A5100377984- Allergic Rhinitis and Sensitization
- Sinusitis and nasal conditions
- Asthma and respiratory diseases
- Obstructive Sleep Apnea Research
- Nasal Surgery and Airway Studies
- Neuroscience of respiration and sleep
- Olfactory and Sensory Function Studies
- Tracheal and airway disorders
- Silk-based biomaterials and applications
- EEG and Brain-Computer Interfaces
- Helicobacter pylori-related gastroenterology studies
- Vestibular and auditory disorders
- Ear Surgery and Otitis Media
- Head and Neck Surgical Oncology
- Orthopedic Surgery and Rehabilitation
- Dysphagia Assessment and Management
- Dermatology and Skin Diseases
- IL-33, ST2, and ILC Pathways
- Shoulder Injury and Treatment
- Sleep and Wakefulness Research
- Hearing, Cochlea, Tinnitus, Genetics
- Electrospun Nanofibers in Biomedical Applications
- SARS-CoV-2 and COVID-19 Research
- Parkinson's Disease Mechanisms and Treatments
- High-Velocity Impact and Material Behavior
Korea Gas Corporation (South Korea)
2002-2025
Hanyang University
2005-2025
Anyang University
2025
Food & Nutrition
2025
Konkuk University
2013-2025
National IT industry Promotion Agency
2022-2025
Hallym University
2015-2024
Chuncheon Sacred Heart Hospital
2015-2024
Ajou University
2004-2024
Daegu-Gyeongbuk Medical Innovation Foundation
2017-2024
2,3,7,8-Tetrachlorodibenzo-<i>p</i>-dioxin (TCDD) is a widespread environmental pollutant with many toxic effects, including endocrine disruption, reproductive dysfunction, immunotoxicity, liver damage, and cancer. These are mediated by TCDD binding to activating the aryl hydrocarbon receptor (AhR), basic helix-loop-helix transcription factor. In this regard, targeting AhR using novel small molecule inhibitors an attractive strategy for development of potential preventive agents. study,...
Psychological factors and subtle histopathological changes have been implicated in irritable bowel syndrome (IBS). The aims of the present study were to investigate whether numbers enterochromaffin (EC) cells, mast lamina propria T lymphocytes are altered IBS, evaluate relationship such alterations with psychological factors.Forty-two consecutive IBS patients (M : F = 17:25, mean age 48 years) fulfilling Rome III criteria twelve asymptomatic healthy controls underwent rectal biopsy....
<h3>Rationale</h3> Interleukin (IL)-33, a new member of the IL-1 family, is constitutively expressed in epithelial tissues and lymphoid organs plays an important role pathogenesis allergic disease. However, IL-33 chronic rhinosinusitis with nasal polyps (CRSwNP) remains unclear. <h3>Objective</h3> To investigate pathophysiology CRSwNP. <h3>Methods</h3> We investigated expression its cellular origins (NPs) human subjects by immunohistochemistry (IHC), quantitative reverse transcription PCR...
ABSTRACT Integrity management of pipeline networks is crucial for preemptive maintenance and preventing accidents. In this study, various methods improving the localization accuracy offline navigation algorithm an intelligent inspection gauge (PIG) in‐line (ILI) robotic system are proposed. The digital mapping utilizes extended Kalman filter (EKF) with a Rauch–Tung–Striebel (RTS) smoother. Two ILI tools introduced—magnetic flux leakage (MFL) PIG, which typical PIG detecting corrosion defects...
In this study, a surface treatment process was introduced into the conventional dispersion for preparing wet-laid nonwoven fabrics to improve their properties, using recycled carbon fibers (rCFs). The binder solution replaced with containing different amounts of silane, and changes in fiber properties prepared were examined after addition modified rCFs polypropylene. FE-SEM analysis confirmed that silane layer formed on rCF due formation siloxane network. FT-IR XPS analyses further presence...
The estimation of robot pose and pipe diameter is an essential task for reliable in-line inspection (ILI) operations the accurate assessment pipeline attributes. This paper addresses problem natural gas pipelines based on 3D time-of-flight (ToF) sensors. To tackle this challenge, we model as a non-linear least-squares optimization that fits ToF sensor measurements in its local coordinates to elliptic cylindrical inner surface. We identify prove canonical ellipse-based method (C-EPD), which...
Abstract Purpose: To survive in an ischemic microenvironment with a lower extracellular pH, ability to up-regulate proton extrusion is critical for cancer cell survival. Gastric H+/K+-ATPase exchanges luminal K+ cytoplasmic H+ and the enzyme primarily responsible gastric acidification. On basis of fact that blocking clearance acidic metabolites are known induce death, we hypothesized pantoprazole (PPZ), one inhibitors used frequently treat acid-related diseases, could inhibit growth tumor...
A series of zirconium-doped nano-titania (Zr/TiO2) with various amounts Zr were prepared by sol–gel method using titanium(IV) isopropoxide and zirconium nitrate as precursors. Zr/TiO2 samples characterized X-ray diffraction (XRD), surface area–pore volume measurements, infrared (FTIR) spectroscopy, UV–vis-diffuse reflectance spectroscopy (UV–vis-DRS), photoelectron (XPS), Raman thermogravimetric (TG) analysis, transmission electron microscopy (TEM) techniques. XRD data spectra indicated that...
Porous silk scaffolds, which are considered to be natural polymers, cannot used alone because they have a long degradation rate, makes it difficult for them replaced by the surrounding tissue. Scaffolds composed of synthetic such as PLGA, short lack hydrophilicity and their release toxic by-products use. The present investigations aimed study hybrid scaffolds fabricated from hydroxyapatite nanoparticles (Hap NPs) optimized bone tissue engineering. results variable-pressure field emission...
Studies comparing surgical results of rhinoplasty using autologous costal cartilage (ACC) and irradiated homologous (IHCC) are rare. To compare the clinical major augmentation ACC vs IHCC analyze histologic properties both types cartilage. A retrospective study was conducted among patients who had undergone rhinoseptoplasty or from January 1, 2009, to December 31, 2014. Patients were followed up for more than 1 year after surgery characteristics compared. The details procedures...
<h3>Importance</h3> Chronic rhinosinusitis (CRS) is associated with a decreased quality of life, affecting physical and emotional aspects daily function, the latter which could manifest as depression anxiety. <h3>Objective</h3> To evaluate risk anxiety in CRS, depending on CRS phenotype (CRS without nasal polyps [CRSsNP] [CRSwNP]). <h3>Design, Setting, Participants</h3> This retrospective nationwide cohort study used population-based insurance data (consisting from approximately 1 million...
Endotype in chronic rhinosinusitis (CRS) has been established the last decade. However, exact immunologic profile of CRS still controversy because it a considerable heterogeneity. Therefore, we investigated various inflammatory mediators according to different nasal tissues and compared them within same subject.We collected uncinate process mucosa (UP) polyp (NP) from controls, without NP (CRSsNP) with (CRSwNP). Expression levels 28 including T helper (Th) 1, Th2, Th17, proinflammatory...
Abstract While full-night polysomnography is the gold standard for diagnosis of obstructive sleep apnea, its limitations include a high cost and first-night effects. This study developed an algorithm detection respiratory events based on impulse-radio ultra-wideband radar verified feasibility apnea. A total 94 subjects were enrolled in this (23 controls 24, 14, 33 with mild, moderate, severe respectively). Abnormal breathing detected by was defined as drop peak signal ≥30% from that...
<h3>Importance</h3> Burning mouth syndrome is a chronic oral pain disorder that characterized by generalized or localized burning sensation without the presence of any specific mucosal lesions. It remains unclear, however, whether associated with development psychoneurological conditions among patients syndrome. <h3>Objective</h3> To evaluate risk developing conditions, including depression, anxiety, dementia, and Parkinson disease, in <h3>Design, Setting, Participants</h3> This...
Abstract To maximize the impact of precision medicine approaches, it is critical to identify genetic variants underlying disease and accurately quantify their functional effects. A gene exemplifying challenge variant interpretation von Hippel–Lindautumor suppressor ( VHL ). encodes an E3 ubiquitin ligase that regulates cellular response hypoxia. Germline pathogenic in predispose patients tumors including clear cell renal carcinoma (ccRCC) pheochromocytoma, somatic mutations are frequently...
Parkinson's disease (PD) is a complex neurodegenerative disorder with an unclear etiology. Despite significant research efforts, developing disease-modifying treatments for PD remains major unmet medical need. Notably, drug repositioning becoming increasingly attractive direction in discovery, and computational approaches offer relatively quick resource-saving method identifying testable hypotheses that promote repositioning. We used artificial intelligence (AI)-based strategy to screen...
<i>Background/Aims:</i> Atypical manifestations of gastroesophageal reflux disease (GERD) are diverse. We aimed to determine whether pepsin detection in the sputum/saliva could be useful for diagnosing GERD patients with clinically suspected atypical symptoms. <i>Methods:</i> Patients symptoms provided collected before bedtime, at time those symptoms, and after awakening measurement by Western blot analysis. All subjects received 24-hour esophageal pH monitoring, then...
The performance of vanadia-doped zirconia-pillared clay (V/Zr-PILC) for the selective catalytic oxidation H2S was investigated in this study. A series zirconia pillared clays (V/Zr-PILCs) with various amounts vanadia were prepared and characterized using X-ray diffraction (XRD), surface area-pore volume measurements, chemical analysis, infrared (FTIR) spectroscopy, UV–vis-diffuse reflectance spectroscopy (UV–vis-DRS), photoelectron (XPS), thermogravimetric (TG) analysis. V/Zr-PILCs showed...