A5061738110- Diabetes Management and Research
- Adipokines, Inflammation, and Metabolic Diseases
- Bone health and osteoporosis research
- Heat shock proteins research
- Bone Metabolism and Diseases
- Diet and metabolism studies
- Bone health and treatments
- Diabetes Treatment and Management
- Pituitary Gland Disorders and Treatments
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Health and Wellbeing Research
- Pain Mechanisms and Treatments
- Cancer, Hypoxia, and Metabolism
- ATP Synthase and ATPases Research
- Diabetes and associated disorders
- Thyroid Disorders and Treatments
- Metabolism, Diabetes, and Cancer
- Regulation of Appetite and Obesity
- Cell death mechanisms and regulation
- Thyroid Cancer Diagnosis and Treatment
- Diabetes Management and Education
- Oral and Maxillofacial Pathology
- Hormonal Regulation and Hypertension
- Peptidase Inhibition and Analysis
- Temporomandibular Joint Disorders
Wonkwang University
2012-2024
University of Utah
2021-2023
Kwangwoon University
2023
University of California, San Diego
2005-2022
Arizona State University
2015-2022
Hallym University
2012-2021
Hallym University Sacred Heart Hospital
2006-2017
Chuncheon Sacred Heart Hospital
2003-2015
Hallym Polytechnic University
2012-2013
Hallym University Medical Center
2010-2013
Summary Objective Body weight is a significant predictor of bone mass. Hormonal factors such as sex hormones, insulin, leptin and adiponectin are thought to play role in the mechanisms controlling association body fat mass with However, contradictory results have been reported for between serum adipocytokines mineral density (BMD). We therefore examined whether adipocytokine ghrelin levels, markers metabolism, associated BMD male adults. Patients measurements For 80 adults (average age 54·5...
Background/Aims Recent epidemiological studies revealed a striking inverse relationship between vitamin D levels, glucose intolerance/insulin resistance (IR), and cardiovascular disease. However, few interventional have evaluated the effect of supplementation on risk, such as IR arterial stiffness, in diabetes. We investigated role risk type 2 diabetes patients, including metabolic parameters, IR, stiffness. Methods enrolled patients who were taking antidiabetic medications or managed their...
Epidemiologic studies have shown that low vitamin D levels are associated with reduced insulin sensitivity and increased risk of developing type 2 diabetes mellitus (T2DM). However, there is little evidence supplementation improves glucose intolerance. We evaluated the glucose-lowering effect in Korean T2DM subjects. enrolled 158 patients who had stable glycemic control [hemoglobin A1c (HbA1c) <8.5%] less than 20 ng/mL. The participants were randomized into two groups: Placebo (100 mg daily...
The formation of titanium (Ti)-wear particles during the lifetime an implant is believed to be a major component loosening due debris-induced changes in bone cell function. Radiographic evidence indicates loss fixation at implant–bone interface, and we believe that accumulation Ti may act on bone-remodeling process impact both long- short-term implant-fixation strengths. To determine effects various sizes osteoblast function vivo , measured integration strength around Ti-pin implants...
Sleep Disturbances and Glucoregulation in Patients with Type 2 DiabetesWe investigated the frequency of sleep disturbances association between glucoregulation type diabetic patients.The 614 patients was using validated questionnaires.There were 381 male 233 female mean age 59.7 ± 11.1 yr; body mass index 24.9 4.4 kg/m ; HbA1c 7.8% 1.5%; duration diabetes 10.3 8.4 yr.The questionnaires revealed insomnia 48.2% while 8.5% reported excessive daytime sleepiness.A total 49% poor sleepers, 28.5%...
Summary Objective Osteoporosis is a growing health problem in males as well females. Sex hormones and insulin‐like growth factor‐I (IGF‐I) have been shown to be the major determinants male bone metabolism. Osteoprotegerin (OPG) recently identified cytokine that acts decoy receptor for activator of NF‐κB ligand (RANKL). OPG RANKL important regulators osteoclastogenesis. However, relationship between OPG‐RANKL system status human populations are unclear. Thus, aim this study was investigate...
Objective Hyperglycemia is not identified as a significant prognostic factor for idiopathic sudden sensorineural hearing loss in any literature. Therefore, we investigated the value of hyperglycemia predicting recovery. Study Design A retrospective cohort study. Setting Tertiary university hospital. Subjects and Methods Patients were classified into 3 groups according to their glucose tolerance using 75‐gram oral test hemoglobin A1c follows: (1) normal group, (2) prediabetes which included...
Background and Purpose Diabetes is associated with cognitive decline as well the development of dementia. Although mean blood glucose levels are typically used to assess status diabetic patients, variability also involved in manifestation macro- microvascular complications this population. Thus, present study sought determine whether visit-to-visit contributes patients type 2 diabetes. Methods The assessed 68 diabetes using several validated neuropsychological measures. All had no...
We designed a system for diabetes patients treated with glargine, long-acting insulin, to make an automatic adjustment of insulin dose based on glucose level data and provide the needed by using short message service (SMS). also compared who used our received conventional titration scheme.Included were 100 type 2 whose blood was suboptimally controlled their previous antidiabetes treatment. Each participant assigned either intervention or control group, each 50 patients, adaptive...
The influence of the novel heat shock protein 90 (hsp90) inhibitor NVP-AUY922 (AUY922) on anaplastic thyroid carcinoma (ATC) cells has not been investigated. effect AUY922 alone or in combination with histone deacetylase PXD101 survival ATC was evaluated. In cells, AUY922, compared 17-allylamino-17-demethoxygeldanamycin, herbimycin A and radicicol, potently lead to growth inhibition cell death cleavage caspase-3 poly (ADP-ribose) polymerase (PARP) concomitant changes expression hsp90 client...
Necrotizing fasciitis (NF) is an infection that spreads along the fascial planes, causing subcutaneous tissue death characterized by rapid progression, systemic toxicity, and even death. NF often appears as a red, hot, painful, swollen wound with ill-defined border. As infective process continues, local pain replaced numbness or analgesia. disease skin initially becomes pale, then mottled purple, finally, gangrenous. The ability of to move rapidly planes cause necrosis secondary its...
PURPOSE Chemerin has been suggested to be linked insulin resistance and type 2 diabetes mellitus (T2DM). However, the relationship between visceral adiposity chemerin levels remains unclear in subjects with T2DM. In this study, we investigated serum adiposity. MATERIALS AND METHODS This study included 102 newly diagnosed The relationships clinical biochemical parameters were examined. Multiple linear regression analysis was performed determine predictable factors of levels. RESULTS Serum...
Objectives The maxillary sinus mucosa is reported to recover preoperative sterility after floor elevation. However, when drainage of impaired, recovery can be delayed and sinusitis occur. Therefore, in this study, we investigated the correlations between anatomic variants that interrupt ostium incidence complication lifting. Materials Methods subjects are 81 patients who underwent lifting Wonkwang University Dental Hospital (Iksan, Korea). Computed tomography (CT) images were reviewed for...
This study aimed to explore the relation of immunoglobulin G4 (IgG4) clinical and laboratory characteristics patients newly diagnosed with Graves' disease (GD) without or ophthalmopathy (GO) analyze association IgG4 development grade GO in GD patients.Sixty-four 64 sex- age-matched euthyroid subjects were enrolled. Serum levels thyroid hormones, autoantibodies, G (IgG), measured, ophthalmological ultrasonographical evaluation was performed.In compared subjects, autoantibodies as well...