A5019344131- Transplantation: Methods and Outcomes
- Mechanical Circulatory Support Devices
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac Valve Diseases and Treatments
- Cardiac Structural Anomalies and Repair
- Cardiac and Coronary Surgery Techniques
- Organ Transplantation Techniques and Outcomes
- Pain Management and Treatment
- Cardiac Imaging and Diagnostics
- Anesthesia and Neurotoxicity Research
- Infective Endocarditis Diagnosis and Management
- Cardiac Arrest and Resuscitation
- Congenital Heart Disease Studies
- Aortic Disease and Treatment Approaches
- Thermal Regulation in Medicine
- Intensive Care Unit Cognitive Disorders
- Cardiovascular Function and Risk Factors
- Atrial Fibrillation Management and Outcomes
- Cardiac Arrhythmias and Treatments
- Coronary Interventions and Diagnostics
- Acute Kidney Injury Research
- Pulmonary Hypertension Research and Treatments
- Cardiac pacing and defibrillation studies
- Renal Transplantation Outcomes and Treatments
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
Mayo Clinic in Florida
2015-2024
WinnMed
2015-2024
Jacksonville College
2013-2024
Mayo Clinic in Arizona
2021-2024
Mayo Clinic Hospital
2022-2023
Mayo Clinic
2013-2014
Augusta University
2003-2007
Duke University
1997-2005
Duke Medical Center
1996-2005
Duke University Hospital
1997-2005
Acute renal failure requiring dialysis (ARF-D) occurs in 1.5% of patients following cardiac surgery, and remains a cause major morbidity mortality. While some preoperative risk factors have been characterized, the influence intraoperative on occurrence ARF surgery is less well understood.Preoperative data 2843 consecutive adult undergoing with cardiopulmonary bypass (CPB) from February 1, 1995 to 1997 were recorded entered into computerized database. Two definitions employed: (i) defined as...
The importance of perioperative cognitive decline has long been debated. We recently demonstrated a significant correlation between and long-term dysfunction. Despite this association, some still question the these changes in function to quality life patients their families. purpose our investigation was determine association dysfunction after cardiac surgery.After institutional review board approval patient informed consent, 261 undergoing surgery with cardiopulmonary bypass were enrolled...
Neurocognitive dysfunction is a common complication after cardiac surgery. We evaluated in this prospective study the effect of rewarming rate on neurocognitive outcome hypothermic cardiopulmonary bypass (CPB). After IRB approval and informed consent, 165 coronary artery graft surgery patients were studied. Patients received similar surgical anesthetic management until from (28°–32°C) CPB. Group 1 (control;n = 100) was warmed conventional manner (4°–6°C gradient between nasopharyngeal CPB...
Neurocognitive dysfunction is a common complication after cardiac surgery. We evaluated in this prospective study the effect of rewarming rate on neurocognitive outcome hypothermic cardiopulmonary bypass (CPB). After IRB approval and informed consent, 165 coronary artery graft surgery patients were studied. Patients received similar surgical anesthetic management until from (28°–32°C) CPB. Group 1 (control;n = 100) was warmed conventional manner (4°–6°C gradient between nasopharyngeal CPB...
To evaluate sternal healing, complications, and costs after sternotomy closure with rigid plate fixation or wire cerclage.This prospective, single-blinded, multicenter trial randomized 236 patients at 12 US centers the time of to either (n = 116) cerclage 120). The primary endpoint, healing 6 months, was evaluated by a core laboratory using computed tomography 6-point scale (greater scores represent greater healing). Secondary endpoints included complications from through months.Rigid...
BACKGROUND: The appropriate use criteria for revascularization of stable ischemic heart disease have not been evaluated using randomized data. Using data from the ISCHEMIA trial (International Study Comparative Health Effectiveness with Medical and Invasive Approaches; July 2012 to January 2018, 37 countries), health status benefits an invasive strategy over a conservative one were examined within scenarios. METHODS: Among 1833 participants mapped 36 scenarios, symptom was assessed Seattle...
Abstract Aims We sought to investigate the outcomes of heart transplant patients supported with Impella 5.5 temporary mechanical circulatory support. Methods and results Patient demographics, perioperative data, hospital timeline, haemodynamic parameters were followed during initial admission, support, post‐transplant period. Vasoactive‐inotropic score, primary graft failure, complications recorded. Between March 2020 2021, 16 advanced failure underwent left ventricular assist device support...
Objective To evaluate gender-related differences in quality of life (QOL) and cognitive function 1 year after coronary artery bypass surgery (CABG) adjusting for known baseline differences. Materials Methods Two hundred eighty patients (96 women 184 men) underwent neurocognitive QOL evaluation at (preoperatively) CABG. Multivariable linear regression was used to assess the relationship gender follow-up function. Measures were IADL, DASI, work activities (SF-36), social activities, support,...
Although transmyocardial laser revascularization (TMR) has provided symptomatic relief of angina over the short term, long-term efficacy procedure is unknown. Angina symptoms as assessed independently by class and Seattle Questionnaire (SAQ) were prospectively collected up to 7 years after TMR.Seventy-eight patients with severe not amenable conventional treated a CO(2) laser. Their mean age was 61+/-10 at time treatment. Preoperatively, 66% had unstable angina, 73% >/=1 myocardial...
Renal dysfunction is a serious complication after coronary bypass surgery with cardiopulmonary (CABG). Because duration of (CPB) associated renal outcome, it has been proposed that avoidance CPB off-pump (OPCAB) may reduce perioperative insult. We therefore tested the hypothesis OPCAB less postoperative compared CABG surgery. With IRB approval, we gathered data for 690 primary elective patients (OPCAB, 55; CABG, 635). Perioperative change in creatinine clearance (DCrCl) was calculated by...
Background Renal dysfunction after cardiac surgery occurs in up to 8% of patients and is associated with major increases morbidity, mortality, cost. Genetic polymorphisms have been implicated as a factor the progression chronic renal disease, but genetic basis for development acute impairment has not investigated. The authors therefore tested hypothesis that apolipoprotein E alleles are different postoperative changes serum creatinine surgery. Methods performed prospective observational...
Neurocognitive decline is a continuing source of morbidity after cardiac surgery. Atrial fibrillation occurs often surgery and has been linked to adverse neu-rologic events. We sought determine whether postoperative atrial was associated with cognitive dysfunction. Four-hundred-eleven patients were enrolled receive battery neurocognitive tests both preoperatively 6 wk elective coronary artery bypass graft test scores separated into four domains, composite index (the mean the domain scores)...
Neurocognitive decline is a continuing source of morbidity after cardiac surgery. Atrial fibrillation occurs often surgery and has been linked to adverse neu-rologic events. We sought determine whether postoperative atrial was associated with cognitive dysfunction. Four-hundred-eleven patients were enrolled receive battery neurocognitive tests both preoperatively 6 wk elective coronary artery bypass graft test scores separated into four domains, composite index (the mean the domain scores)...
The present study aimed to compare the clinical outcomes of heart transplant patients whose donor hearts were preserved with SherpaPak controlled cold organ system versus conventional ice storage technique.All undergoing transplantation at our center between January 2019 and April 2021 divided into two groups according technique used during preservation transport. first group consisted 34 temperature patients, second 47 where three bags was utilized transportation. compared based on...
Abstract Backgound Infections of the left ventricular assist device (LVAD) driveline are a dreaded complication that results in high mortality and morbidity. Method We retrospectively reviewed five consecutive patients with severe continuous‐flow LVAD (HVAD, Heartmate 2, 3) infection. These infections, which developed on an average 960.4 ± 843.9 days after placement, were refractory to systemic antibiotics local wound care. All treated extensive surgical debridement, installation absorbable...