Khaled M. Ziada
- Coronary Interventions and Diagnostics
- Acute Myocardial Infarction Research
- Cardiac Imaging and Diagnostics
- Antiplatelet Therapy and Cardiovascular Diseases
- Atrial Fibrillation Management and Outcomes
- Cardiac Valve Diseases and Treatments
- Venous Thromboembolism Diagnosis and Management
- Cardiac, Anesthesia and Surgical Outcomes
- Transplantation: Methods and Outcomes
- Peripheral Artery Disease Management
- Cerebrovascular and Carotid Artery Diseases
- Heart Failure Treatment and Management
- Blood Pressure and Hypertension Studies
- Cardiovascular Health and Disease Prevention
- Vascular Procedures and Complications
- Renal and Vascular Pathologies
- Cardiac and Coronary Surgery Techniques
- Mechanical Circulatory Support Devices
- Cardiac Arrhythmias and Treatments
- Cardiac Arrest and Resuscitation
- Cardiovascular Disease and Adiposity
- Advanced MRI Techniques and Applications
- Infective Endocarditis Diagnosis and Management
- Cardiac Structural Anomalies and Repair
- Organ Transplantation Techniques and Outcomes
Cleveland Clinic
2003-2025
Cleveland Clinic Lerner College of Medicine
2023-2024
Mayo Clinic in Arizona
2024
Tameside and Glossop Integrated Care NHS Foundation Trust
2023
Manchester University
2023
The Christie NHS Foundation Trust
2023
Manchester University NHS Foundation Trust
2023
University of Kentucky
2012-2021
Menoufia University
2021
Galveston College
2021
The morphological characteristics of coronary plaques in patients with stable versus unstable syndromes have been described vivo intravascular ultrasound, but the relationship between arterial remodeling and clinical presentation is not well known.We studied 85 46 using ultrasound before intervention. lesion site a proximal reference were analyzed. ratio (RR) was defined as external elastic membrane (EEM) area at to that site. Positive an RR >1.05 negative <0.95. Plaque (13.9+/-5.5...
Most of our knowledge about atherosclerosis at young ages is derived from necropsy studies, which have inherent limitations. Detailed, in vivo data on individuals are limited. Intravascular ultrasonography provides a unique opportunity for characterization early clinically relevant context.Intravascular ultrasound was performed 262 heart transplant recipients 30.9+/-13.2 days after transplantation to investigate coronary arteries asymptomatic subjects. The donor population consisted 146 men...
Digoxin is frequently used for rate control of atrial fibrillation (AF). It has, however, been associated with increased mortality. remains unclear whether digoxin itself responsible the mortality (toxic drug effect) or it prescribed to sicker patients inherently higher due comorbidities. The goal our study was determine relationship between and in AF. association assessed enrolled AF Follow-Up Investigation Rhythm Management (AFFIRM) trial using multivariate Cox proportional hazards models....
Despite widespread use of platelet glycoprotein (GP) IIb/IIIa receptor inhibitors for percutaneous coronary interventions (PCI) bypass grafts, data supporting this strategy are lacking.
Background: Regional variations in reperfusion times and mortality patients with ST-segment–elevation myocardial infarction are influenced by differences coordinating care between emergency medical services (EMS) hospitals. Building on the Accelerator-1 Project, we hypothesized that time to could be further reduced enhanced regional efforts. Methods: Between April 2015 March 2017, worked 12 metropolitan regions across United States 132 percutaneous coronary intervention–capable hospitals 946...
Abstract Aims To assess the contemporary trends in aortic stenosis (AS) interventions USA before and after introduction of transcatheter valve implantation (TAVI). Methods results We utilized National-Inpatient-Sample to temporal incidence, cost, outcomes AS between 1 January 2003 31 December 2016. During study’s period, increased from 96 137 per 100 000 individuals &gt; 60 years old, P &lt; 0.001. In-hospital expenditure on $2.28 billion $4.33 2016 Among patients who underwent...
BACKGROUND: The appropriate use criteria for revascularization of stable ischemic heart disease have not been evaluated using randomized data. Using data from the ISCHEMIA trial (International Study Comparative Health Effectiveness with Medical and Invasive Approaches; July 2012 to January 2018, 37 countries), health status benefits an invasive strategy over a conservative one were examined within scenarios. METHODS: Among 1833 participants mapped 36 scenarios, symptom was assessed Seattle...
Coronary artery disease is the major cause of late cardiac allograft failure. However, few data exist regarding natural history changes in intimal and external elastic membrane (EEM) areas after heart transplantation.In 38 transplant recipients, serial intravascular ultrasound examinations were performed 3.7+/-2.2 weeks transplantation annually thereafter for 5 years. In 59 coronary arteries, we compared 135 matched segments among studies. each segment, images digitized at 1-mm intervals,...
Women with chronic coronary disease are generally older than men and have more comorbidities but less atherosclerosis. We explored sex differences in revascularization, guideline-directed medical therapy, outcomes among patients ischemia on stress testing, without invasive management.
Background —Transplant coronary artery disease is a combination of atherosclerosis transmitted from the donor and new lesions allograft vasculopathy. We sought to determine morphological characteristics vasculopathy differentiate it donor-transmitted with serial intravascular ultrasound. Methods Results —Intravascular ultrasound examination was performed in 93 patients at 27.2±15.0 369.7±23.9 days after transplantation. The maximally minimally diseased sites were selected each segment as...
Importance Patients with ST-segment elevation myocardial infarction (STEMI) living in rural settings often have worse clinical outcomes compared their urban counterparts. Whether this discrepancy is due to characteristics or delays timely reperfusion primary percutaneous coronary intervention (PPCI) fibrinolysis unclear. Objective To assess process metrics and among patients STEMI across the US. Design, Setting, Participants This cross-sectional multicenter study analyzed data for 70 424...