A5089285629- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Advanced Optical Imaging Technologies
- Acute Myocardial Infarction Research
- Antiplatelet Therapy and Cardiovascular Diseases
- Chaos-based Image/Signal Encryption
- Cerebrovascular and Carotid Artery Diseases
- Peripheral Artery Disease Management
- Cardiovascular Function and Risk Factors
- Blood Pressure and Hypertension Studies
- Cardiac Valve Diseases and Treatments
- Photonic and Optical Devices
- Coronary Artery Anomalies
- Optical Polarization and Ellipsometry
- Cardiovascular Disease and Adiposity
- Cardiac electrophysiology and arrhythmias
- Advanced Steganography and Watermarking Techniques
- Optical Systems and Laser Technology
- Vascular anomalies and interventions
- Cardiovascular Health and Disease Prevention
- Image Processing Techniques and Applications
- Heart Rate Variability and Autonomic Control
- Heart Failure Treatment and Management
- Hormonal Regulation and Hypertension
- Aortic aneurysm repair treatments
Kyung Hee University
2016-2025
Kyung Hee University Dental Hospital
2009-2023
Kyung Hee University Medical Center
2007-2022
Harvard University
2011-2015
Harbin Medical University
2012-2015
Nara Medical University
2012-2015
Massachusetts General Hospital
2011-2015
Yonsei University
2012-2015
Queen Mary Hospital
2012-2015
University of Hong Kong
2012-2015
Background— Optical coherence tomography (OCT) was recently introduced to optimize percutaneous coronary intervention. However, the exact incidence and significance of poststent OCT findings are unknown. Methods Results— A total 900 lesions treated with 1001 stents in 786 patients who had postprocedure imaging were analyzed evaluate identify predictors for device-oriented clinical end points, including cardiac death, target vessel–related myocardial infarction, lesion revascularization,...
Background— Patients with acute coronary syndrome (ACS) have a higher incidence of recurrent ischemic events. The aim this study was to compare the plaque characteristics nonculprit lesions between ACS and non-ACS patients using optical coherence tomography (OCT) imaging. Methods Results— who had 3-vessel OCT imaging were selected from Massachusetts General Hospital (MGH) Registry. MGH registry is multicenter undergoing OCT. prevalence plaques compared patients. A total 248 found in 104...
Objective— Experimental evidence suggests that exenatide, a glucagon-like peptide 1 receptor analogue, has significant cardiovascular protective effects in various conditions. We examined whether routine use of exenatide at the time primary percutaneous coronary intervention would reduce infarct size patients with ST-segment–elevation myocardial infarction. Approach and Results— Fifty-eight infarction thrombolysis flow 0 were enrolled study randomly assigned to receive either or placebo...
Intravascular imaging-guided percutaneous coronary intervention (PCI) with intravascular ultrasound (IVUS) or optical coherence tomography (OCT) showed superior clinical outcomes compared angiography-guided PCI. However, the comparative effectiveness of OCT-guided and IVUS-guided PCI regarding is unknown.In this prospective, multicenter, open-label, pragmatic trial, we randomly assigned 2008 patients significant artery lesions undergoing in a 1:1 ratio to undergo either an The primary end...
Background— Recent studies have reported development of neoatherosclerosis (NA) inside the stents several years after stent implantation. The aim this study was to determine predictors for NA using optical coherence tomography. Methods and Results— From a total 1080 patients who underwent tomography, we identified 179 in 151 which mean neointimal thickness >100 µm. presence lipid-laden neointima or calcification defined as present study. Patient characteristics, type, time since...
Chronic kidney disease (CKD) promotes the development of atherosclerosis and increases risk cardiovascular disease. The aim present study was to compare coronary plaque characteristics patients with without CKD using optical coherence tomography.We identified 463 nonculprit plaques from 287 Massachusetts General Hospital (MGH) tomography registry. defined as estimated glomerular filtration rate <60 mL/min per 1.73 m(2). A total 402 (250 patients) were in non-CKD group 61 (37 group. Compared...
<h3>Objectives</h3> This study aimed to investigate the role of intraplaque neovascularisation (NV) in culprit lesions and non-culprit unstable angina pectoris (UAP) stable (SAP) using optical coherence tomography (OCT). <h3>Design</h3> was a retrospective study. <h3>Setting</h3> The significance NV for plaques remains unclear. <h3>Participants</h3> A total 356 from 92 UAP patients 25 SAP who underwent OCT imaging were divided into three groups: (92), (203) (61). <h3>Main outcome...
The purpose of this study was to evaluate whether exenatide administration can prevent impairment in endothelium-dependent vasodilatation induced by ischemia-reperfusion (IR) injury and effect is mediated K(ATP) channel opening.In a double-blind, placebo-controlled, crossover design, 20 volunteers were randomly assigned 2 groups: subcutaneous (10 μg) or placebo administration. At 30 minutes after the drug administration, flow-mediated dilatation (FMD) radial artery measured before IR (15...
The pathophysiological basis for the association between metabolic syndrome (MetS) and coronary artery disease is not well understood. We sought to characterize plaques in patients with MetS by using optical coherence tomography.We identified 451 from 171 subjects who underwent tomographic imaging 3 arteries. Subjects were divided into groups: diabetes mellitus (DM, n=77), (n=35), a control group (C group, n=59) without DM or MetS. Optical analysis included presence of lipid-rich plaque,...
Glutathione S-transferase (GST) plays a key role in the detoxification of xenobiotic atherogen generated by smoking. To analyze effect GSTM1/T1 gene polymorphisms on development smoking-related coronary artery disease (CAD), 775 Korean patients who underwent angiography were enrolled. The subjects classified luminal diameter stenosis into group A (>50%), B (20-50%), or C (<20%). GSTM1 and GSTT1 analyzed using multiplex polymerase chain reaction (PCR) for genes CYP1A1 internal control. Of...
Compared with ST elevation myocardial infarction (STEMI), long-term outcomes are known to be worse in patients unstable angina/non-STEMI (UA/NSTEMI), which might related the health status of UA/STEMI. In UA/NSTEMI and STEMI underwent percutaneous coronary intervention (PCI), angina-specific general health-related quality-of-life (HRQOL) was investigated at baseline 30 days after PCI. Patients were older had higher frequencies female, diabetes hypertension. After PCI, both HRQOL scores...
The aim of this study was to demonstrate the efficacy and safety treatment with drug-coated balloon (DCB) in a large real-world population.
Self-monitoring of blood pressure (SMBP) is a reliable method used to assess BP accurately. However, patients do not often know how respond the measured value. We developed mobile application-based feed-back algorithm (SMBP-App) for tailored recommendations. In this study, we aim evaluate whether SMBP-App superior SMBP alone in terms reduction and drug adherence improvement with hypertension.Self-Monitoring Feed-back using APP TReatment UnconTrolled Hypertension (SMART-BP) prospective,...