A5101526529- Electrolyte and hormonal disorders
- Potassium and Related Disorders
- Acute Kidney Injury Research
- Venous Thromboembolism Diagnosis and Management
- Atrial Fibrillation Management and Outcomes
- Cardiac Arrest and Resuscitation
- Aortic Disease and Treatment Approaches
- Systemic Lupus Erythematosus Research
- Aortic aneurysm repair treatments
- Liver Disease and Transplantation
- Radiopharmaceutical Chemistry and Applications
- Cerebral Venous Sinus Thrombosis
- Infectious Aortic and Vascular Conditions
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Pancreatitis Pathology and Treatment
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Pharmacological Effects and Toxicity Studies
- Systemic Sclerosis and Related Diseases
- Vasculitis and related conditions
- Mechanical Circulatory Support Devices
- Dialysis and Renal Disease Management
- Medical Imaging and Pathology Studies
- Biomedical and Chemical Research
- Muscle and Compartmental Disorders
- Sarcoidosis and Beryllium Toxicity Research
Air Force Medical University
2013-2025
Xijing Hospital
2013-2025
China Medical University
1999-2010
China Medical University Hospital
1999-2010
The shortage of donors is a major challenge for transplantation; however, organs from genetically modified pigs can serve as ideal supplements1,2. Until now, porcine hearts and kidneys have been successively transplanted into humans3–7. In this study, heterotopic auxiliary transplantation was used to donate six-gene-edited pig liver brain-dead recipient. graft function, haemodynamics, immune inflammatory responses the recipient were monitored over subsequent 10 days. Two hours after portal...
Abstract Background Light-chain (AL) amyloidosis is the most common type of systemic with poor prognosis. Currently, predictors cardiac involvement and prognostic staging systems are primarily based on conventional echocardiography serological biomarkers. We used three-dimensional speckle tracking (STE-3D) measurements strain, hypothesizing that it could detect aid in prediction mortality. Methods retrospectively analysed 74 consecutive patients biopsy-proven AL amyloidosis. Among them, 42...
The evidence for high-volume hemofiltration plus hemoperfusion (HVHF&HP) hyperlipidemic severe acute pancreatitis (HL-SAP) is anecdotal. purpose of our study was to evaluate the efficacy HVHF&HP HL-SAP in a prospective controlled study.Prospective pilot between May 2010 and 2013 hospital intensive care unit.HL-SAP patients chose conventional treatment alone (the control group) or combined with experimental protocol were prospectively followed hospital. APACHE II score, SOFA ICU stay...
Background The opinions on the efficacy and safety of no anticoagulation versus regional citrate for continuous KRT (CKRT) were controversial in patients with severe liver failure a higher bleeding risk. We performed randomized controlled trial to assess CKRT these patients. Methods Adult risk who required considered candidates. included participants receive or no-anticoagulation CKRT. primary end point was filter failure. Results Of participants, 44 45 CKRT, respectively. group had...
The use of human albumin in patients with minimal change disease (MCD) remains controversial. aim the current study was to assess whether infusion increased risk acute kidney injury (AKI) adult MCD.
Abstract Background Hyperbilirubinemia is one of the common complications after cardiac surgery and associated with increased mortality. However, to best our knowledge, reports on clinical significance postoperative severe hyperbilirubinemia in Stanford type A aortic dissection (AAD) patients were limited. Methods Patients who underwent surgical treatment for AAD center between January 2015 December 2018 retrospectively screened. In-hospital mortality, long-term acute kidney injury (AKI),...
Technetium-99m ethyl cysteinate dimer (Tc-99m ECD) brain single photon emission computed tomography (SPECT) has been used to detect abnormal regional cerebral blood flow (rCBF) in women with primary fibromyalgia (FM). The main aim of this study was investigate the rCBF deficit concomitant FM patients and compare it FM.An observational designed analyse SPECT findings 92 female recruited from January 2002 2004. Differences hypoperfusive areas between 49 29 were assessed different using...
Patients with severe hypernatremia who receive conventional treatment are often undertreated. Data on the management of acute using continuous venovenous hemofiltration (CVVH) limited to anecdotes. This study aimed evaluate efficacy and safety CVVH for in critically ill patients a retrospective cohort. A total 95 were admitted our ICU between January 2009 2014 analyzed as original These divided into groups. The groups then matched by age, reason admission, vasopressor dependency, basic serum...
Purpose We conducted a retrospective study to evaluate the efficacy and safety of regional citrate anticoagulation (RCA) versus those low molecular weight heparin (LMWH) for CVVH in severe hypercalcemia patients.Methods Between January 2014 May 2019, 33 patients underwent CVVH. Patients were divided into RCA LMWH groups. Calcium-free replacement solution was used. Serum total calcium reduction rate (RRSeCa), filter lifespan, bleeding, totCa/ionCa ratio, accumulation, catheter occlusion...
Abstract Background Hyperbilirubinemia after heart valve surgery (HVS) with cardiopulmonary bypass is frequently observed and associated worse outcomes. We investigated the characteristics prognosis of patients severe hyperbilirubinemia HVS for rheumatic disease (RHD) to identify clinical outcomes potential risk factors. Methods Between 2015 2018, who underwent in cardiac intensive care unit our hospital were retrospectively screened. Risk factors acute kidney injury (AKI), requirement...
Continuous venovenous hemofiltration (CVVH) is an important organ supportive technique. This study aimed to evaluate the impact of early classic CVVH on outcomes severe acute pancreatitis (SAP) patients with failure (EOF). Between 2008 and 2012, a total 44 SAP EOF were admitted our department. The classified into two groups according whether they received (2 L/h, initiated within 24 h after admission): 25 (ECVVH group), 19 did not receive (control group). matched for age Acute Physiology...
Coronavirus disease 2019 (COVID-19) spread worldwide and presented a significant threat to people's health. Inappropriate assessment treatment strategies bring heavy burden on healthcare systems. Our study aimed construct predictive models assess patients with COVID-19 who may have poor prognoses early accurately. This research performed retrospective analysis two cohorts of COVID-19. Data from the Barcelona cohort were used as training set, data Rotterdam validation set. Cox regression,...
The current treatments of toxic epidermal necrolysis (TEN) are limited to the discontinuation a suspect medication and supportive measures. We conducted retrospective study evaluate efficacy adding continuous venovenous hemofiltration (CVVH) hemoperfusion (HP) conventional treatment for TEN.TEN patients who were admitted our center between January 2008 May 2016 considered as candidates. included divided into CVVH&HP group (n = 34) according their accepted therapies during hospital stay.The...
Background Heparin anticoagulation (HA) is commonly employed for membrane therapeutic plasma exchange (mTPE). However, patients with increased bleeding risk, there were controversial opinions on the use of HA versus regional citrate (RCA) mTPE. Our present study aimed to evaluate efficacy and safety vs. RCA mTPE in risk.Methods Patients risk who underwent between 2014 2021 our center screened. Observations used as endpoints.Results A total 108 368 sessions included. Of included patients, 38...