Khaled M. Ziada

ORCID: 0000-0002-4074-793X
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About
Contact & Profiles
Research Areas
  • Coronary Interventions and Diagnostics
  • Acute Myocardial Infarction Research
  • Cardiac Imaging and Diagnostics
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Atrial Fibrillation Management and Outcomes
  • Cardiac Valve Diseases and Treatments
  • Venous Thromboembolism Diagnosis and Management
  • Cardiac, Anesthesia and Surgical Outcomes
  • Transplantation: Methods and Outcomes
  • Peripheral Artery Disease Management
  • Cerebrovascular and Carotid Artery Diseases
  • Heart Failure Treatment and Management
  • Blood Pressure and Hypertension Studies
  • Cardiovascular Health and Disease Prevention
  • Vascular Procedures and Complications
  • Renal and Vascular Pathologies
  • Cardiac and Coronary Surgery Techniques
  • Mechanical Circulatory Support Devices
  • Cardiac Arrhythmias and Treatments
  • Cardiac Arrest and Resuscitation
  • Cardiovascular Disease and Adiposity
  • Advanced MRI Techniques and Applications
  • Infective Endocarditis Diagnosis and Management
  • Cardiac Structural Anomalies and Repair
  • Organ Transplantation Techniques and Outcomes

Cleveland Clinic
2003-2025

Cleveland Clinic Lerner College of Medicine
2023-2024

Mayo Clinic in Arizona
2024

Tameside and Glossop Integrated Care NHS Foundation Trust
2023

Manchester University
2023

The Christie NHS Foundation Trust
2023

Manchester University NHS Foundation Trust
2023

University of Kentucky
2012-2021

Menoufia University
2021

Galveston College
2021

The morphological characteristics of coronary plaques in patients with stable versus unstable syndromes have been described vivo intravascular ultrasound, but the relationship between arterial remodeling and clinical presentation is not well known.We studied 85 46 using ultrasound before intervention. lesion site a proximal reference were analyzed. ratio (RR) was defined as external elastic membrane (EEM) area at to that site. Positive an RR >1.05 negative <0.95. Plaque (13.9+/-5.5...

10.1161/01.cir.101.6.598 article EN Circulation 2000-02-15

Most of our knowledge about atherosclerosis at young ages is derived from necropsy studies, which have inherent limitations. Detailed, in vivo data on individuals are limited. Intravascular ultrasonography provides a unique opportunity for characterization early clinically relevant context.Intravascular ultrasound was performed 262 heart transplant recipients 30.9+/-13.2 days after transplantation to investigate coronary arteries asymptomatic subjects. The donor population consisted 146 men...

10.1161/01.cir.103.22.2705 article EN Circulation 2001-06-05

10.1016/s0140-6736(17)32281-x article EN The Lancet 2017-08-28

Digoxin is frequently used for rate control of atrial fibrillation (AF). It has, however, been associated with increased mortality. remains unclear whether digoxin itself responsible the mortality (toxic drug effect) or it prescribed to sicker patients inherently higher due comorbidities. The goal our study was determine relationship between and in AF. association assessed enrolled AF Follow-Up Investigation Rhythm Management (AFFIRM) trial using multivariate Cox proportional hazards models....

10.1093/eurheartj/ehs348 article EN European Heart Journal 2012-11-27

Despite widespread use of platelet glycoprotein (GP) IIb/IIIa receptor inhibitors for percutaneous coronary interventions (PCI) bypass grafts, data supporting this strategy are lacking.

10.1161/01.cir.0000041250.89627.a9 article EN Circulation 2002-12-10

Background: Regional variations in reperfusion times and mortality patients with ST-segment–elevation myocardial infarction are influenced by differences coordinating care between emergency medical services (EMS) hospitals. Building on the Accelerator-1 Project, we hypothesized that time to could be further reduced enhanced regional efforts. Methods: Between April 2015 March 2017, worked 12 metropolitan regions across United States 132 percutaneous coronary intervention–capable hospitals 946...

10.1161/circulationaha.117.032446 article EN Circulation 2017-11-15

Abstract Aims To assess the contemporary trends in aortic stenosis (AS) interventions USA before and after introduction of transcatheter valve implantation (TAVI). Methods results We utilized National-Inpatient-Sample to temporal incidence, cost, outcomes AS between 1 January 2003 31 December 2016. During study’s period, increased from 96 137 per 100 000 individuals &amp;gt; 60 years old, P &amp;lt; 0.001. In-hospital expenditure on $2.28 billion $4.33 2016 Among patients who underwent...

10.1093/eurheartj/ehz568 article EN European Heart Journal 2019-07-25
James Slater David J. Maron Philip G. Jones Sripal Bangalore Harmony R. Reynolds and 95 more Zhuxuan Fu Gregg W. Stone Ruth Kirby Judith S. Hochman John A. Spertus Kreton Mavromatis Jason Linefsky Todd Q. Miller Subhash Banerjee Jonathan Newman Robert Donnino Muhamed Sarić Khaled Abdul-Nour Peter Stone James J. Jang Gennie Yee Steven Weitz Suzanne V. Arnold James H. O’Keefe Michael D. Shapiro Steven Fein Mikhail Torosoff Radmila Lyubarova Sulagna Mookherjee Krzysztof Drzymalski Edward O. McFalls Santiago García Stefan Bertog Rizwan A. Siddiqui Areef Ishani Ronnell A. Hansen Michel G. Khouri Jonathan Goldberg Richard S. Goldweit Ronny Cohen Brooks Mirrer Victor J. Navarro David E. Winchester Marvin W. Kronenberg Christopher McFarren John F. Heitner Ira Dauber Charles R. Cannan Sriram Sudarshan Puja K. Mehta Michael McDaniel Stamatios Lerakis Arshed A. Quyyumi Nanette K. Wenger Chester M. Hedgepeth Heather Hurlburt Alan Rosen Zakir Sahul Steve Leung Hassan Reda Khaled M. Ziada Sampoornima Setty Rajat S. Barua Fadi G. Hage James E. Davies Massoud A. Leesar Jaekyeong Heo Amy Iskandrian Firas Al Solaiman Satinder P. Singh Khaled Dajani Mohammad El‐Hajjar Paul Der Mesropian Joseph Sacco Brian McCandless Marisa Orgera Mandeep S. Sidhu Imran Arif Hanan Kerr Jorge F. Trejo Gerald F. Fletcher Gary E. Lane Lynn M. Neeson Pragnesh Parikh Peter Pollak Brian P. Shapiro Kevin Landolfo Anthony Gemignani Daniel J. O’Rourke Judith Meadows Jason T. Call Joseph Hannan Robert M. Bojar Deepti Kumar John Mukai Edward T. Martin Gabriel Vorobiof Alec J. Moorman Scott Kinlay Robert J. Hamburger

BACKGROUND: The appropriate use criteria for revascularization of stable ischemic heart disease have not been evaluated using randomized data. Using data from the ISCHEMIA trial (International Study Comparative Health Effectiveness with Medical and Invasive Approaches; July 2012 to January 2018, 37 countries), health status benefits an invasive strategy over a conservative one were examined within scenarios. METHODS: Among 1833 participants mapped 36 scenarios, symptom was assessed Seattle...

10.1161/circoutcomes.124.010849 article EN Circulation Cardiovascular Quality and Outcomes 2025-02-26

Coronary artery disease is the major cause of late cardiac allograft failure. However, few data exist regarding natural history changes in intimal and external elastic membrane (EEM) areas after heart transplantation.In 38 transplant recipients, serial intravascular ultrasound examinations were performed 3.7+/-2.2 weeks transplantation annually thereafter for 5 years. In 59 coronary arteries, we compared 135 matched segments among studies. each segment, images digitized at 1-mm intervals,...

10.1161/hc3101.093867 article EN Circulation 2001-08-07
Emmanouil S. Brilakis Robert Edson Deepak L. Bhatt Steven Goldman David R. Holmes and 95 more Sunil V. Rao Kendrick Shunk Bavana V. Rangan Kreton Mavromatis Kodangudi B. Ramanathan Anthony A. Bavry Santiago García Faisal Latif Ehrin J. Armstrong Hani Jneid T. Conner Todd H. Wagner Judit Karácsonyi Lauren Uyeda Beverly Ventura Aaron Alsleben Ying Lü Mei‐Chiung Shih Subhash Banerjee Bina Ahmed D Michelle Ratliff Mark J. Ricciardi Mark Sheldon Milton V. Icenogle Richard L. Snider Amer Ardati Brahmajee K. Nallamothu Claire S. Duvernoy Daniel S. Menees Hitinder S. Gurm Michael P. Thomas Paul Grossman Kristine Owen On Topaz Gautam Kumar Kreton Mavromatis Peter C. Block David A. Zidar Hiram G. Bezerra Jonathan Goldberg José Ortiz Joseph Jozic Mohammed Osman Nadia Rosenthal Sahil A. Parikh Tom Lassar Albert W. Chan Arun Kumar Kul Aggarwal Tillmann Cyrus Emmanouil S. Brilakis Jerrold Grodin Subhash Banerjee Brack Hattler Ehrin J. Armstrong Ivan P. Casserly John C. Messenger Michael Kim R. Kevin Rogers Stephen W. Waldo Thomas Tsai Kenneth G. Morris Mitchell W. Krucoff Sunil V. Rao Thomas J. Povsic W. Schuyler Jones Anthony A. Bavry Calvin Choi Ki Park Jayson Liu Biswajit Kar David Paniagua Hani Jneid Jeffrey A. Breall Islam Bolad Rita Mukerji Roopa Subbarao Ahmed Abdel‐Latif David C. Booth Khaled M. Ziada Lawrence Rajan Abdul Hakeem Barry F. Uretsky Mayank Agrawal Rajesh Sachdeva Zubair Ahmed Jesse McGee Kodangudi B. Ramanathan Rahman Shah Alok Sharma Edward O. McFalls Rizwan Siddiqui Santiago García Selçuk Adabağ Stefan Bertog

10.1016/s0140-6736(18)30801-8 article EN The Lancet 2018-05-01
Harmony R. Reynolds Derek D. Cyr C. Noel Bairey Merz Leslee J. Shaw Bernard R. Chaitman and 95 more William E. Boden Karen P. Alexander Yves Rosenberg Sripal Bangalore Gregg W. Stone Claes Held John A. Spertus Kaatje Goetschalckx O.L. Bockeria Jonathan Newman Jeffrey S. Berger Ahmed Elghamaz Renato D. Lópes James K. Min Daniel S. Berman Michael H. Picard Raymond Y. Kwong Robert A. Harrington Boban Thomas Sean M. O’Brien David J. Maron Judith S. Hochman Kreton Mavromatis Jason Linefsky Todd Q. Miller Subhash Banerjee Harmony R. Reynolds Jonathan Newman Sripal Bangalore Robert Donnino Lawrence M. Phillips Muhamed Sarić Khaled Abdul‐Nour Peter H. Stone James J. Jang Gennie Yee Steven Weitz Suzanne V. Arnold James H. O’Keefe Michael D. Shapiro Mohammad El‐Hajjar Mandeep S. Sidhu Steven Fein Mikhail Torosoff Radmila Lyubarova Sulagna Mookherjee Krzysztof Drzymalski Edward O. McFalls Santiago García Stefan Bertog Rizwan A. Siddiqui Areef Ishani Ronnell A. Hansen Michel G. Khouri Jonathan Goldberg Richard S. Goldweit Ronny Cohen Brooks Mirrer Victor J. Navarro David E. Winchester Marvin W. Kronenberg Philip Rogal Christopher McFarren John F. Heitner Ira Dauber Charles R. Cannan Sriram Sudarshan Puja K. Mehta Michael McDaniel Stamatios Lerakis Arshed A. Quyyumi Nanette K. Wenger Chester M. Hedgepeth Heather Hurlburt Alan Rosen Zakir Sahul David T. Booth Steve Leung Ahmed Abdel‐Latif Hassan Reda Khaled M. Ziada Sampoornima Setty Rajat S. Barua Fadi G. Hage Christiano Caldeira James E. Davies Massoud A. Leesar Jaekyeong Heo Amy Iskandrian Firas Al Solaiman Satinder P. Singh Khaled Dajani Mohammad El‐Hajjar Paul Der Mesropian Joseph Sacco

Women with chronic coronary disease are generally older than men and have more comorbidities but less atherosclerosis. We explored sex differences in revascularization, guideline-directed medical therapy, outcomes among patients ischemia on stress testing, without invasive management.

10.1161/jaha.122.029850 article EN cc-by-nc-nd Journal of the American Heart Association 2024-02-27

Background —Transplant coronary artery disease is a combination of atherosclerosis transmitted from the donor and new lesions allograft vasculopathy. We sought to determine morphological characteristics vasculopathy differentiate it donor-transmitted with serial intravascular ultrasound. Methods Results —Intravascular ultrasound examination was performed in 93 patients at 27.2±15.0 369.7±23.9 days after transplantation. The maximally minimally diseased sites were selected each segment as...

10.1161/01.cir.98.24.2672 article EN Circulation 1998-12-15

Importance Patients with ST-segment elevation myocardial infarction (STEMI) living in rural settings often have worse clinical outcomes compared their urban counterparts. Whether this discrepancy is due to characteristics or delays timely reperfusion primary percutaneous coronary intervention (PPCI) fibrinolysis unclear. Objective To assess process metrics and among patients STEMI across the US. Design, Setting, Participants This cross-sectional multicenter study analyzed data for 70 424...

10.1001/jamacardio.2022.2774 article EN JAMA Cardiology 2022-08-31
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