A5054099895- Nutrition and Health in Aging
- Adipokines, Inflammation, and Metabolic Diseases
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Diabetes Management and Education
- Adipose Tissue and Metabolism
- Bone Metabolism and Diseases
- Bone health and osteoporosis research
- Diabetes and associated disorders
- Pituitary Gland Disorders and Treatments
- Diet and metabolism studies
- Adrenal Hormones and Disorders
- Growth Hormone and Insulin-like Growth Factors
- Frailty in Older Adults
- Bone health and treatments
- Metabolism, Diabetes, and Cancer
- Diabetes Management and Research
- Thyroid Disorders and Treatments
- Biomarkers in Disease Mechanisms
- Diet, Metabolism, and Disease
- Vitamin D Research Studies
- Diabetes Treatment and Management
- Advanced Glycation End Products research
- Health and Wellbeing Research
- Cardiovascular Function and Risk Factors
- Obesity and Health Practices
Asan Medical Center
2024
Tallaght University Hospital
2024
University of Ulsan
2024
Ulsan College
2024
Seoul National University Bundang Hospital
2023
CM Hospital
2018-2019
Hallym University Kangnam Sacred Heart Hospital
2013-2019
Hallym University Medical Center
2010-2019
Hallym University
2009-2018
British Geriatrics Society
2018
Summary Objective Body weight is a significant predictor of bone mass. Hormonal factors such as sex hormones, insulin, leptin and adiponectin are thought to play role in the mechanisms controlling association body fat mass with However, contradictory results have been reported for between serum adipocytokines mineral density (BMD). We therefore examined whether adipocytokine ghrelin levels, markers metabolism, associated BMD male adults. Patients measurements For 80 adults (average age 54·5...
We studied the prevalence and trend of obesity metabolic syndrome in Korean adults aged at least 20 years using National Health Examination Nutrition Survey data from 1998 2001. The body mass index (BMI) > or = 25 kg m(-2) among 2001 was 32.9% men 27.4% women, number with BMI has increased markedly since 1998. A significant positive association between socioeconomic status found men, whereas a negative identified women. rates waist circumference (WC) 90 cm WC 85 women were 23.4% 23.1%...
There are few studies that have used audiometric testing to gauge the demographic characteristics and associated risk factors for hearing loss at national-level. Here, we investigated weighted prevalence of impairment in 16,040 Korean adult population. Subjects completed test laboratory examination as part data from The 2010–2012 Korea National Health Nutrition Examination Survey (KNHANES). In our respective study, overall (n = 33,762,584) mild among population was 20.5% (95% clearance [CI],...
Epidemiological studies have suggested an association between Hashimoto thyroiditis (HT) and papillary thyroid cancer (PTC) development. Other studies, however, reported a protective role of HT against PTC progression. Through this updated meta-analysis, we aimed to clarify the effects on progression PTC.We searched citation databases, including PubMed Embase, for relevant from inception September 2017. From these calculated pooled odds ratios (ORs) clinicopathologic features relative risk...
Background/Aims Recent epidemiological studies revealed a striking inverse relationship between vitamin D levels, glucose intolerance/insulin resistance (IR), and cardiovascular disease. However, few interventional have evaluated the effect of supplementation on risk, such as IR arterial stiffness, in diabetes. We investigated role risk type 2 diabetes patients, including metabolic parameters, IR, stiffness. Methods enrolled patients who were taking antidiabetic medications or managed their...
Epidemiologic studies have shown that low vitamin D levels are associated with reduced insulin sensitivity and increased risk of developing type 2 diabetes mellitus (T2DM). However, there is little evidence supplementation improves glucose intolerance. We evaluated the glucose-lowering effect in Korean T2DM subjects. enrolled 158 patients who had stable glycemic control [hemoglobin A1c (HbA1c) <8.5%] less than 20 ng/mL. The participants were randomized into two groups: Placebo (100 mg daily...
Summary Objective Osteoporosis is a growing health problem in males as well females. Sex hormones and insulin‐like growth factor‐I (IGF‐I) have been shown to be the major determinants male bone metabolism. Osteoprotegerin (OPG) recently identified cytokine that acts decoy receptor for activator of NF‐κB ligand (RANKL). OPG RANKL important regulators osteoclastogenesis. However, relationship between OPG‐RANKL system status human populations are unclear. Thus, aim this study was investigate...
We designed a system for diabetes patients treated with glargine, long-acting insulin, to make an automatic adjustment of insulin dose based on glucose level data and provide the needed by using short message service (SMS). also compared who used our received conventional titration scheme.Included were 100 type 2 whose blood was suboptimally controlled their previous antidiabetes treatment. Each participant assigned either intervention or control group, each 50 patients, adaptive...
Sarcopenia, a common clinical syndrome in older adults, is defined as decreased muscle mass, strength, and physical performance. Since sarcopenia associated with the incidence of functional decline, falls, even mortality researchers health care providers have been keen to accumulate evidence advocate screening prevention progression adults. The factors that may accelerate loss mass function include chronic diseases, inactivity, deficiency appropriate nutritional support. Among these, support...
The influence of the novel heat shock protein 90 (hsp90) inhibitor NVP-AUY922 (AUY922) on anaplastic thyroid carcinoma (ATC) cells has not been investigated. effect AUY922 alone or in combination with histone deacetylase PXD101 survival ATC was evaluated. In cells, AUY922, compared 17-allylamino-17-demethoxygeldanamycin, herbimycin A and radicicol, potently lead to growth inhibition cell death cleavage caspase-3 poly (ADP-ribose) polymerase (PARP) concomitant changes expression hsp90 client...
PURPOSE Chemerin has been suggested to be linked insulin resistance and type 2 diabetes mellitus (T2DM). However, the relationship between visceral adiposity chemerin levels remains unclear in subjects with T2DM. In this study, we investigated serum adiposity. MATERIALS AND METHODS This study included 102 newly diagnosed The relationships clinical biochemical parameters were examined. Multiple linear regression analysis was performed determine predictable factors of levels. RESULTS Serum...
Purpose: Proliferation of vascular smooth muscle cells (VSMCs) plays a crucial role in atherosclerosis.Rutin is major representative the flavonol subclass flavonoids and has various pharmacological activities.Currently, data are lacking regarding its effects on VSMC proliferation induced by intermittent hyperglycemia.Here, we demonstrate rutin migration according to fluctuating glucose levels.Materials Methods: Primary cultures male Otsuka Long-Evans Tokushima Fatty (OLETF) rat VSMCs were...
This study aimed to explore the relation of immunoglobulin G4 (IgG4) clinical and laboratory characteristics patients newly diagnosed with Graves' disease (GD) without or ophthalmopathy (GO) analyze association IgG4 development grade GO in GD patients.Sixty-four 64 sex- age-matched euthyroid subjects were enrolled. Serum levels thyroid hormones, autoantibodies, G (IgG), measured, ophthalmological ultrasonographical evaluation was performed.In compared subjects, autoantibodies as well...
This study aimed to identify the gender-specific characteristics of surrogate measures insulin resistance and establish valid cut-off values for metabolic abnormalities in a representative sample Korea.Data were collected from datasets Korean National Health Nutrition Examination Survey between 2007 2010. The total number eligible participants was 10,997. We used three resistance: homeostasis model assessment-insulin (HOMA-IR), McAuley index, triglyceride glucose (TyG) index. estimated...
Summary objective Osteoprotegerin (OPG) is a recently identified cytokine that acts as decoy receptor for the RANK ligand. Moreover, OPG has been shown to be an important inhibitor of osteoclastogenesis in animal models. However, relationship between circulating levels and female bone status human populations unclear. In this study we undertook investigate mineral metabolism healthy women. patients measurements Our subjects were 287 women aged 37–73 years (mean age 51·5 years). The serum...