- Cardiac Imaging and Diagnostics
- Cardiac Valve Diseases and Treatments
- Coronary Interventions and Diagnostics
- Advanced MRI Techniques and Applications
- Cardiovascular Function and Risk Factors
- Infective Endocarditis Diagnosis and Management
- Acute Myocardial Infarction Research
- Ultrasound and Hyperthermia Applications
- Cardiovascular Disease and Adiposity
- Peripheral Artery Disease Management
- Antiplatelet Therapy and Cardiovascular Diseases
- Aortic Disease and Treatment Approaches
- Viral Infections and Immunology Research
- Atrial Fibrillation Management and Outcomes
- Cardiac pacing and defibrillation studies
- Vascular Procedures and Complications
- Cardiomyopathy and Myosin Studies
- Cardiac Arrhythmias and Treatments
- Cerebrovascular and Carotid Artery Diseases
- Advanced X-ray and CT Imaging
- Venous Thromboembolism Diagnosis and Management
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiovascular Health and Disease Prevention
- Radiation Dose and Imaging
- Pericarditis and Cardiac Tamponade
Institut Cardiovasculaire Paris Sud
2016-2025
Hôpital Privé Jacques Cartier
2016-2025
Assistance Publique – Hôpitaux de Paris
2002-2025
Université Paris Cité
2025
Siemens (France)
2024-2025
Hôpital américain de paris
2025
Inserm
2025
Générale de Santé
2015-2024
Siemens Healthcare (Germany)
2024
Texas Cardiac Arrhythmia
2021
The clinical value of percutaneous coronary intervention (PCI) for chronic total occlusions (CTOs) is not established by randomized trials. This study should compare the benefit PCI vs. optimal medical therapy (OMT) on health status in patients with at least one CTO.Three hundred and ninety-six were enrolled a prospective randomized, multicentre, open-label, controlled trial to treatment OMT 2:1 randomization ratio. primary endpoint was change assessed Seattle angina questionnaire (SAQ)...
Abstract Background Patients with non-left-main coronary bifurcation lesions are usually best treated a stepwise provisional approach. However, patients true left main stem have been shown in one dedicated randomized study to benefit from systematic dual stent implantation. Methods and results Four hundred sixty-seven requiring intervention were recruited the EBC MAIN 11 European countries. aged 71 ± 10 years; 77% male. randomly allocated layered strategy (n = 230) or approach 237). The...
Background: Sizing for transcatheter aortic valve implantation in bicuspid valves (BAV) remains controversial. Methods and Results: The aim of the BAVARD (Bicuspid Aortic Valve Anatomy Relationship With Devices) retrospective registry is to capture sizing ratios used BAV analyze second-generation prostheses geometry postimplantation. About 101 patients with along available pre- post-transcatheter multidetector computed tomography were compared 88 tricuspid (TAV) patients. Preprocedural...
Background— Bicuspid aortic valve (BAV) is regarded as a relative contraindication to transcatheter implantation attributable the risk of uneven expansion bioprosthesis. The purpose this study was evaluate efficacy and safety in patients with BAV. Methods Results— Of 470 included our prospective database (October 2006–January 2012), 229 consecutive undergoing both echocardiography multidetector computed tomography were analyzed. We compared clinical outcomes vs without In series patients,...
Background— For the treatment of coronary bifurcation lesions, a provisional strategy is superior to systematic 2-stent techniques for most lesions. However, complex anatomies with large side branches (SBs) significant ostial disease length are considered by expert consensus warrant technique upfront. This view has not been scientifically assessed. Methods and Results— Symptomatic patients caliber true lesions (SB diameter ≥2.5 mm) (≥5 were randomized either T-stent or dual stent culotte...
A 1-year follow-up, polymer-free metallic stent coated with biolimus-A9 followed by 1-month dual antiplatelet therapy is safer and more effective than a bare-metal (BMS) for patients high risk of bleeding.This study analyzed 2-year outcomes to determine whether these benefits are maintained.In prospective, multicenter, double-blind trial, we randomized 2,466 bleeding receive drug-coated (DCS) or BMS therapy. The primary safety endpoint was composite cardiac death, myocardial infarction,...
To assess the effects of 1- or ≥3-month dual antiplatelet therapy (DAPT) in high bleeding risk (HBR) patients who received biodegradable-polymer sirolimus-eluting stents for complex percutaneous coronary intervention (PCI) and/or acute syndrome (ACS).In MASTER DAPT trial, 3383 underwent non-complex (abbreviated DAPT, n = 1707; standard 1676) and 1196 588; 608) PCI. Co-primary outcomes at 335 days were net adverse clinical events [NACE; composite all-cause death, myocardial infarction,...
Transoesophageal echocardiography (TEE) is considered the gold standard method for annulus measurement in transcatheter aortic valve implantation (TAVI). However, computed tomography (CT) has potential advantages compared to TEE. We sought assess impact of CT-guided sizing on post-procedural regurgitation (AR).We procedural characteristics and clinical outcomes patients undergoing either TEE-guided or TAVI. Among 350 consecutive TAVI recipients, mean age was 83.2 ± 6.4 years logistic...
Although annulus rupture is one of the most severe complications transcatheter aortic valve implantation (TAVI), incidence and mechanism this complication remain unclear. Out 387 consecutive TAVI cases in our institution, was 1.0% (4/387). The first two patients died because hemodynamic collapse due to tamponade on day 0. Both surviving had undergone preprocedural multidetector computed tomography which revealed large calcifications epicardial fat part annulus. In both cases, occurred after...
Transcatheter aortic valve implantation (TAVI) in patients with poor peripheral vessels still remains problematic, as the transapical approach is not always feasible and sometimes associated myocardial damage, bleeding, post-procedural chest pain pleural effusion. In order to address these issues, we adopted recently introduced transaortic (TAo) approach. The purpose of this study was evaluate efficacy safety TAo-TAVI using both Sapien XT CoreValve according VARC criteria.Of 492 (October...
Background: The durability of transcatheter aortic bioprosthetic valves is a crucial issue, but data are scarce, especially beyond 5 years follow-up. We aimed to assess long-term (7 years) structural valve deterioration (SVD) and failure valves. Methods Results: Consecutive patients with at least 5-year follow-up available undergoing implantation from April 2002 December 2011 in French centers were included. Incidence SVD defined according newly standardized criteria the European Association...
Prospective data about transcatheter aortic valve implantation (TAVI) in bicuspid (BAV) patients are limited.