A5056744945- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac and Coronary Surgery Techniques
- Cardiac Arrest and Resuscitation
- Anesthesia and Neurotoxicity Research
- Mechanical Circulatory Support Devices
- Intensive Care Unit Cognitive Disorders
- Cardiac Structural Anomalies and Repair
- Cardiac Valve Diseases and Treatments
- Aortic Disease and Treatment Approaches
- Aortic aneurysm repair treatments
- Thermal Regulation in Medicine
- Cardiac Ischemia and Reperfusion
- Heart Failure Treatment and Management
- Cardiac tumors and thrombi
- Hemodynamic Monitoring and Therapy
- Cardiac pacing and defibrillation studies
- Traumatic Brain Injury and Neurovascular Disturbances
- Sarcoma Diagnosis and Treatment
- Magnesium in Health and Disease
- Cardiac electrophysiology and arrhythmias
- Cardiac Imaging and Diagnostics
- Trauma Management and Diagnosis
- Pericarditis and Cardiac Tamponade
- Cutaneous Melanoma Detection and Management
- Cardiovascular Issues in Pregnancy
Institutul de Urgenţă pentru Boli Cardiovasculare "Prof.Dr. C.C. Iliescu"
2024
Charleston Area Medical Center
2024
CAMC Health Education and Research Institute
2024
University of Nevada, Las Vegas
2015
Flinders Medical Centre
2015
Flinders University
2015
University of Michigan–Ann Arbor
2015
Wake Forest University
2015
Baystate Medical Center
2015
Tufts University
2015
Neurocognitive dysfunction is a common complication after cardiac surgery. We evaluated in this prospective study the effect of rewarming rate on neurocognitive outcome hypothermic cardiopulmonary bypass (CPB). After IRB approval and informed consent, 165 coronary artery graft surgery patients were studied. Patients received similar surgical anesthetic management until from (28°–32°C) CPB. Group 1 (control;n = 100) was warmed conventional manner (4°–6°C gradient between nasopharyngeal CPB...
Temperature is a well-known modulator of experimental cerebral injury. We hypothesized that hyperthermia would be associated with worsened cognitive outcome after coronary artery bypass graft surgery (CABG).Three hundred consenting patients undergoing cardiopulmonary for CABG had hourly postoperative temperatures recorded. The degree was determined by using the maximum temperature within first 24 hours as well calculating area under curve >37 degrees C. Patients underwent battery testing...
Neurocognitive dysfunction is a common complication after cardiac surgery. We evaluated in this prospective study the effect of rewarming rate on neurocognitive outcome hypothermic cardiopulmonary bypass (CPB). After IRB approval and informed consent, 165 coronary artery graft surgery patients were studied. Patients received similar surgical anesthetic management until from (28°–32°C) CPB. Group 1 (control;n = 100) was warmed conventional manner (4°–6°C gradient between nasopharyngeal CPB...
Background Despite significant advances in cardiopulmonary bypass (CPB) technology, surgical techniques, and anesthetic management, central nervous system complications occur a large percentage of patients undergoing surgery requiring CPB. Many centers are switching to normothermic CPB because shorter operating room times improved myocardial protection. The authors hypothesized that, compared with normothermia, hypothermic would result superior neurologic neurocognitive function after...
In Brief BACKGROUND: Clevidipine is an ultrashort-acting, third-generation IV dihydropyridine calcium channel blocker that exerts rapid and titratable arterial blood pressure reduction, with fast termination of effect due to metabolism by tissue esterases. As arterial-selective vasodilator, clevidipine reduces peripheral vascular resistance directly, without dilating the venous capacitance bed. this randomized, double-blind, placebo-controlled multicenter trial we evaluated efficacy...
Extracellular glutamate is elevated following brain ischemia or trauma and contributes to neuronal injury. We tested the hypothesis that magnesium sulfate (MgSO4, 3 mM) protects against metabolic failure caused by excitotoxic exposure. Rat cortical neuron preparations treated in medium already containing a physiological concentration of Mg2+ (1 could be segregated based on their response (100 µM). Type I responded with decrease small transient increase oxygen consumption rate (OCR). II...
To improve our understanding of the evidence-based literature supporting temperature management during adult cardiopulmonary bypass, The Society Thoracic Surgeons, Cardiovascular Anesthesiology and American ExtraCorporeal Technology tasked authors to conduct a review peer-reviewed literature, including 1) optimal site for monitoring, 2) avoidance hyperthermia, 3) peak cooling gradient rate, 4) warming rewarming rate. Authors adopted College Cardiology/American Heart Association method...
The use of left ventricular (LV) assist devices (LVADs) can improve performance and recovery failing human hearts.Following our alpha-adrenergic receptor work, we hypothesized that mechanical unloading in patients with low output syndrome LV failure would yield similar results beta-adrenergic receptors ((beta)AR), being increased numbers intra-myocytic relocalization.(beta)AR density localization were investigated by fluorescence deconvolution microscopy compared at LVAD insertion removal 13...
Atracurium is sometimes used for muscle relaxation in patients undergoing mechanical ventilation. Use of atracurium high doses or a long period time has raised the possibility accumulation laudanosine, breakdown product known to cause seizure activity animals. The objective this report was see if laudanosine and had occurred patient who received long-term, relatively high-dose infusion atracurium.Case report. 38 days, at rates ranging from 0.3 0.96 mg/kg/hr. An electroencephalogram (EEG)...
Abstract Background Patients with spontaneous coronary artery dissection may require surgical revascularization. Reports on the management of this pathology are primarily limited to classic bypass grafting via sternotomy cardiopulmonary bypass, although a number reports alternatives also exist. Methods We describe case robotic completely endoscopic surgery using daVinci® Si™ system in patient dissection. Results Robotically assisted single left internal mammary was carried out successfully...