A5024489469- Peripheral Artery Disease Management
- Heavy Metal Exposure and Toxicity
- Trace Elements in Health
- Cerebrovascular and Carotid Artery Diseases
- Vascular Procedures and Complications
- Diabetic Foot Ulcer Assessment and Management
- Climate Change and Health Impacts
- Air Quality and Health Impacts
- Cardiovascular Function and Risk Factors
- Cardiac electrophysiology and arrhythmias
- Central Venous Catheters and Hemodialysis
- Heavy metals in environment
- Effects and risks of endocrine disrupting chemicals
- Cardiac Arrhythmias and Treatments
- Cardiac Imaging and Diagnostics
- Venous Thromboembolism Diagnosis and Management
- Muscle and Compartmental Disorders
- Cardiovascular Disease and Adiposity
- Infective Endocarditis Diagnosis and Management
- Renal and Vascular Pathologies
- Acute Myocardial Infarction Research
- Anatomy and Medical Technology
- Vascular anomalies and interventions
- Diagnosis and Treatment of Venous Diseases
- Acute Ischemic Stroke Management
Brigham and Women's Hospital
2025
Mount Sinai Medical Center
2018-2024
Columbia University
2020-2023
Jackson Memorial Hospital
2023
University of Miami
2023
Mount Sinai Hospital
2022
NYU Langone Health
2017
Exposure to environmental pollutants is linked increased risk of cardiovascular disease. Beyond the extensive evidence for particulate air pollution, accumulating supports that exposure nonessential metals such as lead, cadmium, and arsenic a significant contributor disease worldwide. Humans are exposed through air, water, soil, food industrial public use. Contaminant interfere with critical intracellular reactions functions leading oxidative stress chronic inflammation result in endothelial...
In 2013, the Trial to Assess Chelation Therapy (TACT) reported that edetate disodium (EDTA)-based chelation significantly reduced cardiovascular disease (CVD) events by 18% in 1708 patients with a prior myocardial infarction (MI).
Importance In 2013, the Trial to Assess Chelation Therapy (TACT) reported that in 1708 patients with stable coronary disease and prior myocardial infarction (MI), oral multivitamins multiminerals (OMVMs), a factorial design edetate disodium (EDTA) chelation therapy, did not reduce cardiovascular events relative placebo OMVMs, but active EDTA combined OMVMs was superior OMVM/placebo EDTA. Objective To compare OMVM vs terms of efficacy for reducing major adverse diabetes MI. Design, Setting,...
Approximately 1 in 7 US adults have diabetes; and over 60% of deaths patients with diabetes cardiac disease as a principal or contributing cause. Both coronary peripheral artery (PAD) identify high-risk cohorts among diabetes. We previously demonstrated improved cardiovascular outcomes edetate disodium-based chelation post-MI diabetes, enrolled the Trial to Assess Chelation Therapy (TACT). In these analyses we further studied effect size severe 2 vascular beds; coronaries, lower extremity...
Background In 2015, there were 30.3 million patients with diabetes in the US, including 25.2% of people ages 65 or older and 108,000 hospitalizations for non-traumatic amputations. Severe diabetic limb disease includes critical ischemia (CLI ) due to an infrapopliteal foot pain ischemic ulcerations gangrene. Environmentally acquired toxic metals, such as lead cadmium, have been associated cardiovascular disease. Thus, we designed present unblinded pilot study determine whether was a signal...
Peripheral artery disease (PAD) is a progressive form of atherosclerosis that affects the lower extremities, particularly in patients with diabetes. Critical limb ischemia (CLI), end-stage manifestation this disease, associated an increased risk chronic leg ulcerations, infections, amputations, and mortality. At presentation, 30% CLI require amputation, 25% will die within 1 year (1). Toxic metal exposure, to cadmium, has been vascular epidemiological studies PAD severity coronary (CAD)...