A5102959286- Acute Myocardial Infarction Research
- Cardiac Imaging and Diagnostics
- Blood Pressure and Hypertension Studies
- Coronary Interventions and Diagnostics
- Cardiac Valve Diseases and Treatments
- Sodium Intake and Health
- Cardiac Arrest and Resuscitation
- Cardiac Arrhythmias and Treatments
- Cardiac Structural Anomalies and Repair
- Infective Endocarditis Diagnosis and Management
- Cardiac Health and Mental Health
- Cardiac pacing and defibrillation studies
- Cardiac electrophysiology and arrhythmias
- Antiplatelet Therapy and Cardiovascular Diseases
- ECG Monitoring and Analysis
- Hormonal Regulation and Hypertension
- Takotsubo Cardiomyopathy and Associated Phenomena
- Renal function and acid-base balance
- Mechanical Circulatory Support Devices
- Health Systems, Economic Evaluations, Quality of Life
- Atrial Fibrillation Management and Outcomes
- Cardiomyopathy and Myosin Studies
- Cardiovascular Syncope and Autonomic Disorders
- Vascular Anomalies and Treatments
- Coronary Artery Anomalies
Ascension Providence Hospital
2020-2024
Providence Hospital
2009-2024
Stanford Health Care
2017-2023
Piedmont Atlanta Hospital
2018-2022
Providence Hospital
2009-2021
Centennial Medical Center
2020
Providence Park Hospital
2018
Michigan State University
2017
Providence College
2005-2011
Wayne State University
2009
Renal denervation (RDN) has demonstrated clinically relevant reductions in blood pressure (BP) among individuals with uncontrolled hypertension despite lifestyle intervention and medications. The safety effectiveness of alcohol-mediated RDN have not been formally studied this indication.
BACKGROUND: The SPYRAL HTN-ON MED (Global Clinical Study of Renal Denervation With the Symplicity Spyral Multi-electrode System in Patients Uncontrolled Hypertension Absence Antihypertensive Medications)trial showed significant office and nighttime systolic blood pressure (BP) reductions patients with hypertension following renal denervation (RDN) compared sham-control patients, despite similar 24-hour BP reductions. We antihypertensive medication changes among prespecified subpopulations....
The renin-angiotensin-aldosterone system plays a key role in blood pressure (BP) regulation and is the target of several antihypertensive medications. Renal denervation (RDN) thought to interrupt sympathetic-mediated neurohormonal pathway as part its mechanism action reduce BP. purpose this study was evaluate plasma renin activity (PRA) aldosterone before after RDN assess whether these baseline neuroendocrine markers predict response RDN. Analyses were conducted patients with confirmed...
The incidence of conduction disease requiring permanent pacemaker (PPM) implantation following aortic valve replacement (AVR) ranges from 3% to 6%. Data concerning the potential risks for PPM requirement associated with certain types have been conflicting and controversial. We sought evaluate prevalence, predictors implantation, dependency during follow-up in patients undergoing AVR.A total 214 consecutive AVR were studied retrospectively. A 207 included statistical analysis. Clinical...
National guidelines have been set to achieve door-to-balloon time (D2B) is less than 90 minutes improve outcomes for patients with STEMI. The purpose of this study see if a more aggressive approach utilizing prehospital ECGs could reperfusion times.The EMS personnel obtained 12-lead ECG during initial assessment in the field from chest pain. was immediately transmitted ER physician by cellular link computer receiving station. reviewed digital tracing. cardiac catheterization laboratory (CCL)...
Abstract Background In the randomized AMIHOT‐II trial, supersaturated oxygen [SSO 2 ] delivered into left anterior descending (LAD) artery via an indwelling intracoronary infusion catheter following primary percutaneous coronary intervention (PCI) significantly reduced infarct size in patients with ST‐segment elevation myocardial infarction (STEMI) but resulted a numerically higher incidence of safety events. Objectives The IC‐HOT study evaluated SSO therapy selectively to main (LMCA) for 60...
The purpose of our study was to evaluate the relative impact bivalirudin on bleeding outcomes associated with trans-radial interventions (TRI) in real world practice.Data for patients undergoing percutaneous coronary intervention (PCI) between January 2010 and March 2014 at 47 hospitals participating Blue Cross Shield Michigan Cardiovascular Consortium (BMC2) were utilized. Propensity matching used within cohorts defined by access site. use in-hospital evaluated Fisher's exact tests. Among...
Abstract Background Supersaturated oxygen (SSO 2 ) has recently been approved by the U.S. Food and Drug Administration for administration after primary percutaneous coronary intervention (pPCI) in patients with anterior ST‐segment elevation myocardial infarction (STEMI) based on its demonstration of infarct size reduction IC‐HOT study. Objectives To describe 1‐year clinical outcomes intracoronary SSO treatment pPCI STEMI. Methods was a prospective, open‐label, single‐arm study which 100...
Abstract An algorithm to lower time from first contact in the field by EMS personnel in‐hospital mechanical reperfusion is described. ECG tracings were telemetered via cellular phone an emergency room physician, who then activated cardiac catheterization call team bypass usual delays seen during ER triage. Seventy‐one ECGs sent interval October 2003 2004. Five (7.0%) failed transmit due failure of receive adequate signal. Sixty‐six patients (93.0%) had transmitted and six with ST elevation...
The use of intermittent outpatient dobutamine infusion has recently been studied as an alternative therapy modality for patients with refractory conges tive heart failure. We the arrhythmogenic effects outpa tient in two NYHA class IV received at 5mcg./kg./min. four hours per day eight week period. Ambulatory Holter monitoring was obtained during periods and compared to infusion-free periods. A significant increase complex ventricular- arrhythmias, including multifocal PVC's ventricu lar...
Papillary muscle rupture is one of the catastrophic mechanical complications following myocardial infarction. Rupture leads to acute mitral valve regurgitation, pulmonary edema, and cardiogenic shock. Survival dependent on prompt recognition surgical intervention.We present two cases where infarction was complicated by papillary resulting in severe regurgitation In both occurred within week Both patients did not receive coronary revascularization; patient presented late after onset chest...
A 54-year-old male developed ventricular fibrillation during right coronary angiography. Cough cardiopulmonary resuscitation was performed for 30 sec allowing the patient to remain alert and hemodynamically stable. is a simple, often overlooked technique that can be utilized in cardiac catheterization laboratory. © 1996 Wiley-Liss, Inc.
We sought to evaluate the feasibility and safety of catheter-based supersaturated oxygen (SSO2 ) delivery via left main coronary artery (LMCA) following primary percutaneous intervention (PCI).In multicenter, randomized AMIHOT-II trial, SSO2 delivered into proximal or mid anterior descending (LAD) an indwelling intracoronary infusion catheter in patients with acute ST-segment elevation myocardial infarction (STEMI) PCI significantly reduced infarct size but resulted a numerically higher...
Abstract Anesthesia–induced coronary vasospasm has been reported only rarely. We report a case, without previous cardiac history, in which immediately after anesthesia induction marked ST elevation was noted on the EKG monitor. Premature ventricular contractions as well nonsustained tachycardia were noted. These changes resolved nitroglycerin infusion and 75 mg of lidocaine given. A angiogram revealed normal arteries left ventriculogram. Ergonovine stimulation not performed. The patient...
The radiofrequency (RF) needle has been shown to improve transseptal puncture efficiency and safety compared mechanical needles. This study aimed investigate the use of VersaCross RF wire system (Baylis Medical) procedural left atrial appendage closure (LAAC) standard needle-based workflow.