- Animal Nutrition and Physiology
- Engineering Applied Research
- Animal Behavior and Welfare Studies
- Cultural and Historical Studies
- Reproductive Biology and Fertility
- Korean Urban and Social Studies
- Diverse Topics in Contemporary Research
- Meat and Animal Product Quality
- Animal Genetics and Reproduction
- Agriculture, Soil, Plant Science
- Gut microbiota and health
- Sperm and Testicular Function
- Diverse Approaches in Healthcare and Education Studies
- Energy and Environmental Systems
- Pesticide Residue Analysis and Safety
- Food Quality and Safety Studies
- Genetic and phenotypic traits in livestock
- Insect and Pesticide Research
- Consumer Perception and Purchasing Behavior
- Mycotoxins in Agriculture and Food
- CRISPR and Genetic Engineering
- Adipose Tissue and Metabolism
- Reproductive Physiology in Livestock
- Urban and spatial planning
- Pluripotent Stem Cells Research
Stanford University
2014-2025
North Carolina State University
2016-2025
Seoul National University Hospital
2017-2025
Seoul National University
2001-2025
National Institute of Animal Science
2015-2025
Rural Development Administration
2013-2025
Komipharm International (South Korea)
2018-2025
Asan Medical Center
2009-2025
University of Ulsan
2002-2025
Ulsan College
2014-2025
Type 2 iodothyronine deiodinase (D2) is a selenoenzyme, the product of recently cloned cAMP-dependent Dio2 gene, which increases 10- to 50-fold during cold stress only in brown adipose tissue (BAT). Here we report that despite normal plasma 3,5,3'-triiodothyronine (T3) concentration, cold-exposed mice with targeted disruption gene (Dio2(-/-)) become hypothermic due impaired BAT thermogenesis and survive by compensatory shivering consequent acute weight loss. This occurs basal mitochondrial...
This study evaluated the effect of fermentation on nutritional quality food-grade soybeans and feedgrade soybean meals. Soybeans meals were fermented by Aspergillus oryzae GB-107 in a bed-packed solid fermentor for 48 hours. After fermentation, their nutrient contents as well trypsin inhibitor measured compared with those raw Proteins extracted from non-fermented meals, peptide characteristics after electrophoresis. Fermented contained 10% more (P < .05) crude protein than The essential...
Type 2 iodothyronine deiodinase (D2) is a selenoenzyme, the product of recently cloned cAMP-dependent Dio2 gene, which increases 10- to 50-fold during cold stress only in brown adipose tissue (BAT). Here we report that despite normal plasma 3,5,3′-triiodothyronine (T3) concentration, cold-exposed mice with targeted disruption gene (Dio2–/–) become hypothermic due impaired BAT thermogenesis and survive by compensatory shivering consequent acute weight loss. This occurs basal mitochondrial...
Abstract The gut microbiota plays an important role in nutrient digestibility animals. To examine changes the pig across growth stages and its effects on digestion, population pigs at 28 days (before weaning) 60, 90 150 of age was assessed by 16S rDNA gene sequencing. apparent crude fiber (CF), neutral detergent (NDF), acid (ADF), protein (CP) ether extract (EE) also these pigs. A total 19,875 operational taxonomic units (OTUs) were identified from all samples. Both bacterial abundance...
Arginine is a common substrate for the synthesis of nitric oxide and polyamines that are crucial placental angiogenesis growth in mammals. This study was conducted to test hypothesis dietary l-arginine supplementation may improve reproductive performance pregnant gilts. Fifty-two gilts with body weight (BW) 166.3 ± 1.8 kg were housed individually gestation crates. At d 30 gestation, assigned randomly corn-soybean-based diets supplemented 1.0% l-arginine-HCl or 1.7% l-alanine (isonitrogenous...
A total of 216 weaning pigs were used in 2 experiments to determine the effects dietary supplementation yeast culture (YC) at different dose levels on growth performance, nutrient digestibility, intestinal morphology, microflora, and immune response weanling whether YC can be a candidate replace antibiotic promoters (AGP). In Exp. 1, 192 (7.5 +/- 0.2 kg BW) weaned 28 d age randomly allotted 6 treatments: 1) control (without AGP or YC); 2) (chlortetracycline, 80 mg/kg); 3) 2.5 g/kg (Diamond V...
To identify the specific locations of type 2 deiodinase (D2) messenger RNA (mRNA) in hypothalamus and pituitary gland determine its regulation by thyroid hormone, we performed situ hybridization histochemistry, Northern analysis, quantitative RT-PCR euthyroid, hypothyroid, hyperthyroid rats. By silver grains were concentrated over ependymal cells lining floor infralateral walls third ventricle extending from rostral tip median eminence (ME) to infundibular recess, surrounding blood vessels...
Big mitogen-activated protein kinase 1 (BMK1), also known as ERK5, is a member of the MAPK family. Genetic ablation BMK1 in mice leads to embryonic lethality, precluding exploration pathophysiological roles adult mice. We generated conditional mutation which disruption gene under control inducible Mx1-Cre transgene. Ablation led lethality within 2–4 weeks after induction Cre recombinase. Physiological analysis showed that blood vessels became abnormally leaky deletion gene. Histological...
Three hundred twenty fetuses were obtained from 33 pregnant gilts (Camborough-22, Pig Improvement Co.) to determine rates of nutrient deposition in fetal tissues and estimate requirements for growth. Pregnant fed an equal amount a gestation diet (2.0 kg/d; as-fed basis), slaughtered at d 0, 45, 60, 75, 90, 102, or 110 (n = 3 6 per day). Fetuses dissected into carcass individual (including gastrointestinal tract, liver, lung, heart, kidney, spleen [≥d 75]), partial placental collection was...
Big mitogen-activated protein kinase 1 (BMK1), also known as ERK5, is a member of the MAPK family. Genetic ablation BMK1 in mice leads to embryonic lethality, precluding exploration pathophysiological roles adult mice. We generated conditional mutation which disruption gene under control inducible Mx1-Cre transgene. Ablation led lethality within 2–4 weeks after induction Cre recombinase. Physiological analysis showed that blood vessels became abnormally leaky deletion gene. Histological...
Pigs suffer up to 50% embryonic and fetal loss during gestation exhibit the most severe naturally occurring intrauterine growth retardation among livestock species. Placental insufficiency is a major factor contributing suboptimal reproductive performance reduced birth weights of pigs. Enhancement placental function through nutritional management offers an effective solution improving survival growth. We discovered unusual abundance arginine family AA in porcine allantoic fluid (a reservoir...
The growth and health of the fetus neonate are directly influenced by nutritional physiological status sows.Sows often under catabolic conditions due to restrict feeding program during pregnancy low voluntary feed intake lactation.The current program, which aims at controlling energy gestation, results in an inadequate supply dietary protein for fetal mammary gland growth.Low lactation also causes massive maternal tissue mobilization.Provision amino acids fatty with specific functions may...