Faisal Sharif
- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Blood Pressure and Hypertension Studies
- Cardiac Valve Diseases and Treatments
- Acute Myocardial Infarction Research
- Cerebrovascular and Carotid Artery Diseases
- Cardiovascular Health and Disease Prevention
- Peripheral Artery Disease Management
- Heart Rate Variability and Autonomic Control
- Hemodynamic Monitoring and Therapy
- Cardiovascular Syncope and Autonomic Disorders
- Sodium Intake and Health
- Aortic aneurysm repair treatments
- Antiplatelet Therapy and Cardiovascular Diseases
- Renal and Vascular Pathologies
- Infective Endocarditis Diagnosis and Management
- Cardiovascular Function and Risk Factors
- Heart Failure Treatment and Management
- Cardiac, Anesthesia and Surgical Outcomes
- Lipoproteins and Cardiovascular Health
- Pulmonary Hypertension Research and Treatments
- Mechanical Circulatory Support Devices
- Migraine and Headache Studies
- Cardiac Arrhythmias and Treatments
- Cardiac pacing and defibrillation studies
Ollscoil na Gaillimhe – University of Galway
2016-2025
University Hospital Galway
2015-2025
Saolta University Health Care Group
2020-2025
Health Service Executive
2021-2024
Medtronic (United States)
2024
Radiance Technologies (United States)
2023
National University of Ireland
2004-2021
University of Amsterdam
2021
Amsterdam University Medical Centers
2021
HITEC University
2020
Renal denervation (RDN) reduces blood pressure (BP) in patients with uncontrolled hypertension the absence of antihypertensive medications.
Coronary computed tomographic angiography (CCTA) is becoming the first-line investigation for establishing presence of coronary artery disease and, with fractional flow reserve (FFRCT), its haemodynamic significance. In patients without significant epicardial obstruction, role either to rule out atherosclerosis or detect subclinical plaque that should be monitored progression/regression following prevention therapy and provide risk classification. Ischaemic non-obstructive arteries are also...
BACKGROUND: The SPYRAL HTN-ON MED (Global Clinical Study of Renal Denervation With the Symplicity Spyral Multi-electrode System in Patients Uncontrolled Hypertension Absence Antihypertensive Medications)trial showed significant office and nighttime systolic blood pressure (BP) reductions patients with hypertension following renal denervation (RDN) compared sham-control patients, despite similar 24-hour BP reductions. We antihypertensive medication changes among prespecified subpopulations....
Abstract
Incorporation of remote monitoring pulmonary artery pressure and vital signs has been demonstrated to reduce heart failure (HF) hospitalization all-cause mortality in selected symptomatic HF patients. The aim this study is investigate the safety accuracy new CordellaTM Pulmonary Artery Pressure Sensor (Endotronix, Inc., Chicago, IL, USA) usability comprehensive Heart Failure System (CHFS).Multicentre, open-label, first-in-human, feasibility evaluate CHFS Cordella™ 15 patients with New York...
Renal denervation (RDN) has been shown to lower blood pressure (BP), but its effects on cardiovascular events have only preliminarily evaluated. Time in therapeutic range (TTR) of BP is associated with events. This study sought assess the impact catheter-based RDN TTR and association outcomes GSR (Global SYMPLICITY Registry). Patients uncontrolled hypertension were enrolled treated radiofrequency RDN. Office ambulatory systolic (OSBP ASBP) measured at 3, 6, 12, 24, 36 months postprocedure...
Ten-year all-cause death according to incomplete (IR) versus complete revascularization (CR) has not been fully investigated in patients with 3-vessel disease and left main coronary artery undergoing percutaneous intervention (PCI) bypass grafting (CABG).The SYNTAX Extended Survival study (Synergy Between PCI With TAXUS Cardiac Surgery: [SYNTAXES]) evaluated vital status up 10 years who were originally enrolled the trial. In present substudy, outcomes of CABG CR group compared IR, CR, IR...
Ultrasound and radiofrequency renal denervation (RDN) have been shown to safely lower blood pressure (BP) in hypertension.
Abstract Aims In the SIRONA 2 trial, safety and efficacy of pulmonary artery (PA) pressure (PAP)‐guided heart failure (HF) management using a novel PAP sensor were assessed at 30 90 days, respectively, both endpoints met. The current study examines prespecified secondary accuracy PA along with HF hospitalizations mortality, symptoms, functional capacity, quality life, patient compliance through 12 months. Methods results is prospective, multi‐centre, open‐label, single‐arm trial evaluating...
Abstract Aims Implantable pulmonary artery pressure (PAP) sensors have been shown to reduce heart failure hospitalizations (HFH) in selected patients. The goal of this study was evaluate the safety and efficacy a novel wireless PAP monitoring system patients with (HF). Methods results This is prospective, multi‐centre, open‐label, single‐arm trial evaluating Cordella™ PA Sensor System including comprehensive Heart Failure (CHFS) New York Association (NYHA) Class III hospitalization and/or...
The Global SYMPLICITY Registry DEFINE (Denervation Findings in Real World) investigates radiofrequency renal denervation (RDN) a broad range of patients with hypertension. We evaluated whether the number or type antihypertensive medications were associated increased long-term blood pressure (BP) reductions and cardiovascular outcomes following RDN.Patients underwent RDN categorized by baseline (0-3 ≥4) different combinations medication classes. BP changes compared between groups through 36...
Monitoring supine pulmonary artery pressures to guide heart failure (HF) management has reduced HF hospitalizations in select patients. The purpose of this study was evaluate the effect managing seated mean pressure (mPAP) with Cordella Pulmonary Artery sensor on outcomes patients HF. Following GUIDE-HF (Hemodynamic-GUIDEd Management Heart Failure Trial), U.S. Food and Drug Administration input, PROACTIVE-HF (A Prospective, Multi-Center, Open Label, Single Arm Clinical Trial Evaluating...
Heart failure (HF) is a multi-faceted, complex clinical syndrome characterized by significant morbidity, high mortality rate, reduced quality of life, and rapidly increasing healthcare costs. A larger proportion these costs comprise both ambulatory emergency department visits, as well hospital admissions. Despite the methods used telehealth (TH) to improve self-care patient outcomes remain poor. HF management associated with numerous challenges, such conflicting evidence from trials,...