A5090019639- Diabetes Treatment and Management
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Liver Disease Diagnosis and Treatment
- Metabolism, Diabetes, and Cancer
- Diabetes Management and Research
- Pancreatic function and diabetes
- Nutrition and Health in Aging
- Cardiovascular Disease and Adiposity
- Lipoproteins and Cardiovascular Health
- Cardiovascular Function and Risk Factors
- Adipokines, Inflammation, and Metabolic Diseases
- Cardiac Imaging and Diagnostics
- Diabetes and associated disorders
- Pharmacology and Obesity Treatment
- Body Composition Measurement Techniques
- Cardiovascular Health and Disease Prevention
- Diet and metabolism studies
- Diet, Metabolism, and Disease
- Alcohol Consumption and Health Effects
- Peptidase Inhibition and Analysis
- Diabetes Management and Education
- Adipose Tissue and Metabolism
- Bariatric Surgery and Outcomes
- Heart Failure Treatment and Management
- Renal Transplantation Outcomes and Treatments
University of Ulsan
2016-2025
Asan Medical Center
2016-2025
Ulsan College
2016-2025
Seoul National University Bundang Hospital
2024
University of Virginia
2019-2023
Soongsil University
2022
Mammazentrum Hamburg
2017
Korea Atomic Energy Research Institute
2016
Hannam University
2013
Zero to Three
2012
The National Health Insurance Service (NHIS) recently signed an agreement to provide limited open access the databases within Korean Diabetes Association for benefit of subjects with diabetes. Here, we present history, structure, contents, and way use data procurement in (NHI) system researchers.The NHIS Korea is a single-payer program mandatory all residents Korea. three main healthcare programs NHI, Medical Aid, long-term care insurance (LTCI) 100% coverage population. has adopted...
Abstract Background The atherogenic index of plasma (AIP) is composed triglycerides and high-density lipoprotein cholesterol a novel marker for assessing the risk atherogenicity cardiometabolic health. An association between AIP greater frequency major adverse cardiovascular events (MACEs) in patients with type 2 diabetes mellitus high (CV) disease has been reported. However, only few studies have examined correlation CV general populations. We thus aimed to evaluate relationship diseases...
Background: Although the complex roles of macrophages in myocardial injury are widely appreciated, function neutrophils nonischemic cardiac pathology has received relatively little attention. Methods: To examine regulation and pressure overload–induced hypertrophy, mice underwent treatment with Ly6G antibody to deplete then were subjected transverse aortic constriction. Results: Neutrophil depletion diminished constriction–induced hypertrophy inflammation preserved function. Myeloid...
Abstract Despite the strong influence of gut microbiota on atherosclerosis, a causal relationship between atherosclerosis pathophysiology and is still unverified. This study was performed to determine impact pathogenesis caused by genetic deficiency. To elucidate pathogenesis, an atherosclerosis-prone mouse model (C1q/TNF-related protein 9-knockout (CTRP9-KO) mice) generated. The microbial compositions CTRP9-KO WT control mice were compared. Fecal transplantation (FMT) confirm association...
Background/Aims: To investigate whether non-alcoholic fatty liver disease (NAFLD) in individuals without generalized obesity is associated with visceral fat (VFO), sarcopenia, and/or myosteatosis.Methods: This cross-sectional analysis included 14,400 (7,470 men) who underwent abdominal computed tomography scans during routine health examinations. The total muscle area (TAMA) and skeletal (SMA) at the 3<sup>rd</sup> lumbar vertebral level were measured. SMA was divided into normal...
This study investigated trends in the prescription of antidiabetic medications for patients with type 2 diabetes, focusing on changing patterns prescriptions and cost drugs during last 10 years. Retrospective data diabetes aged 30 years or older were analyzed using information from National Health Information Database collected by Insurance Service Korea January 2002 to December 2013. We identified who had at least one service claim each year period. The prescribing was fixed-dose...
This study sought to investigate whether the metabolically healthy obese (MHO) phenotype is associated with an increased risk of incident type 2 diabetes in a Korean population and, if so, systemic inflammation affects this MHO individuals.The comprised 36 135 Koreans without diabetes. Participants were stratified by body mass index (cutoff value, 25.0 kg/m(2)) and metabolic health state (assessed using Adult Treatment Panel-III criteria). High-sensitive C-reactive protein (hsCRP) was used...
Sarcopenia has emerged as an important risk factor for nonalcoholic fatty liver disease (NAFLD). Although aging is the main cause of sarcopenia, longitudinal association between age-related body composition changes and NAFLD development not been fully investigated. Thus, we evaluated whether increased fat mass or decreased muscle independent incident NAFLD.We conducted a retrospective cohort study involving 4,398 initially NAFLD-free subjects who underwent routine health examinations during...
Representative data on the secular trends in cardiovascular disease (CVD) are limited Asian populations with diabetes. We aimed to estimate temporal complications using Korean nationwide whole population-based claims subjects and without diabetes.Type 2 diabetes was defined as a current medication history of anti-diabetic drugs presence International Classification Diseases (ICD)-10 codes (E11-E14) diagnosis. compared 8-year rates six [i.e., ischemic heart disease, acute myocardial...
Since December 2019, countries around the world have been struggling with a novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Case series reported that people obesity experience more disease 2019 (COVID-19). During COVID-19 pandemic, tended to gain weight because of environmental factors imposed by quarantine policies, such as decreased physical activity and increased consumption unhealthy food. Mechanisms postulated explain association between obesity....
The triglyceride glucose (TyG) index, a product of and fasting glucose, is reliable marker for insulin resistance. We aimed to investigate the association between TyG-related markers coronary artery calcification (CAC) progression. enrolled 1145 asymptomatic participants who underwent repeated CAC score measurements during routine health examinations. Homeostasis model assessment resistance (HOMA-IR), TyG TyG-BMI (body mass index), TyG-WC (waist circumference) were calculated. Progression...
This study aimed to determine the optimal cut-off values of visceral fat area (VFA) and visceral-to-subcutaneous ratio (VSR) for predicting incident type 2 diabetes mellitus (T2DM).A total 10,882 individuals (6,835 men; 4,047 women) free T2DM at baseline aged between 30 79 years who underwent abdominal computed tomography scan 2012 2013 as a part routine health check-ups were included followed. VFA, subcutaneous area, VSR on L3 vertebral level measured baseline.During median follow-up 4.8...
The triglyceride-glucose (TyG) index, the product of fasting triglycerides and glucose, is a useful cost-effective marker insulin resistance (IR). Furthermore, TyG index known IR screening tool in healthy young adults but not those with atherosclerotic cardiovascular disease (CVD). Thus, this study aimed to evaluate as predictor CVD adults.This enrolled 6,675,424 aged 20-39 years without from National Health Information Database. We categorized them by quartile 2009-2017. outcomes were...