A5075284065- Catalytic Processes in Materials Science
- Catalysis and Oxidation Reactions
- Dendrimers and Hyperbranched Polymers
- RNA Interference and Gene Delivery
- Cardiac Imaging and Diagnostics
- Advanced Drug Delivery Systems
- Protein purification and stability
- Drug Solubulity and Delivery Systems
- Hepatitis B Virus Studies
- Education and Learning Interventions
- Liver Disease Diagnosis and Treatment
- Hepatitis C virus research
- Monoclonal and Polyclonal Antibodies Research
- Transgenic Plants and Applications
- Diabetes Treatment and Management
- Nanoparticle-Based Drug Delivery
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Education, Safety, and Science Studies
- Plant tissue culture and regeneration
- Hemodynamic Monitoring and Therapy
- Dialysis and Renal Disease Management
- Protein Interaction Studies and Fluorescence Analysis
- Peptidase Inhibition and Analysis
- Catalysts for Methane Reforming
- Cardiovascular Disease and Adiposity
Pusan National University Hospital
2023-2025
Dankook University
2023-2024
Weatherford College
2019-2024
Soonchunhyang University
2023-2024
Bucheon University
2024
Pusan National University
2024
University of Ulsan
2018-2023
Ulsan College
2018-2023
Ulsan University Hospital
2018-2023
National Academy of Agricultural Science
2023
Data on the relationship between triglyceride glucose (TyG) index and coronary artery calcification (CAC) progression is limited. This longitudinal study evaluated association of TyG with CAC in asymptomatic adults.We enrolled 12,326 Korean adults who had at least two evaluations. The was determined using ln (fasting triglycerides [mg/dL] × fasting [mg/dL]/2). defined as a difference ≥ 2.5 square roots (√) baseline follow-up calcium score (CACS) (Δ√transformed CACS). Annualized Δ√transformed...
Atherosclerotic cardiovascular (CV) events commonly occur in individuals with a low CV risk burden. This study evaluated the ability of triglyceride glucose (TyG) index to predict subclinical coronary artery disease (CAD) asymptomatic subjects without traditional factors (CVRFs).This retrospective, cross-sectional, and observational association TyG CAD 1250 (52.8 ± 6.5 years, 46.9% male) CVRFs (defined as systolic/diastolic blood pressure ≥ 140/90 mmHg; fasting ≥126 mg/dL; total cholesterol...
Abstract Idiopathic pulmonary fibrosis (IPF) is characterized by aberrant lung remodeling and the excessive accumulation of extracellular matrix (ECM) proteins. In a previous study, we found that levels ornithine aminotransferase (OAT), principal enzyme in proline metabolism pathway, were increased lungs patients with IPF. However, precise role played OAT pathogenesis IPF not yet clear. The mechanism which affects fibrogenesis was assessed vitro using OAT-overexpressing OAT-knockdown...
The reverse water gas shift (RWGS) reaction catalyzed by barium zirconate-based perovskite-type catalysts doped with Y, Zn, and Ce was investigated in terms of activities chemical stabilities various catalysts. All the showed stable performances for RWGS at 600 °C 5 h, particular, BaZr0.8Y0.16Zn0.04O3 (BZYZ) catalyst an outstanding activity average CO2 conversion 37.5% a CO selectivity 97%. Insertion additional into BZYZ structure did not have any positive effect on catalytic reaction, even...
Optimal adherence to nucleoside analogue treatment is necessary achieve undetectable levels of hepatitis B virus (HBV) DNA in patients with chronic (CHB), and prevent cirrhotic complications. However, any large long-term follow-up study has not been investigated the effect entecavir (ETV) on specific liver-related events (LREs), namely, hepatocellular carcinoma (HCC), complications, mortality.This was a 10-year longitudinal observational treatment-naïve CHB who received ETV treatment. The...
Abstract Using a chemical vapor deposition method with regulated sample temperatures under ambient pressure conditions, we were able to fully decorate the internal structure of mesoporous Al 2 O 3 bead (~1 mm in particle diameter) iron oxide nanoparticles (with mean lateral size less than 1 nm). The oxide-decorated showed high CO oxidation reactivity, even at room temperature. Very little deactivation activity was observed increasing reaction time ~100 °C. Additionally, this catalyst...
Nano differential scanning fluorimetry (nanoDSF) is a high-throughput protein stability screening technique that simultaneously monitors unfolding and aggregation properties. The thermal of immunoglobulin G (IgG) was investigated in three different buffers (sodium acetate, sodium citrate, phosphate) ranging from pH 4 to 8. In all buffers, the midpoint temperature (Tm) showed tendency increase as increased, but propensity depending on buffer species. best against obtained acetate below 4.6....
Tenofovir alafenamide (TAF) has shown less favorable effect on lipids compared to tenofovir disoproxil fumarate (TDF) in clinical trials. However, data regarding these outcomes patients with chronic hepatitis B (CHB) are scarce. Therefore, this study aimed evaluate the of TAF lipid CHB.A total 237 TAF-treated CHB TDF, inactive CHB, and non-hepatitis virus (HBV)-infected control groups using propensity score matching (PSM).Following PSM, each analysis was conducted cohorts via 70:140...
Environmental concerns, especially global warming, have prompted efforts to reduce greenhouse gas emissions. Healthcare systems, including anesthesia practices, contribute these Inhalation anesthetics a significant environmental impact, with desflurane being the most concerning because of its high warming potential. This study aimed educate anesthesiologists on impact inhalation and assess changes in awareness practice patterns, specifically reducing use. included data from patients who...
Hyperphosphorylated tau is a main component of neurofibrillary tangles, pathological hallmark Alzheimer's disease (AD). There evidence that various protein kinases are involved in hyperphosphorylation. However, little known about AD-related stimuli activates kinases. We investigated the role zinc, metal AD pathology, phosphorylation. Zinc increased phosphorylation serine 214 (S214) human wild-type tau1-441-expressing SH-SY5Y cells. The was inhibited by suppressing Ras-Raf/mitogen-activated...
Several reports have shown that thymoquinone (TQ) effectively attenuates angiogenesis in cancer cells, resulting suppression of tumor growth. However, it is not yet clear whether TQ reduces hypoxia-inducible factor-1α (HIF-1α) expression hypoxic cells. Here, we found was a novel HIF-1α inhibitor through hypoxia response element (HRE)-luciferase assay-based large screening by using 502 natural compounds containing chemical library. reduced protein levels renal cells; however, did affect the...
Abstract Background Atherogenic lipoprotein profile of plasma is an important risk factor for atherosclerosis. The atherogenic index (AIP) has been suggested as a novel marker Hypothesis AIP useful advanced subclinical coronary artery disease (CAD) in subjects without overt renal dysfunction. Methods A total 6928 with estimated glomerular filtration rate > 60 mL/minutes/1.73 m 2 evaluated by computed tomography angiography (CCTA) health check‐up were included. relation to CAD (heavy...
Background/Aims: Low-level viremia (LLV) after nucleos(t)ide analog treatment was presented as a possible cause of hepatocellular carcinoma (HCC) in patients with chronic hepatitis B (CHB). However, detailed information on patients’ adherence the real world lacking. This study aimed to evaluate effects LLV HCC development, mortality, and cirrhotic complications among according their entecavir (ETV) treatment.Methods: We performed retrospective observational analysis data from 894 consecutive...