- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Acute Myocardial Infarction Research
- Cerebrovascular and Carotid Artery Diseases
- Antiplatelet Therapy and Cardiovascular Diseases
- Lipoproteins and Cardiovascular Health
- Cancer, Lipids, and Metabolism
- Peripheral Artery Disease Management
- Cardiovascular Function and Risk Factors
- Quantum Dots Synthesis And Properties
- Cardiac Valve Diseases and Treatments
- Cardiovascular Disease and Adiposity
- Cancer, Hypoxia, and Metabolism
- Atrial Fibrillation Management and Outcomes
- Vascular Procedures and Complications
- Chalcogenide Semiconductor Thin Films
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Congenital Heart Disease Studies
- Lipid metabolism and disorders
- Cardiac Arrhythmias and Treatments
- Gastric Cancer Management and Outcomes
- Blood Pressure and Hypertension Studies
- Radiomics and Machine Learning in Medical Imaging
- Bone health and osteoporosis research
- Sinusitis and nasal conditions
Chung-Ang University
2012-2025
Jeonbuk National University
2013-2024
Chung-Ang University Hospital
2015-2024
Korea University Medical Center
2018-2024
Ajou University
2011-2023
Green Cross International
2023
Green Cross (South Korea)
2023
Kangwon National University
2007-2021
Chonbuk National University Hospital
2012-2021
Brigham and Women's Hospital
2020-2021
Stent thrombosis (ST) is a serious complication of drug-eluting stent (DES) implantation regardless the timing (acute, subacute, or late). The correlates ST with DES are not yet completely elucidated.From total cohort 2974 consecutive patients treated since April 2003, we identified 38 who presented angiographic evidence (1.27%). occurred acutely in 5 patients, subacutely (< =30 days) 25 and late (>30 8 patients. clinical, angiographic, procedural variables these were compared remaining 2936...
Intravascular imaging-guided percutaneous coronary intervention (PCI) with intravascular ultrasound (IVUS) or optical coherence tomography (OCT) showed superior clinical outcomes compared angiography-guided PCI. However, the comparative effectiveness of OCT-guided and IVUS-guided PCI regarding is unknown.In this prospective, multicenter, open-label, pragmatic trial, we randomly assigned 2008 patients significant artery lesions undergoing in a 1:1 ratio to undergo either an The primary end...
Background— Ischemic postconditioning has been reported to reduce infarct size in patients with ST-segment–elevation myocardial infarction. However, cardioprotective effects of have not demonstrated a large-scale trial. Methods and Results— We performed multicenter, prospective, randomized, open-label, blinded end-point A total 700 undergoing primary percutaneous coronary intervention (PCI) for infarction within 12 hours after symptom onset were randomly assigned the group or conventional...
Abstract InP-based quantum dots (QDs) have attracted much attention for use in optical applications, and several types of QDs such as InP/ZnS, InP/ZnSeS, InP/GaP/ZnS been developed. However, early synthetic methods that involved rapid injection at high temperatures not able to reproducibly produce the required properties. They were also support commercialization efforts successfully. Herein, we introduce a simple method core/shell/shell via heating process. The reaction was completed within...
Prostaglandin E(2) (PGE(2)), the most abundant COX-2-derived prostaglandin found in colorectal cancer, promotes tumor cell proliferation and survival via multiple signaling pathways. However, role of PGE(2) hypoxia is not well understood. Here, we show a synergistic effect on enhancing angiopoietin-like protein 4 (ANGPTL4) expression that elevation ANGPTL4 cancer growth. induces at both mRNA levels under hypoxic conditions. Moreover, one receptors, namely EP1. Activation EP1 enhances...
Abstract We evaluated the diagnostic performance and generalizability of traditional machine learning deep models for distinguishing glioblastoma from single brain metastasis using radiomics. The training external validation cohorts comprised 166 (109 glioblastomas 57 metastases) 82 (50 32 patients, respectively. Two-hundred-and-sixty-five radiomic features were extracted semiautomatically segmented regions on contrast-enhancing peritumoral T2 hyperintense masks used as input data. For each...
Background The role of intravascular ultrasound (IVUS)-guided percutaneous coronary intervention (PCI) is still unclear in patients with acute myocardial infarction infarction. This study aimed to evaluate the long-term impact IVUS-guided PCI Methods and Results Among a total 13 104 infarction, enrolled Korea Acute Myocardial Infarction Registry-National Institutes Health, we selected who underwent second-generation drug-eluting stent implantation. primary outcome was risk target lesion...
Background. Coronary artery calcification (CAC) is an extensive and common complication in patients with end-stage renal disease (ESRD). The aim of this study was to assess prospectively the change CAC over a 2-year period identify factors that may be associated progression ESRD patients.
The combination of solution processable colloidal quantum dots (CQDs) and organic conjugated polymers has attracted growing interest in the past few years, because devices fabricated using this can have potentially low cost high efficiency. In paper, we propose a new device architecture multiply layered PbS CQD-sensitized photovoltaic cells. multiple layers CQDs were formed by repeated spin-coating oleic-acid-capped CQD 1 wt% 1,2-ethanedithiol (EDT) onto mesoporous (mp)-TiO2 as photoanode....
Background Studies on the pathophysiology of nasal polyps in human subjects have been limited; thus an animal model is needed. There increasing evidence supporting role Staphylococcus aureus enterotoxin B (SEB) pathogenesis polyposis. The aim this study was to investigate histological and immunologic effects SEB formation polypoid lesions allergic rhinosinusitis murine model. Methods After induction ovalbumin (OVA)-induced rhinosinusitis, OVA with (5 or 500 ng) instilled into cavity mice for...
Light-emitting diodes (LEDs) based on colloidal quantum dots (QDs) have attracted considerable attention due to their potential in applications such as color-saturated displays and white light with high color-rendering index. However, cadmium-based QD-LEDs are strictly regulated industrial because of the toxicity cadmium. As an alternative, InP-based cadmium-free QDs recommended owing wide emission range that is comparable CdSe, environmentally friendly properties when applied QD-LEDs. This...
We report the first synthesis of colloidal CuInTe2, CuInTe2–xSex gradient alloyed quantum dots (QDs) through a simple hot injection method. confirmed composition synthesized QDs to cationic rich phase CuIn1.5Te2.5 and Cu0.23In0.36Te0.19Se0.22 with XPS ICP analysis, we have also found that exhibit greatly improved stability over QDs. The solution-processed solar cell based on exhibited 17.4 mA/cm2 short circuit current density (Jsc), 0.40 V open voltage (Voc), 44.1% fill factor (FF), 3.1%...
Background— Despite the enhanced properties of second-generation drug-eluting stent (DES), its association with neoatherosclerosis has not been sufficiently evaluated. Therefore, we sought to evaluate and compare in DESs first-generation DESs. Methods Results— A total 212 DES-treated patients >50% percent neointimal cross-sectional area stenosis were retrospectively enrolled from Korean multicenter optical coherence tomography (OCT) registry. Within this population, 111 had a DES (40...
Abstract Study Objectives Oral appliance therapy is an increasingly common option for treating obstructive sleep apnea (OSA) in patients who are intolerant to continuous positive airway pressure (CPAP). Clinically applicable tools identify could respond oral limited. Methods Data from three studies (N = 81) were compiled, which included two study nights, on and off treatment. Along with clinical variables, airflow features computed that the average drop during respiratory events (event...
Background In TAILOR-PCI, genotype-guided selection of P2Y12 inhibitors after percutaneous coronary intervention did not significantly reduce the risk ischemic events at 12 months. The Age, Body Mass Index, Chronic Kidney Disease, Diabetes, and Genotyping (ABCD-GENE) score identifies patients with high platelet reactivity on clopidogrel increased events. aim this study was to investigate value ABCD-GENE for tailoring inhibitor intervention. Methods Results a post hoc analysis outcomes were...
Osteoporosis is a widely recognized health problem in postmenopausal women.Osteoporotic fractures reduce independency, limit daily living activities, and increase the mortality rate.Epidemiological studies have demonstrated that low handgrip strength risk factor for functional limitations disabilities, all-cause mortality.We investigated relationship between bone mineral density (BMD) of spine, femur neck, total hip, as well previous fragility 337 healthy Korean women (mean age 59.5 ± 6.8...