A5053871832- Inflammatory Biomarkers in Disease Prognosis
- Cardiovascular Health and Disease Prevention
- Cardiac Valve Diseases and Treatments
- Cardiovascular Disease and Adiposity
- Adipokines, Inflammation, and Metabolic Diseases
- Cardiovascular Function and Risk Factors
- Venous Thromboembolism Diagnosis and Management
- Blood Pressure and Hypertension Studies
- Cardiac Imaging and Diagnostics
- Cardiac Structural Anomalies and Repair
- Infective Endocarditis Diagnosis and Management
- Biomarkers in Disease Mechanisms
- Acute Myocardial Infarction Research
- Cardiac tumors and thrombi
- Inflammation biomarkers and pathways
- Kawasaki Disease and Coronary Complications
- Atrial Fibrillation Management and Outcomes
- Coronary Artery Anomalies
- Congenital Heart Disease Studies
- Inflammasome and immune disorders
- Cardiovascular and Diving-Related Complications
- Pulmonary Hypertension Research and Treatments
- Heart Failure Treatment and Management
- Ocular Diseases and Behçet’s Syndrome
- Cardiac Arrhythmias and Treatments
Malatya Devlet Hastanesi
2018-2022
GTx (United States)
2021
Gülhane Askerî Tıp Akademisi
2012-2017
Turkish Armed Forces
2011-2016
Eskişehir City Hospital
2013-2016
Military Medical Academy
2012-2016
GATA Haydarpaşa Eğitim Hastanesi
2016
Military Hospital
2014-2015
Etimesgut Asker Hastanesi
2014
Trakya University
2014
Endothelial dysfunction is regarded as the initial lesion in development of atherosclerosis. Endocan, previously called endothelial cell–specific molecule 1 (ESM-1), a new candidate immunoinflammatory marker that may be associated with cardiometabolic risk factors. Therefore, we assessed serum levels endocan newly diagnosed patients untreated essential hypertension (HT). A total 18 HT and 23 normotensive control participants were included study. Serum levels, carotid intima–media thickness...
Psoriasis vulgaris is an inflammatory disease characterized by epidermal hyperproliferation, leucocyte adhesion molecule expression and infiltration. associated with increased risk of cardiovascular disease. Endothelial dysfunction widely regarded as being the initial process in development atherosclerosis. Human endothelial cell‐specific molecule‐1 (endocan) a novel human molecule. Previous studies suggested that endocan may be marker. To investigate relationship between serum levels both...
High level of circulating red cell distribution width (RDW) and neutrophil/lymphocyte (N/L) ratio may reflect ongoing vascular inflammation play an important role in pathophysiology hypertension. We evaluate the effects nebivolol metoprolol on RDW N/L new essential hypertensive patients. After baseline assessment, 72 patients were randomly allocated to 5 mg/d (n = 37, 20 men) or 100 35, 18 treated for 6 months. Blood pressure (BP), heart rate (HR), RDW, measured before after treatment. BP...
Atherosclerosis plays an important role in the etiopathogenesis of coronary artery ectasia (CAE). Inflammation markers may play a part pathogenesis CAE. We aimed to assess association between CAE and neutrophil-lymphocyte (N/L) ratio. Consecutive eligible patients (n = 181) were divided into 3 groups: with CAE, those newly diagnosed disease (CAD), normal angiogram. The N/L ratio mean platelet volume (MPV) measured as automated complete blood count. There no statistically significant...
Behçet disease (BD) is associated with endothelial dysfunction and chronic inflammation. The neutrophil-lymphocyte (N/L) ratio carotid intima-media thickness (cIMT) are markers of inflammation vascular risk, respectively. We assessed the relationship between cIMT values N/L in BD (65 patients 62 control participants). There were statistically significant differences ratios group (P < .001). moderate positive correlations value, C-reactive protein, BD. Receiver-operating characteristic curve...
Neutrophils and lymphocytes (N/L) ratio carotid intima–media thickness (C-IMT) value have been studied as new predictors of cardiovascular risk. We aimed to investigate N/L C-IMT in patients with cardiac syndrome X (CSX) compare coronary artery disease (CAD) normal participants. A total 288 participants were enrolled the study. The compared among 3 groups. There no statistically significant differences levels between CSX CAD was found significantly increased CAD, control group. Patients had...
High levels of circulating Von Willebrand factor (vWf) and increased neutrophil to lymphocyte (N/L) ratio may reflect vascular inflammation in hypertensive patients. In present study, we aimed investigate the effects valsartan as an angiotensin II receptor antagonist amlodipine a calcium channel blocker on vWf N/L patients with essential hypertension. Patients were randomized one following intervention protocols: (amlodipine, 5–10 mg/day) group A (n = 20 mean age 51.85 ± 11.32 y)...
Cardiac syndrome X is characterized by angina-like chest pain, a positive stress test, and normal coronary arteries. A patient's mean platelet volume, which potentially reflects function activity, associated with atherosclerosis endothelial dysfunction. The aim of the present study was to evaluate volumes patients cardiac X, those artery disease subjects.Two hundred thirty-six subjects (76 78 disease, 82 controls) were enrolled in study. All evaluated detailed medical history, physical...
Vascular inflammation plays an important role in the pathophysiology of hypertension and high levels endocan may reflect ongoing vascular hypertensive patients. In present hypothesis-generating study, we aimed at investigating comparative effects amlodipine valsartan on newly diagnosed The study population consisted 37 untreated patients who were randomized to two treatment arms. After baseline assessment, each patient was randomly allocated either 10 mg daily (n = 18, 7 males) or 160 19, 3...
Behcet disease (BD) and recurrent aphthous stomatitis (RAS) are systemic inflammatory diseases, but the exact pathogenesis of both diseases is unknown. Mean platelet volume (MPV) an indicator activation. The aim this study was to investigate MPV levels in patients with BD, RAS, healthy participants. A total 61 60 controls were included study. erythrocyte sedimentation rate BD RAS groups significantly higher than control (P < .001). In group as well group, activity does not affect MPV. may be...
Psoriasis is associated with an increased risk of atherosclerosis. Endothelial dysfunction the critical early step in process atherogenesis, and it commonly investigated by measuring arterial stiffness. We aimed to investigate relationship between stiffness high-sensitivity C-reactive protein (hsCRP) patients psoriasis. A total 32 psoriasis 35 other skin diseases were included study. The hsCRP levels measurements compared. Arterial was significantly different 2 groups (P = .01). not duration...
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease of unknown etiology. A major cause morbidity and mortality in SLE accelerated atherosclerosis. Endothelial-specific molecule 1 (endocan) potential predictor vascular events expressed response to inflammatory cytokines endothelial cells. We investigated the relationship between endocan carotid intima–media thickness (cIMT) as marker early included 44 women with healthy controls. Disease severity was evaluated using Activity...
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Although mean platelet volume (MPV) is an independent correlate of impaired angiographic reperfusion and 6-month mortality in ST-segment elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (pPCI), there less data regarding the association between distribution width (PDW) in-hospital major adverse cardiovascular events (MACEs). A total 306 patients STEMI pPCI were evaluated. No reflow was defined as a post-PCI thrombolysis (TIMI) flow grade 0, 1, or...
The red cell distribution width-platelet ratio (RPR), a novel inflammatory marker is currently used to predict inflammation in chronic diseases. It may be associated with adverse outcomes among artery disease but its prognostic value ST-segment elevation myocardial infarction (STEMI) treated primary percutaneous coronary intervention (PCI) has not been fully investigated. There no data regarding the association between RPR and in-hospital major cardiovascular events (MACEs). This study...