A5027444148- Diabetes Treatment and Management
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Liver Disease Diagnosis and Treatment
- Diabetes Management and Research
- Metabolism, Diabetes, and Cancer
- Adipokines, Inflammation, and Metabolic Diseases
- Diet, Metabolism, and Disease
- Lipoproteins and Cardiovascular Health
- Adipose Tissue and Metabolism
- Pancreatic function and diabetes
- Diet and metabolism studies
- Cardiovascular Function and Risk Factors
- Peroxisome Proliferator-Activated Receptors
- Cardiovascular Disease and Adiposity
- Diabetes and associated disorders
- Diabetes Management and Education
- Regulation of Appetite and Obesity
- Bone Metabolism and Diseases
- Alcohol Consumption and Health Effects
- Pituitary Gland Disorders and Treatments
- Cancer, Lipids, and Metabolism
- Cardiac Imaging and Diagnostics
- Bone health and osteoporosis research
- Mobile Health and mHealth Applications
- Biomarkers in Disease Mechanisms
Korea Advanced Institute of Science and Technology
2021-2025
Kangbuk Samsung Hospital
2016-2025
Sungkyunkwan University
2016-2025
Soongsil University
2022-2025
Hanyang University Guri Hospital
2022-2025
Samsung Medical Center
2010-2024
CHA University
2022-2024
CHA Bundang Medical Center
2022-2024
University of Ulsan
2024
Asan Medical Center
2024
The National Health Insurance Service (NHIS) recently signed an agreement to provide limited open access the databases within Korean Diabetes Association for benefit of subjects with diabetes. Here, we present history, structure, contents, and way use data procurement in (NHI) system researchers.The NHIS Korea is a single-payer program mandatory all residents Korea. three main healthcare programs NHI, Medical Aid, long-term care insurance (LTCI) 100% coverage population. has adopted...
Abstract Background The triglyceride glucose (TyG) index is an inexpensive clinical surrogate marker for insulin resistance. However, the relationship between TyG and atherosclerotic cardiovascular disease (CVD) remains unclear. We evaluated CVD using a large-scale population dataset from National Health Information Database (NHID). Methods performed retrospective observational cohort study of 5,593,134 persons older than 40 years 2009 to 2017 NHID. divided participants into quartiles....
High-energy and long cycle lithium-sulfur (Li-S) pouch cells are limited by the insufficient capacities stabilities of their cathodes under practical electrolyte/sulfur (E/S), electrolyte/capacity (E/C), negative/positive (N/P) ratios. Herein, an advanced cathode comprising highly active Fe single-atom catalysts (SACs) is reported to form 320.2 W h kg-1 multistacked Li-S with total capacity ≈1 A level, satisfying low E/S (3.0), E/C (2.8), N/P (2.3) ratios high sulfur loadings (8.4 mg cm-2 )....
Abstract Objective To investigate the risk of non-alcoholic fatty liver disease (NAFLD) for cardiovascular and all cause death in patients with type 2 diabetes mellitus (T2DM). Design Nationwide population based study. Setting Longitudinal cohort study Korea. Participants 7 796 763 participants National Health Screening Programme 2009 were divided into three groups on NAFLD status: no (fatty index<30); grade 1 (30≤fatty index<60); index≥60). Median follow-up was 8.13 years. Main...
Summary Objective Body weight is a significant predictor of bone mass. Hormonal factors such as sex hormones, insulin, leptin and adiponectin are thought to play role in the mechanisms controlling association body fat mass with However, contradictory results have been reported for between serum adipocytokines mineral density (BMD). We therefore examined whether adipocytokine ghrelin levels, markers metabolism, associated BMD male adults. Patients measurements For 80 adults (average age 54·5...
An association between vitamin D status and sarcopenia has not been shown in a community-dwelling cohort, despite the well-documented relationship falls.Our objective was to investigate whether level is associated with older Koreans.The Fourth Korea National Health Nutrition Examination Survey Korean population conducted 2009.Participants included 1380 men 1789 women aged 50 yr or older.Serum 25-hydroxyvitamin [25(OH)D] PTH levels were measured. Sarcopenia defined as an appendicular skeletal...
We evaluated the association of regular physical exercise with presence non-alcoholic fatty liver disease (NAFLD) and enzymes in relation to obesity insulin resistance.A cross-sectional analysis was conducted 72,359 healthy Korean adults without diabetes who participated a comprehensive health check-up. Subjects have been exercising regularly (more than 3 times per week, at least for 30 minutes each time consecutive month) were categorized into group. All subjects deciles based on their body...
The effects of exendin-4 on Sirt1 expression as a mechanism reducing fatty liver have not been previously reported. Therefore, we investigated whether the beneficial treatment are mediated via in high-fat (HF) diet-induced obese C57BL/6J mice and related cell culture models. Exendin-4 decreased body weight, serum free acid (FA), triglyceride levels HF-induced mice. Histological analysis showed that reversed hepatic accumulation lipids inflammation. increased mRNA protein its downstream...
To evaluate whether there is a difference in the association between nonalcoholic fatty liver disease (NAFLD) and incident diabetes based on presence of impaired fasting glucose.A total 7,849 individuals (5,409 men 2,440 women) without diabetes, who underwent comprehensive health check-ups annually for 5 years, were categorized into four groups by glucose NAFLD at baseline. The was evaluated separately with normal glucose.For 4 incidence group 9.9% compared 3.7% non-NAFLD group,...
The Triglyceride Glucose Index (TyG index) is considered a surrogate marker of insulin resistance. aim this study to investigate whether the TyG index has predictive role in identifying individuals with high risk incident diabetes and compare it other indicators metabolic health. A total 2900 non-diabetic adults who attended five consecutive annual health check-ups at Kangbuk Samsung Hospital was divided into four subgroups using three methods: (1) baseline index; (2) obesity status (body...
Insulin resistance is suggested to have negative effects on cognition; however, results from large population studies are lacking. In this study, the potential relationships between triglyceride glucose (TyG) index, a simple surrogate marker of insulin resistance, and dementia were evaluated using large-scale dataset.This was retrospective, observational, cohort study data National Health Information Database 2009 2015 included 5,586,048 participants 40 years age or older. The TyG index used...
F-free, cost-effective 1 M NaBH 4 /glyme electrolytes induce SEI reconstruction, which converts the native oxide layer on sodium metal to a NaH-based layer. With /DEGDME, we achieved long-term cycling, high-power seawater batteries.
This study investigated the changes of fatty liver disease prevalence in general Korean population.This analyzed data from National Health Insurance Service 2009 to 2017 that included individuals aged 20 years or older who had undergone a medical health examination. Fatty was assessed using index (FLI). The severity defined by FLI cutoff, ≥30 as moderate, and ≥60 severe disease.The adults over with (FLI ≥60) increased 13.3% 15.5% (P for trend <0.001). increase prominent men (from 20.5%...
Metabolic syndrome is highly prevalent in the U.S. (age-adjusted prevalence of 23.7%) (1) and Korea (20.8% for men 26.9% women) (2). This well documented to increase risk developing type 2 diabetes cardiovascular diseases (CVDs) associated with an all-cause mortality (3–5). Physical inactivity, excessive weight gain, high alcohol intake, certain dietary factors have been identified as important modifiable metabolic its consequences (2,6,7). Smoking also a strong factor atherosclerosis CVD,...
Elevated intraocular pressure (IOP), a well-known risk factor for glaucoma, has recently been shown to be associated with some metabolic complications and obesity. We investigated the link between IOP disturbances, focusing especially on syndrome insulin resistance.Eye examinations, including measurement, were conducted 943 subjects (533 men 410 women). Body mass index (BMI), percent body fat, waist circumference, systolic diastolic pressure, fasting insulin, glucose, lipids, other...