A5101734356- Education and Learning Interventions
- Adipokines, Inflammation, and Metabolic Diseases
- Bone Metabolism and Diseases
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Breast Cancer Treatment Studies
- Diet and metabolism studies
- Educational Research and Pedagogy
- Adipose Tissue and Metabolism
- Education, Safety, and Science Studies
- Bone health and osteoporosis research
- Metabolism, Diabetes, and Cancer
- Cardiovascular Disease and Adiposity
- Diet, Metabolism, and Disease
- Bone health and treatments
- Educational Systems and Policies
- Liver Disease Diagnosis and Treatment
- Peroxisome Proliferator-Activated Receptors
- Nutrition and Health in Aging
- Diabetes Management and Research
- Thyroid Cancer Diagnosis and Treatment
- Nutrition, Health and Food Behavior
- Astrophysics and Cosmic Phenomena
- Regulation of Appetite and Obesity
- Topological Materials and Phenomena
- Psychosocial Factors Impacting Youth
Chosun University
2025
Samsung Medical Center
2007-2024
Konyang University
2024
Sungkyunkwan University
2009-2022
Korea Advanced Institute of Science and Technology
2022
University of Cambridge
2022
Osaka City University
2021
Institute for Basic Science
2021
Samsung (South Korea)
2004-2019
Jeonbuk National University
2015
The effects of exendin-4 on Sirt1 expression as a mechanism reducing fatty liver have not been previously reported. Therefore, we investigated whether the beneficial treatment are mediated via in high-fat (HF) diet-induced obese C57BL/6J mice and related cell culture models. Exendin-4 decreased body weight, serum free acid (FA), triglyceride levels HF-induced mice. Histological analysis showed that reversed hepatic accumulation lipids inflammation. increased mRNA protein its downstream...
Recent studies suggest an association of vitamin D with obesity, diabetes and cardiovascular diseases. We analyzed the serum level assessed by 25-hydroxyvitamin D3 {25(OH)D3 } nonalcoholic fatty liver disease (NAFLD) in apparently healthy men. performed a cross-sectional study 6,567 Korean men who participated health screening program, evaluating 25(OH)D3 levels risk NAFLD abdominal ultrasonogram. Of participants, 43.6% had 21.1% metabolic syndrome. Age, calcium, aspartate aminotransferase...
We investigated the relationships of adiponectin/leptin (A/L) ratio with cardiovascular risk factors, insulin resistance index, and metabolic syndrome (MS) in apparently healthy Korean male adults.Sixty-eight subjects were enrolled among participants an annual health check-up program (mean age, 55.1 years). Percent body fat (%) was measured using a bioelectric impedance analyzer. Serum leptin level via radioimmunoassay, adiponectin enzyme-linked immunosorbent assay. Homeostasis model...
Diffusion models excel in generative tasks, but aligning them with specific objectives while maintaining their versatility remains challenging. Existing fine-tuning methods often suffer from reward over-optimization, approximate guidance approaches fail to optimize target rewards effectively. Addressing these limitations, we propose a training-free sampling method based on Sequential Monte Carlo (SMC) sample the reward-aligned distribution. Our approach, tailored for diffusion and...
Objectives Cardiovascular disease (CVD) is a major cause of death in Korea, and studies have reported that asthma can negative impact on CVD. This study aimed to identify the association between CVD, including current status, treatment duration Korean adults.
The relative importance of sensory air pollution, thermal load and noise was studied under controlled conditions in two identical environmental chambers. In one chamber subjects were exposed to various levels either or poor indoor quality. For each condition tested this chamber, the a number an adjacent with neutral good quality order determine level causing same degree discomfort. A total 68 comparisons chambers made by group 16 after one-minute exposure chamber. operative temperature range...
The emerging paradigm of Web services opens a new way application design and development to quickly develop deploy applications by integrating independently published components conduct business transactions. As research aiming at facilitating integration verification, WS-Net is an executable architectural description language incorporating the semantics colored Petri-net with style understandability object-oriented concepts. describes each component in three layers: interface net declares...
OPG (osteoprotegerin) is an inhibitor of osteoclastogenesis and recent work suggests it has a role in atherosclerosis. Therefore we measured serum levels patients with coronary artery disease, compared the among different groups according to number stenotic vessels determined whether there was any correlation aortic calcification, LV (left ventricular) mass index CRP (C-reactive protein) levels. Subjects (n=100; mean age, 57 years) who underwent angiograms were enrolled. Blood pressure, body...
Abstract Background Several studies have suggested a cancer risk reduction in statin users although the evidence remains weak for stomach cancer. The purpose of this study was to use an exact-matching case–control design examine gastric associated with statins cohort patients diabetes. Methods Cases were defined as incident identified by International Classification Diseases 16.0 ~ 16.9 recorded at Samsung Medical Center database during period 1999 2008, least 6 months after entry date...
Patients with amnestic mild cognitive impairment (aMCI) have an increased risk of dementia. However, conversion rate varies. Therefore, predicting the dementia in these patients is important.We aimed to develop a nomogram predict aMCI subjects using neuropsychological profiles.A total 338 from two hospital-based cohorts were used analysis. All classified into 1) verbal, visual, or both, 2) early late, and 3) single multiple-domain according modality, severity memory dysfunction, multiplicity...
It remains to be elucidated whether exposure air pollutants aggravates atopic dermatitis (AD). This study aimed evaluate the effects of formaldehyde for 1 h and 2 on skin barrier function in both control AD groups. In 41 patients with 34 healthy children, a provocation test was performed which two different areas normal‐appearing forearm were stimulated airborne at 500 μg m−3 or placebo h. We measured transepidermal water loss (TEWL) pH, calculated percentage change from baseline. Exposure...
Adiponectin, an adipocyte-secreted protein, is known to have anti-atherogenic, anti-inflammatory and anti-diabetic properties its serum levels are decreased in obesity, type 2 diabetes, coronary artery disease. Several studies been performed investigate the association of genetic variations adiponectin with insulin resistance, but few were Therefore we examined associations between two single nucleotide polymorphisms (SNPs), +45T>G +276G>T gene, diseases (CAD). One hundred fifty six subjects...
The emerging paradigm of Web services opens a new way application design and development to quickly develop deploy applications by integrating independently published components conduct business transactions. As research aiming at facilitating integration verification, WS-Net is an executable architectural description language incorporating the semantics colored Petri-net with style understandability object-oriented concepts. describes each component in three layers: interface net declares...
Background and Objectives To present treatment outcomes prognostic factors for surgical management of locally advanced differentiated thyroid cancer (DTC).Retrospective review 70 patients in a single, tertiary referral institution was done. Clinical pathology characteristics were analyzed to investigate prognosticators, based on primary endpoints; locoregional recurrence alone (LRR), total (LRR or distant metastasis (DM)), recurrence-free survival.Recurrent laryngeal nerve (n = 31) trachea...