune-related adverse event (irAE). Although corticosteroids are recommended as the first-line treatment by current guidelines, patients still have variable responses to it, guidelines vary significantly in terms of strategies. Objectives: In this study, we performed a retrospective analysis ICI-associated our hospital propose new comparative aid individualized treatment. Methods: We...

10.3389/fphar.2021.770631 article EN cc-by Frontiers in Pharmacology 2021-12-06
Michel Azizi Felix Mahfoud Michael A. Weber Andrew Sharp Roland E. Schmieder and 95 more Philipp Lurz Melvin D. Lobo Naomi D.L. Fisher Joost Daemen Michael J. Bloch Jan Basile Kintur Sanghvi Manish Saxena Philippe Gosse J. Stephen Jenkins Terry Levy Alexandre Persu Benjamin Kably Lisa Claude Helen Reeve-Stoffer Candace K. McClure Ajay J. Kirtane Christopher M. Mullin Lisa Thackeray Glenn M. Chertow Thomas Kahan Harold Dauerman Steven Ullery J. Dawn Abbott Andreas Loening Ron Zagoria John Costello Courtney Krathan Luot Lewis Andrew McElvarr John P. Reilly Michael Cash Shannon Williams Maria Jarvis Pete Fong Cheryl L. Laffer James S. Gainer Mark Robbins Sherron Crook Sarita Maddel David H. Hsi Scott D. Martin Edward L. Portnay Maryanne Ducey Suzanne Rose Elizabeth DelMastro Sripal Bangalore Stephen Williams Stanley Cabos Carolina Rodríguez Álvarez Thomas M. Todoran Eric R. Powers Emily Hodskins Vijay Paladugu Anna Tecklenburg Chandan Devireddy Janice P. Lea Bryan Wells Amanda Fiebach Claudia Merlin Florian Rader Suhail Dohad H. Mike Kim Mohammad H. Rashid Josephine Abraham Theophilus Owan Anu Abraham Iran Lavasani Hailey Neilson David A. Calhoun Thomas McElderry William Maddox Suzanne Oparil Sheila Kinder Jai Radhakrishnan Candido Batres Suzanne Edwards Joseph M. Garasic Doug Drachman Randy Zusman Kenneth Rosenfield Danny Do Matheen Khuddus Suzanne Zentko James O’Meara Ilie Barb Abby Foster Alice Boyette Yale Wang Desmond Jay Nedaa Skeik Robert S. Schwartz Rose Peterson Jo Anne Goldman Jessie Goldman

Importance Although early trials of endovascular renal denervation (RDN) for patients with resistant hypertension (RHTN) reported inconsistent results, ultrasound RDN (uRDN) was found to decrease blood pressure (BP) vs sham at 2 months in RHTN taking stable background medications the Study ReCor Medical Paradise System Clinical Hypertension (RADIANCE-HTN TRIO) trial. Objectives To report prespecified analysis persistence BP effects and safety uRDN 6 conjunction escalating antihypertensive...

10.1001/jamacardio.2022.3904 article EN cc-by-nc-nd JAMA Cardiology 2022-11-09

Objective The objective is to evaluate the 5-year follow-up results of percutaneous intramyocardial septal radiofrequency ablation (PIMSRA) for hypertrophic obstructive cardiomyopathy (HOCM), including clinical status, electrocardiographic and echocardiographic characteristics. Methods 27 patients (age: 44.3±15.5 years; 67% men, 33% women) with severely symptomatic HOCM who underwent PIMSRA from October 2016 September 2017 were included. Their resting exercise stress echocardiography,...

10.1136/heartjnl-2023-323606 article EN Heart 2024-02-22
Francisco Ujueta Gervasio A. Lamas Kevin J. Anstrom Ana Navas‐Acién Robin Boineau and 95 more Yves Rosenberg Mario Stylianou Teresa L.Z. Jones Bonnie R. Joubert Qilu Yu Jun Wen Hayley Nemeth Zhen Huang Vivian Fonseca David M. Nathan Gabriel I. Uwaifo Ivan A. Arenas Lan Luo Jeffrey Baker Diana Visentin André Paixão John F. Schmedtje Daniel B. Mark Philip Bear Donna Prouty Jodi Baxter Jonathan K. Ehrman Heather Golden Vikrant Katoch Raffi K. Krikorian André Paixão Fujiko Anazawa Leybi Ramirez-Kelly Abby Nolen Venus Barney Gerald Natzke Rodica Pop‐Busui Cindy Plunkett Laura Meyer J. Kirk Roberts Scott A. Rollins Tamra Hollis Nampalli Vijay Melinda Washam David Zidar Terence Semenec Lauren Huntington Amanda Klumpp Matthew S. Doughty Jeffrey Baker Joseph P. Allen Rebecca Cortez Bhaskar Purushottam Kirstin Stauffacher Kelly J. Airey Elena Christofides Jordyn Conway David Hoffman Patty Schuler Ronald M Solbrig Loni Chacon Phillip D. Levy Linda Gojcevic R. Eric Collins John Miles McClure Ellen Mook Christopher R. deFilippi Wendy Sheaffer Antoinette Bonaccorso Daniel Donovan Julee Hartwell Andrew P. Garner Dawn Kalbfliesh David H. Hsi Maryanne Ducey Paula Trump Urs A. Leuenberger Katie Loffredo Betty Persico Allan Magaziner Dennis Goodman Michela L. Garabedian J. Coates Jeanne P. Wingo Sheldon H. Gottlieb Michael Schächter Sally Minniefield Olakunle Akinboboye Kazi Masel Ullah Karen Wolske Dennis Friedman Daniel Lorber M. Tsovian Regina Druz Patricia Hodnett Stephanie Meller Maria B. Bartolome Giselle Cortez Vargas Ian Ergui Francisco Ujueta

Importance In 2013, the Trial to Assess Chelation Therapy (TACT) reported that in 1708 patients with stable coronary disease and prior myocardial infarction (MI), oral multivitamins multiminerals (OMVMs), a factorial design edetate disodium (EDTA) chelation therapy, did not reduce cardiovascular events relative placebo OMVMs, but active EDTA combined OMVMs was superior OMVM/placebo EDTA. Objective To compare OMVM vs terms of efficacy for reducing major adverse diabetes MI. Design, Setting,...

10.1001/jamainternmed.2024.8408 article EN cc-by JAMA Internal Medicine 2025-03-03

Background Patients with drug-refractory non-obstructive hypertrophic cardiomyopathy (NOHCM) lack effective invasive treatment options. This study aimed to evaluate the safety and effectiveness of percutaneous intramyocardial septal radiofrequency ablation (PIMSRA, Liwen procedure) in patients NOHCM severe hypertrophy (≥28 mm). Method single-arm, open-label, prospective enrolled 20 adult between June 2017 2023. underwent PIMSRA were followed for a median 15 months. Outcomes included changes...

10.1136/heartjnl-2024-325334 article EN cc-by Heart 2025-03-07
Gervasio A. Lamas Kevin J. Anstrom Ana Navas‐Acién Robin Boineau Hayley Nemeth and 95 more Zhen Huang Jun Wen Yves Rosenberg Mario Stylianou Teresa L.Z. Jones Bonnie R. Joubert Qilu Yu Regina M. Santella Ana C. Mon Francisco Ujueta Esteban Escolar David M. Nathan Vivian Fonseca Y. Wady Aude Jonathan K. Ehrman T.S.J. Elliott Rakesh Prashad Eldrin F. Lewis Renato D. Lopes Michael E. Farkouh Anne-Marie Elliott Jonathan Newman Daniel B. Mark Philip Bear Donna Prouty Jodi Baxter Jonathan K. Ehrman Heather Golden Vikrant Katoch Raffi K. Krikorian André Paixão Fujiko Anazawa Leybi Ramirez-Kelly Abby Nolen Venus Barney Gerald Natzke Rodica Pop‐Busui Cindy Plunkett Laura Meyer J. Kirk Roberts Scott A. Rollins Tamra Hollis Nampalli Vijay Melinda Washam David Zidar Terence Semenec Lauren Huntington Amanda Klumpp Matthew S. Doughty Jeffrey Baker Joseph P. Allen Rebecca Cortez Bhaskar Purushottam Kirstin Stauffacher Kelly J. Airey Elena Christofides Jordyn Conway David Hoffman Patty Schuler Ronald M Solbrig Loni Chacon Phillip D. Levy Linda Gojcevic R. Eric Collins John Miles McClure Ellen Mook Christopher R. deFilippi Wendy Sheaffer Antoinette Bonaccorso Daniel Donovan Julee Hartwell Andrew P. Garner Dawn Kalbfliesh David H. Hsi Maryanne Ducey Paula Trump Urs A. Leuenberger Katie Loffredo Betty Persico Allan Magaziner Dennis Goodman Michela L. Garabedian J. Coates Jeanne P. Wingo Sheldon H. Gottlieb Michael Schächter Sally Minniefield Olakunle Akinboboye Kazi Masel Ullah Karen Wolske Dennis Friedman Daniel Lorber M. Tsovian Regina Druz Patricia Hodnett

In 2013, the Trial to Assess Chelation Therapy (TACT) reported that edetate disodium (EDTA)-based chelation significantly reduced cardiovascular disease (CVD) events by 18% in 1708 patients with a prior myocardial infarction (MI).

10.1001/jama.2024.11463 article EN JAMA 2024-08-14

Abstract Background Light-chain (AL) amyloidosis is the most common type of systemic with poor prognosis. Currently, predictors cardiac involvement and prognostic staging systems are primarily based on conventional echocardiography serological biomarkers. We used three-dimensional speckle tracking (STE-3D) measurements strain, hypothesizing that it could detect aid in prediction mortality. Methods retrospectively analysed 74 consecutive patients biopsy-proven AL amyloidosis. Among them, 42...

10.1186/s12872-021-01856-3 article EN cc-by BMC Cardiovascular Disorders 2021-01-21

Broken heart syndrome, otherwise known as takotsubo is stress-induced cardiomyopathy. Clinical presentation mimics acute ST segment elevation myocardial infarction, but with characteristic left ventricular apical ballooning. The mechanism linked to overstimulation of the sympathetic system from high circulating catecholamine levels. We report a 46-year-old Caucasian female whose treatment status asthmaticus ketamine and epinephrine precipitated this syndrome. She required hemodynamic support...

10.1097/smj.0b013e31818f5bd8 article EN Southern Medical Journal 2009-03-01

Selecting an appropriate surgical approach for double-outlet right ventricle (DORV), a complex congenital cardiac malformation with many anatomic variations, is difficult. Therefore, we determined the feasibility of using echocardiographic classification system, which describes variations in more precise terms than current system does, to determine whether it could help direct plans. Our includes 8 DORV subtypes, categorized according 3 factors: relative positions great arteries (normal or...

10.14503/thij-16-5759 article EN Texas Heart Institute Journal 2017-08-01

Patients with cardiac tumors may present challenges for surgical resection due to poor clinical condition. Echocardiography-guided transapical radiofrequency ablation (TARFACT) potentially offers a less invasive palliative therapy option.

10.1016/j.jaccao.2024.03.008 article EN cc-by-nc-nd JACC CardioOncology 2024-04-30

Objective Echocardiography-guided Percutaneous IntraMyocardial Septal Radiofrequency Ablation (PIMSRA, Liwen procedure) is a novel treatment option for hypertrophic obstructive cardiomyopathy (HOCM). The impact of PIMSRA on myocardial mechanics unknown. Methods Between October 2016 and June 2019, 3-dimentional speckle tracking echocardiography were performed in 82 patients. Echocardiographic imaging, qualitative quantitative clinical assessment completed at baseline, immediately...

10.1136/heartjnl-2022-321597 article EN Heart 2022-10-21

Purpose As growing numbers of long‐term cancer survivors faced with the cardiac side effects by anthracycline treatment, it is necessary to explore optimal monitoring method for early detection toxicity. Methods We conducted a retrospective analysis 82 consecutive patients diffuse large B‐cell lymphoma treated chemotherapy. Echocardiographic Doppler imaging‐derived Tei index and mitral annular peak systolic velocity (Sm) measured tissue imaging TDI , serum high‐sensitivity troponin T (hs‐...

10.1111/echo.13704 article EN Echocardiography 2017-09-24

Left atrial (LA) function and mechanical dispersion changes in breast cancer patients treated with chemotherapy remain unclear.LA LA would be impaired after chemotherapy.This single-center retrospective study included 91 consecutive 30 controls. Patients were examined by echocardiography three times at intervals. Conventional parameters, left ventricular strain, evaluated compared.LA strain during reservoir phase (LASr), conduit (LAScd), contraction (LASct) all decreased markedly lower than...

10.1002/clc.23813 article EN Clinical Cardiology 2022-03-16
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