David H. Hsi
- Cardiac Imaging and Diagnostics
- Cardiovascular Function and Risk Factors
- Cardiomyopathy and Myosin Studies
- Cardiac Arrhythmias and Treatments
- Cardiac Structural Anomalies and Repair
- Cardiovascular Effects of Exercise
- Infective Endocarditis Diagnosis and Management
- Cardiac Valve Diseases and Treatments
- Cardiac tumors and thrombi
- Blood Pressure and Hypertension Studies
- Atrial Fibrillation Management and Outcomes
- Pericarditis and Cardiac Tamponade
- Congenital Heart Disease Studies
- Chemotherapy-induced cardiotoxicity and mitigation
- Cardiac pacing and defibrillation studies
- Cardiovascular Disease and Adiposity
- Cardiac electrophysiology and arrhythmias
- Hemodynamic Monitoring and Therapy
- Coronary Artery Anomalies
- Pulmonary Hypertension Research and Treatments
- Kawasaki Disease and Coronary Complications
- Aortic Disease and Treatment Approaches
- Coronary Interventions and Diagnostics
- Renal and Vascular Pathologies
- Acute Myocardial Infarction Research
Stamford Hospital
2016-2024
Columbia University
2017-2024
Bridgeport Hospital
2024
Yale New Haven Hospital
2024
Radiance Technologies (United States)
2022-2023
Royal College of Physicians
2018
Chinese Academy of Medical Sciences & Peking Union Medical College
2017
Fu Wai Hospital
2017
Deborah Heart and Lung Center
2013-2014
Robert Wood Johnson University Hospital
2014
Patients with hypertrophic obstructive cardiomyopathy (HOCM) and drug-refractory symptoms outflow gradients have limited nonsurgical treatment options. The feasibility of percutaneous intramyocardial septal radiofrequency ablation (PIMSRA) has been reported previously; however, procedural medium-term outcomes are unknown.To describe the safety PIMSRA in a large patient cohort HOCM.This was single-arm, open-label study patients HOCM. presenting to Xijing Hospital Xi'an, China, between October...
The purpose of this study was to assess the associations between 3-dimensional echocardiography (3DE)-derived changes in right ventricular (RV) volumes and strains with subsequent RV cardiotoxicity patients treated anthracyclines.Although early detection prediction left (LV) dysfunction has been widely studied receiving anthracyclines, little is known about size function population.A total 74 diffuse large B-cell lymphoma who received 6 cycles anthracycline-based treatment were enrolled....
Background: Immune checkpoint inhibitor (ICI)-associated myocarditis is an uncommon and potentially fatal immune-related adverse event (irAE). Although corticosteroids are recommended as the first-line treatment by current guidelines, patients still have variable responses to it, guidelines vary significantly in terms of strategies. Objectives: In this study, we performed a retrospective analysis ICI-associated our hospital propose new comparative aid individualized treatment. Methods: We...
Importance Although early trials of endovascular renal denervation (RDN) for patients with resistant hypertension (RHTN) reported inconsistent results, ultrasound RDN (uRDN) was found to decrease blood pressure (BP) vs sham at 2 months in RHTN taking stable background medications the Study ReCor Medical Paradise System Clinical Hypertension (RADIANCE-HTN TRIO) trial. Objectives To report prespecified analysis persistence BP effects and safety uRDN 6 conjunction escalating antihypertensive...
Objective The objective is to evaluate the 5-year follow-up results of percutaneous intramyocardial septal radiofrequency ablation (PIMSRA) for hypertrophic obstructive cardiomyopathy (HOCM), including clinical status, electrocardiographic and echocardiographic characteristics. Methods 27 patients (age: 44.3±15.5 years; 67% men, 33% women) with severely symptomatic HOCM who underwent PIMSRA from October 2016 September 2017 were included. Their resting exercise stress echocardiography,...
Importance In 2013, the Trial to Assess Chelation Therapy (TACT) reported that in 1708 patients with stable coronary disease and prior myocardial infarction (MI), oral multivitamins multiminerals (OMVMs), a factorial design edetate disodium (EDTA) chelation therapy, did not reduce cardiovascular events relative placebo OMVMs, but active EDTA combined OMVMs was superior OMVM/placebo EDTA. Objective To compare OMVM vs terms of efficacy for reducing major adverse diabetes MI. Design, Setting,...
Background Patients with drug-refractory non-obstructive hypertrophic cardiomyopathy (NOHCM) lack effective invasive treatment options. This study aimed to evaluate the safety and effectiveness of percutaneous intramyocardial septal radiofrequency ablation (PIMSRA, Liwen procedure) in patients NOHCM severe hypertrophy (≥28 mm). Method single-arm, open-label, prospective enrolled 20 adult between June 2017 2023. underwent PIMSRA were followed for a median 15 months. Outcomes included changes...
In 2013, the Trial to Assess Chelation Therapy (TACT) reported that edetate disodium (EDTA)-based chelation significantly reduced cardiovascular disease (CVD) events by 18% in 1708 patients with a prior myocardial infarction (MI).
Abstract Background Light-chain (AL) amyloidosis is the most common type of systemic with poor prognosis. Currently, predictors cardiac involvement and prognostic staging systems are primarily based on conventional echocardiography serological biomarkers. We used three-dimensional speckle tracking (STE-3D) measurements strain, hypothesizing that it could detect aid in prediction mortality. Methods retrospectively analysed 74 consecutive patients biopsy-proven AL amyloidosis. Among them, 42...
Broken heart syndrome, otherwise known as takotsubo is stress-induced cardiomyopathy. Clinical presentation mimics acute ST segment elevation myocardial infarction, but with characteristic left ventricular apical ballooning. The mechanism linked to overstimulation of the sympathetic system from high circulating catecholamine levels. We report a 46-year-old Caucasian female whose treatment status asthmaticus ketamine and epinephrine precipitated this syndrome. She required hemodynamic support...
Selecting an appropriate surgical approach for double-outlet right ventricle (DORV), a complex congenital cardiac malformation with many anatomic variations, is difficult. Therefore, we determined the feasibility of using echocardiographic classification system, which describes variations in more precise terms than current system does, to determine whether it could help direct plans. Our includes 8 DORV subtypes, categorized according 3 factors: relative positions great arteries (normal or...
Patients with cardiac tumors may present challenges for surgical resection due to poor clinical condition. Echocardiography-guided transapical radiofrequency ablation (TARFACT) potentially offers a less invasive palliative therapy option.
Objective Echocardiography-guided Percutaneous IntraMyocardial Septal Radiofrequency Ablation (PIMSRA, Liwen procedure) is a novel treatment option for hypertrophic obstructive cardiomyopathy (HOCM). The impact of PIMSRA on myocardial mechanics unknown. Methods Between October 2016 and June 2019, 3-dimentional speckle tracking echocardiography were performed in 82 patients. Echocardiographic imaging, qualitative quantitative clinical assessment completed at baseline, immediately...
Purpose As growing numbers of long‐term cancer survivors faced with the cardiac side effects by anthracycline treatment, it is necessary to explore optimal monitoring method for early detection toxicity. Methods We conducted a retrospective analysis 82 consecutive patients diffuse large B‐cell lymphoma treated chemotherapy. Echocardiographic Doppler imaging‐derived Tei index and mitral annular peak systolic velocity (Sm) measured tissue imaging TDI , serum high‐sensitivity troponin T (hs‐...
Left atrial (LA) function and mechanical dispersion changes in breast cancer patients treated with chemotherapy remain unclear.LA LA would be impaired after chemotherapy.This single-center retrospective study included 91 consecutive 30 controls. Patients were examined by echocardiography three times at intervals. Conventional parameters, left ventricular strain, evaluated compared.LA strain during reservoir phase (LASr), conduit (LAScd), contraction (LASct) all decreased markedly lower than...