- Coronary Interventions and Diagnostics
- Peripheral Artery Disease Management
- Cardiac Imaging and Diagnostics
- Cerebrovascular and Carotid Artery Diseases
- Vascular Procedures and Complications
- Acute Myocardial Infarction Research
- Blood Pressure and Hypertension Studies
- Antiplatelet Therapy and Cardiovascular Diseases
- Aortic aneurysm repair treatments
- Aortic Disease and Treatment Approaches
- Cardiac Valve Diseases and Treatments
- Cardiac Arrhythmias and Treatments
- Heart Rate Variability and Autonomic Control
- Renal and Vascular Pathologies
- Hemodynamic Monitoring and Therapy
- Axon Guidance and Neuronal Signaling
- Biochemical effects in animals
- Cardiovascular Health and Disease Prevention
- Intracranial Aneurysms: Treatment and Complications
- Cardiac, Anesthesia and Surgical Outcomes
- Central Venous Catheters and Hemodialysis
- Wnt/β-catenin signaling in development and cancer
- Hippo pathway signaling and YAP/TAZ
- Cardiac Structural Anomalies and Repair
- Aortic Thrombus and Embolism
Clinique Pasteur
2014-2024
Radiance Technologies (United States)
2022-2023
Sigmund Freud University Vienna
2022-2023
Wilhelminen Hospital
2022-2023
Society of Interventional Radiology
2022
October 6 University
2022
Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda
2022
Inserm
2009-2014
Hôpital Rangueil
2010-2014
Institut des Maladies Métaboliques et Cardiovasculaires
2012-2014
Renal denervation (RDN) reduces blood pressure (BP) in patients with uncontrolled hypertension the absence of antihypertensive medications.
Coronary intravascular lithotripsy (IVL) safely facilitates successful stent implantation in severely calcified lesions. This analysis sought to determine the relative impact of lesion calcium eccentricity on safety and effectiveness IVL using high-resolution optical coherence tomography imaging.Individual patient-level data (n=262) were pooled from 4 distinct international prospective studies (Disrupt CAD I, II, III, IV) analyzed by an independent core laboratory. performance eccentric...
Circumferential ablation of renal sympathetic nerves using catheter-based ultrasound energy was studied in a preclinical vivo model. The aim to investigate the benefit cooling arterial wall and extent nerve injury based on histopathology, correlate with kidney norepinephrine levels.Computer simulations transducer within balloon demonstrated circumferentially uniform heating profile. In characterisation performed 10 normotensive pigs. Nine were treated bilaterally survived for seven days...
Bortezomib is a proteasome inhibitor commonly indicated for the treatment of multiple myeloma and non Hodgkin lymphoma. Cardiac adverse drug reactions this are not clearly established. We report case where direct involvement bortezomib in occurrence heart failure strongly suspected 22 other cases spontaneously reported to French Pharmacovigilance System. This should increase cardiologist awareness about risk related drug. Moreover, these underline need systematic cardiac screening patients...
BACKGROUND: Limited information is available on the comparative efficacy and safety of different stent platforms in patients at high bleeding risk undergoing an abbreviated dual antiplatelet therapy duration after percutaneous coronary intervention (PCI). The aim this study was to compare effectiveness biodegradable-polymer sirolimus-eluting with durable-polymer zotarolimus-eluting receiving 1 month PCI. METHODS: Bioflow-DAPT Study international, randomized, open-label trial conducted 52...
Heavily calcified peripheral artery lesions increase the risk of vascular complications, constituting a severe challenge for operator during catheter-based cardiovascular interventions. Intravascular Lithotripsy (IVL) technology disrupts subendothelial calcification by using localized pulsative sonic pressure waves and represents promising technique plaque modification in patients with arteries.
Despite improvement in devices, in-stent restenosis remains a frequent and challenging complication of percutaneous coronary interventions.
Cardiac tissue cohesion relying on highly ordered cardiomyocytes (CM) interactions is critical because most cardiomyopathies are associated with remodeling and architecture alterations.Eph/ephrin system constitutes a ubiquitous coordinating cellular communications which recently emerged as major regulator in adult organs. We examined if eph/ephrin could participate cardiac cyto-organization.We reported the expression of ephrin-B1 both endothelial cells for first time CMs where localized...
The aim of this study was to assess the safety and effectiveness intravascular lithotripsy (IVL) in treating eccentric calcified coronary lesions.Between December 2015 March 2019, 180 patients were enrolled Disrupt CAD I II studies across 19 sites 10 countries. Patient-level data pooled from these two (n = 180), within which 47 lesions (26%) 133 concentric identified.Clinical success, defined as residual stenosis < 50% after stenting no in-hospital MACE, similar between cohorts (93.6% vs....
The aim of the study was to assess 24-month efficacy and safety a novel drug-eluting stent (DES) for femoropopliteal interventions with an innovative design abluminal reservoir technology releasing amphilimus formulation (sirolimus plus fatty acid) efficient drug transfer optimized release kinetics. DES paclitaxel exhibited good patency rates after interventions. No benefit has been reported when sirolimus or everolimus were used antiproliferative coating. Within multicenter, first-in-man,...
We describe the first use of transradial access renal denervation in a patient with resistant hypertension using dedicated radiofrequency catheter (Iberis™; Terumo Medical Corporation, Tokyo, Japan). The system includes generator and 4 Fr single-use (RF) device which has to be introduced via 6 guiding catheter. Radiofrequency energy is delivered at tip was CE approved March 2013.
Background while the duration of dual antiplatelet therapy (DAPT) following coronary angioplasty for chronic syndrome (CCS) recommended by European Society Cardiology has decreased over last decade, little is known about adherence to those guidelines in clinical practice France. Aim To analyze real DAPT post CCS, as well factors affecting this duration. Methods Between 2014 and 2019, 8.836 percutaneous interventions CCS from France-PCI registry were evaluated, with 1 year follow up, after...
Coronary intravascular lithotripsy (IVL) safely facilitates stent implantation in severely calcified lesions.