Amir Lerman

ORCID: 0000-0002-9446-5313
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About
Contact & Profiles
Research Areas
  • Cardiac Imaging and Diagnostics
  • Coronary Interventions and Diagnostics
  • Cardiovascular Health and Disease Prevention
  • Cardiovascular Disease and Adiposity
  • Cerebrovascular and Carotid Artery Diseases
  • Acute Myocardial Infarction Research
  • Renal and Vascular Pathologies
  • Nitric Oxide and Endothelin Effects
  • Blood Pressure and Hypertension Studies
  • Transplantation: Methods and Outcomes
  • Lipoproteins and Cardiovascular Health
  • Atherosclerosis and Cardiovascular Diseases
  • Cardiovascular Function and Risk Factors
  • Cardiac Health and Mental Health
  • Cardiac Valve Diseases and Treatments
  • Tissue Engineering and Regenerative Medicine
  • Aortic aneurysm repair treatments
  • Cardiovascular Issues in Pregnancy
  • Mesenchymal stem cell research
  • Angiogenesis and VEGF in Cancer
  • Electrospun Nanofibers in Biomedical Applications
  • Cardiac Structural Anomalies and Repair
  • Mechanical Circulatory Support Devices
  • Cardiovascular Health and Risk Factors
  • Heart Rate Variability and Autonomic Control

Mayo Clinic
2016-2025

Mayo Clinic in Arizona
2016-2025

WinnMed
2016-2025

Mayo Clinic in Florida
2013-2024

Alfaisal University
2024

Mayo Clinic Health System
2024

Tsuchiura Kyodo General Hospital
2023-2024

Cleveland Clinic
2024

Columbia University Irving Medical Center
2023

Texas Health Dallas
2023

Background —Coronary endothelial dysfunction is characterized by vasoconstrictive response to the endothelium-dependent vasodilator acetylcholine. Although considered an early phase of coronary atherosclerosis, there a paucity information regarding outcome these patients. Thus, this study was designed evaluate patients with mild artery disease on basis their function. Methods and Results —Follow-up obtained in 157 mildly diseased arteries who had undergone vascular reactivity evaluation...

10.1161/01.cir.101.9.948 article EN Circulation 2000-03-07

Takotsubo syndrome (TTS) is a poorly recognized heart disease that was initially regarded as benign condition. Recently, it has been shown TTS may be associated with severe clinical complications including death and its prevalence probably underestimated. Since current guidelines on are lacking, appears timely important to provide an expert consensus statement TTS. The document part I summarizes the state of knowledge presentation characteristics agrees controversies surrounding such...

10.1093/eurheartj/ehy076 article EN cc-by-nc European Heart Journal 2018-04-17

Atherosclerosis is characterized by endothelial injury and the proliferation of arterial smooth-muscle cells. The latter may be a result release growth factors from vessel wall; such include an endothelium-derived vasoconstrictor peptide with mitogenic properties. We tested hypothesis that plasma endothelin concentrations are elevated in persons symptomatic atherosclerosis, independently age.

10.1056/nejm199110033251404 article EN New England Journal of Medicine 1991-10-03

Spontaneous coronary artery dissection (SCAD) is an acute event of uncertain origin. Clinical features and prognosis remain insufficiently characterized.A retrospective single-center cohort study identified 87 patients with angiographically confirmed SCAD. Incidence, clinical characteristics, treatment modalities, in-hospital outcomes, long-term risk SCAD recurrence or major adverse cardiac events were evaluated. Mean age was 42.6 years; 82% female. Extreme exertion at onset more frequent in...

10.1161/circulationaha.112.105718 article EN Circulation 2012-07-17

The clinical expert consensus statement on takotsubo syndrome (TTS) part II focuses the diagnostic workup, outcome, and management. recommendations are based interpretation of limited trial data currently available experience international TTS experts. It summarizes approach, which may facilitate correct timely diagnosis. Furthermore, document covers areas where controversies still exist in risk stratification management TTS. Based provides optimal care such patients for practising physicians.

10.1093/eurheartj/ehy077 article EN cc-by-nc European Heart Journal 2018-04-11

Spontaneous coronary artery dissection (SCAD) is a nonatherosclerotic acute syndrome for which optimal management remains undefined.We performed retrospective study of 189 patients presenting with first SCAD episode. We evaluated outcomes according to initial management: (1) revascularization versus conservative therapy and (2) percutaneous intervention (PCI) stratified by vessel flow at presentation. Demographics were similar in (mean age, 44±9 years; women 92% both groups), but occlusion...

10.1161/circinterventions.114.001659 article EN Circulation Cardiovascular Interventions 2014-11-19

With advances in technology, the physiological assessment of coronary artery disease patients catheterization laboratory has become increasingly important both clinical and research applications, but this evolved without standard nomenclature or techniques data acquisition measurement. Some questions regarding interpretation, application, outcome related to results also remain unanswered. Accordingly, consensus statement was designed provide background evidence about measurements describe...

10.1161/circulationaha.106.177276 article EN Circulation 2006-08-29

BACKGROUND Atrial natriuretic peptide (ANP), brain (BNP), and C-type (CNP) are a family of structurally related peptides that participate in the integrated control renal cardiovascular function. Previous studies suggest functional role for these hormonal cardiorenal regulation congestive heart failure (CHF). METHODS AND RESULTS The present were performed normal subjects (n = 6) patients with mild (New York Heart Association [NYHA] class I to II, n 20) severe (NYHA III IV, CHF by use...

10.1161/01.cir.88.3.1004 article EN Circulation 1993-09-01
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