Objective Emergency patients with hypoalbuminemia are known to have increased mortality. No previous studies have, however, assessed the predictive value of low albumin on mortality in unselected acutely admitted medical patients. We aimed at assessing power 30-day all-cause a cohort Methods included all adult from admission unit regional teaching hospital Denmark. Data was extracted Danish Civil Register ensure complete follow-up. Patients were divided into three groups according their...

While Denmark is well known for its plethora of registers. Many studies are conducted on research databases that only cover parts Denmark, and regional differences could potentially threaten these studies' external validity. The aim this study was to assess sociodemographic health related homogeneity the five Danish regions.We obtained descriptive data regions, using publicly available sources: Statbank Ministry Economic Affairs, Medstat.dk. These sources comprise aggregate from four...

Objective: Sepsis is a frequent cause of admission, but incidence rates based on administrative data have previously produced large differences in estimates. The aim the study was to estimate community-acquired sepsis patients’ symptoms and clinical findings at arrival hospital. Design: Population-based survey. Setting: Medical emergency department from September 1, 2010, August 31, 2011. Patients: All patients were manually reviewed using structured protocol order identify presence...

Long-term oral corticosteroid (OCS) treatment for severe asthma is known to cause significant adverse effects, but knowledge on effects of lower exposures in general populations limited. We aimed explore this a nationwide Danish population.Users medication aged 18-45 years were identified the registers during 1999-2018 and followed prospectively an open-cohort design. Incident OCS users matched 1:4 nonusers by propensity scores with replacement. Associations between use incident...

Objective Patients that initially appear stable on arrival to the hospital often have less intensive monitoring of their vital signs, possibly leading excess mortality. The aim was describe risk factors for deterioration in signs and related prognosis among patients with normal at a medical emergency department (MED). Design setting Single-centre, retrospective cohort study all admitted MED from September 2010-August 2011. Subjects were included when (systolic blood pressure, pulse rate,...

Metformin constitutes first-line treatment of type 2 diabetes mellitus. It is presumed to have lactic acidosis as a dangerous, but rare, side effect.

Background There may be distinctly different ways for general practices to serve the growing population of older patients, providing them combinations face-to-face-, telephone-, and e-mail consultations, home visits, chronic care reviews. Aim To identify latent practice profiles frequency combination consultation types patients relate characteristics. Design & setting Register-based cohort study all Danish citizens aged≥75 years. Method For each years 2017-2021, a profile analysis was...

In 1965, Doreen Henriksen began her lymphedema journey, diagnosed with toxemia during pregnancy, leading to chronic swelling. It took 49 years for an official diagnosis from Dr. Rajender Hanmiah, who recommended management steps including moisturization, lymphatic drainage, and compression stockings. Doreen's daily routine is extensive, involving exercises, a circulation machine, assistance husband. She advocates awareness better care, emphasizing the need comprehensive support those...

Background: Hospital readmissions are increasingly used as a quality indicator with belief that they marker of poor care and have led to financial penalties in UK USA. Risk scoring systems, such LACE HOSPITAL, been proposed tools for identifying patients at high risk readmission but not validated international populations. Aim: To perform an external independent validation the HOSPITAL scores. Design: An unplanned secondary cohort study. Methods: Patients admitted medical admission unit...

Background Credible measures of disease incidence, trends and mortality can be obtained through surveillance using manual chart review, but this is both time-consuming expensive. ICD-10 discharge diagnoses are used as surrogate markers infection, knowledge on the validity infections in general sparse. The aim study was to determine how well identify patients with community-acquired a medical emergency department (ED), overall related sites infection patient characteristics. Methods We...

The knowledge of the etiology and associated mortality undifferentiated shock in emergency department (ED) is limited. We aimed to describe etiology-based proportions incidence rates (IR) shock, as well ED.Population-based cohort study at a University Hospital ED Denmark from January 1, 2000, December 31, 2011. Patients aged ≥18 years living ED-catchment area (N = 225,000) with first-time presentation (n 1,553) defined hypotension (systolic blood pressure ≤100 mm Hg) ≥1 organ failures were...

Objectives To describe changes in unplanned acute activity and to identify characterise contacts hospitals Denmark from 2005 2016, including following healthcare reform. Design Descriptive study. Setting Data Danish nationwide registers. Population Adults (≥18 years). Participants All adults with an hospital (acute inpatient admissions emergency care visits) 2016. Primary secondary outcome measures Outcomes were annual number of contacts, length stay, per 1000 citizen year, age-adjusted...

Sodium-glucose cotransporter-2 inhibitors (SGLT2-I) are frequently used in type 2 diabetes and have recently been associated with lower rates of gout compared to glucagon-like peptide-1 receptor agonists (GLP1-RA). Our objective was assess the association between SGLT2-I initiation using a cohort study design symmetry analysis.Using Danish nationwide health registries, we conducted an active comparator, new user comparing 3-year risk among users propensity score matched GLP1-RA users....

In patients with impaired renal function, drug dose adjustment is often required. Non-adherence to clinical prescribing recommendations may result in severe adverse events. previous studies, the prevalence rate of non-adherence recommended dosing has been reported be 19-67%. Using support system Renbase(®) as reference, we investigated use and drugs function a university hospital setting using electronic prescription automatic reporting estimated glomerular filtration (eGFR). all, 232 an...

Background The aim of the study was to estimate risk factors for hospitalization due sepsis and determine whether these vary by age gender. Methods We performed a population-based case-control all adult patients admitted medical ED from September 2010 August 2011. Controls were sampled within hospital catchment-area. All potential cases manually validated using structured protocol. Vital signs laboratory values measured at arrival registered define systemic inflammatory response syndrome...