A5061400884- Cardiac Valve Diseases and Treatments
- Cardiac Imaging and Diagnostics
- Coronary Interventions and Diagnostics
- Acute Myocardial Infarction Research
- Cardiac Arrhythmias and Treatments
- Cardiac Structural Anomalies and Repair
- Coronary Artery Anomalies
- Cardiovascular Function and Risk Factors
- Infective Endocarditis Diagnosis and Management
- Atrial Fibrillation Management and Outcomes
- Congenital Heart Disease Studies
- Inflammatory Biomarkers in Disease Prognosis
- Cardiac electrophysiology and arrhythmias
- Venous Thromboembolism Diagnosis and Management
- Cardiovascular Issues in Pregnancy
- Cardiac pacing and defibrillation studies
- Vascular anomalies and interventions
- Cardiac tumors and thrombi
- Cardiovascular Health and Disease Prevention
- Blood Pressure and Hypertension Studies
- Adipokines, Inflammation, and Metabolic Diseases
- Antiplatelet Therapy and Cardiovascular Diseases
- Aortic Disease and Treatment Approaches
- Cardiovascular Disease and Adiposity
- Cardiomyopathy and Myosin Studies
Gülhane Askerî Tıp Akademisi
2003-2020
Sağlık Bilimleri Üniversitesi
2019
Turkish Armed Forces
2007-2016
Military Medical Academy
2007-2016
Kasımpaşa Asker Hastanesi
2014
Military Hospital
2014
Eskişehir City Hospital
2014
Institute of Cardiology
2006-2011
Naval Academy
2007
Cleveland Clinic
2001-2003
Objectives To determine the effects of nebivolol on oxidative stress, insulin resistance, adiponectin and plasma soluble P-selectin levels in hypertensive patients comparison with metoprolol. Material methods Eighty newly diagnosed grade 1 hypertension according to European Society Hypertension Cardiology guidelines were enrolled this prospective, blinded, randomized study. Seventy-two completed After baseline assessment, each patient was randomly allocated a 5 mg daily dose (n = 37, 20...
Endothelial dysfunction is regarded as the initial lesion in development of atherosclerosis. Endocan, previously called endothelial cell–specific molecule 1 (ESM-1), a new candidate immunoinflammatory marker that may be associated with cardiometabolic risk factors. Therefore, we assessed serum levels endocan newly diagnosed patients untreated essential hypertension (HT). A total 18 HT and 23 normotensive control participants were included study. Serum levels, carotid intima–media thickness...
High level of circulating red cell distribution width (RDW) and neutrophil/lymphocyte (N/L) ratio may reflect ongoing vascular inflammation play an important role in pathophysiology hypertension. We evaluate the effects nebivolol metoprolol on RDW N/L new essential hypertensive patients. After baseline assessment, 72 patients were randomly allocated to 5 mg/d (n = 37, 20 men) or 100 35, 18 treated for 6 months. Blood pressure (BP), heart rate (HR), RDW, measured before after treatment. BP...
Atherosclerosis plays an important role in the etiopathogenesis of coronary artery ectasia (CAE). Inflammation markers may play a part pathogenesis CAE. We aimed to assess association between CAE and neutrophil-lymphocyte (N/L) ratio. Consecutive eligible patients (n = 181) were divided into 3 groups: with CAE, those newly diagnosed disease (CAD), normal angiogram. The N/L ratio mean platelet volume (MPV) measured as automated complete blood count. There no statistically significant...
Behçet disease (BD) is associated with endothelial dysfunction and chronic inflammation. The neutrophil-lymphocyte (N/L) ratio carotid intima-media thickness (cIMT) are markers of inflammation vascular risk, respectively. We assessed the relationship between cIMT values N/L in BD (65 patients 62 control participants). There were statistically significant differences ratios group (P < .001). moderate positive correlations value, C-reactive protein, BD. Receiver-operating characteristic curve...
Coronary artery disease is the major cause of late cardiac allograft failure. However, few data exist regarding natural history changes in intimal and external elastic membrane (EEM) areas after heart transplantation.In 38 transplant recipients, serial intravascular ultrasound examinations were performed 3.7+/-2.2 weeks transplantation annually thereafter for 5 years. In 59 coronary arteries, we compared 135 matched segments among studies. each segment, images digitized at 1-mm intervals,...
Neutrophils and lymphocytes (N/L) ratio carotid intima–media thickness (C-IMT) value have been studied as new predictors of cardiovascular risk. We aimed to investigate N/L C-IMT in patients with cardiac syndrome X (CSX) compare coronary artery disease (CAD) normal participants. A total 288 participants were enrolled the study. The compared among 3 groups. There no statistically significant differences levels between CSX CAD was found significantly increased CAD, control group. Patients had...
Vascular inflammation plays an important role in the pathophysiology of hypertension and high levels endocan may reflect ongoing vascular hypertensive patients. In present hypothesis-generating study, we aimed at investigating comparative effects amlodipine valsartan on newly diagnosed The study population consisted 37 untreated patients who were randomized to two treatment arms. After baseline assessment, each patient was randomly allocated either 10 mg daily (n = 18, 7 males) or 160 19, 3...
Psoriasis is associated with an increased risk of atherosclerosis. Endothelial dysfunction the critical early step in process atherogenesis, and it commonly investigated by measuring arterial stiffness. We aimed to investigate relationship between stiffness high-sensitivity C-reactive protein (hsCRP) patients psoriasis. A total 32 psoriasis 35 other skin diseases were included study. The hsCRP levels measurements compared. Arterial was significantly different 2 groups (P = .01). not duration...
The red cell distribution width-platelet ratio (RPR), a novel inflammatory marker is currently used to predict inflammation in chronic diseases. It may be associated with adverse outcomes among artery disease but its prognostic value ST-segment elevation myocardial infarction (STEMI) treated primary percutaneous coronary intervention (PCI) has not been fully investigated. There no data regarding the association between RPR and in-hospital major cardiovascular events (MACEs). This study...
No-reflow is of prognostic value in ST-segment elevation myocardial infarction (STEMI) but has not been extensively investigated young patients. Young patients with STEMI admitted within 12 hours from symptom onset and treated by primary percutaneous coronary intervention (pPCI) were recruited. Patients classified into 2 groups based on postintervention thrombolysis (TIMI) flow grade; no-reflow: TIMI grade 0, 1 or (group 1; n = 27; 21 men, mean age: 42 ± 4 years); angiographic success: 3 2;...
Background: The slow coronary flow (SCF) is characterized by angiographically normal or near-normal arteries with delayed progression of the contrast agent into distal vasculature. We aimed to investigate neutrophil-to-lymphocyte (N/L) ratio and carotid intima-media thickness (CIMT) value in patients SCF compared newly diagnosed artery disease (CAD) patients. Materials Methods: enrolled 60 consecutive SCF, 68 CAD, 72 association between thrombolysis myocardial infarction frame count, CIMT,...
Cardiac syndrome X (CSX) is characterised by angina-like chest pain, a positive stress test, and normal coronary arteries. Increased red cell distribution width (RDW) level may be indicative of an underlying inflammatory state.To investigate RDW in patients with CSX compare having artery disease (CAD) subjects.245 subjects (79 CSX, 81 CAD, 85 controls) were enrolled the study. The group consisted anginal ischaemia on noninvasive test angiogram.CAD was defined as ≥ 50% stenosis at least one...
Background: Prolongation of P-wave times and increase dispersion (PWD) were shown to be independent predictors atrial fibrillation (AF). Angiotensin II receptor blockers (AARBs) angiotensin-converting enzyme inhibitors (ACEIs) have beneficial effects on conduction times. However, there are not enough data about the comparative those drugs onPWD. Hypothesis: We aimed compare telmisartan ramipril PWD after 6-month treatment in hypertensive patients. Methods: In all, 100 newly diagnosed...
Atherosclerosis plays an important role in the etiopathogenesis of coronary artery ectasia (CAE). The relationship between total bilirubin (TBil) and carotid intima media thickness (cIMT) patients with CAE has not been fully investigated. Hence, we evaluated TBil levels cIMT 142 consecutive eligible CAE, newly diagnosed disease (CAD), normal arteries. There were no significant differences (P = .772) .791) CAD groups. Bilirubin significantly lower both groups compared to controls < .01). was...
Prehypertension is characterized by an increased cardiovascular risk and prevalence of target organ damage compared with the pure normotensive state. The present study was designed to assess in prehypertensive subjects possible relationships between early left ventricular dysfunction, vascular inflammation aortic stiffness. population consisted 31 untreated (age: 34 ± 6 years, mean SD) age-matched controls. Left function assessed echocardiography, distensibility parameters were derived from...