- Cervical Cancer and HPV Research
- Molecular Biology Techniques and Applications
- Liver Disease Diagnosis and Treatment
- Hepatitis B Virus Studies
- Genital Health and Disease
- Diabetes Management and Research
- Chronic Kidney Disease and Diabetes
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Erythrocyte Function and Pathophysiology
- Vitamin D Research Studies
- Ovarian function and disorders
- Renal Diseases and Glomerulopathies
- Adipokines, Inflammation, and Metabolic Diseases
- Cytomegalovirus and herpesvirus research
- Bone health and osteoporosis research
- Biotin and Related Studies
- Bone health and treatments
- Urinary Tract Infections Management
- Circadian rhythm and melatonin
- Dialysis and Renal Disease Management
- Vitamin C and Antioxidants Research
- Regulation of Appetite and Obesity
- Acute Ischemic Stroke Management
- Reproductive tract infections research
- Mycobacterium research and diagnosis
Sungkyunkwan University
2016-2025
Kangbuk Samsung Hospital
2016-2025
Hudson Institute
2022
Ministry of Health and Welfare
2017
Samsung Medical Center
2004-2015
Background & AimsAlthough coronavirus disease 2019 (COVID-19) is characterized by fever and respiratory symptoms, some patients have no or mild symptoms. Severe acute syndrome-coronavirus (SARS-CoV-2) has been detected in feces of patients. We investigated gastrointestinal symptoms shedding virus into with asymptomatic COVID-19.MethodsWe collected data from 46 (median age, 26 y; 46% men) COVID-19 (without pneumonia) prolonged SARS-CoV-2, quarantined April 4, 2020, through 24, Korea....
Assessment of Helicobacter pylori (H. pylori) clarithromycin resistance has rarely been performed routinely despite an increasing rate. Our aim was to develop and evaluate the use dual-priming oligonucleotide (DPO)-based multiplex polymerase chain reaction (PCR) detect point mutations in 23S rRNA gene responsible for H. pylori.Gastric biopsy specimens from 212 untreated patients with dyspepsia were examined by culture, histology, DPO-based PCR. A disk diffusion test E-test used performing...
Several recent prospective studies have reported that obesity is associated with an increased risk for chronic kidney disease (CKD), but it unknown whether weight gain increases the CKD if one remains within "normal" category of body mass index (BMI). We prospectively followed a cohort 8792 healthy men who had no known factors and participated in comprehensive health evaluation program at large worksite. During 35,927 person-years follow-up, 427 new incident cases (estimated GFR <64 ml/min...
The aim of the present study was to compare associations anti-Müllerian hormone (AMH) with clinical or biochemical characteristics between women and without polycystic ovary syndrome (PCOS). We also explored optimal cutoff point AMH diagnose PCOS. A cross-sectional performed in 87 diagnosed PCOS 53 healthy control subjects. Body mass index (BMI), indices insulin resistance, metabolic syndrome-related variables, reproductive hormones serum were measured all conducted receiver operating...
Omentin-1 is a novel adipokine that increases insulin sensitivity and expressed in visceral adipose tissue. The aim of this study was to determine the metabolic parameters influence plasma omentin-1 levels women with polycystic ovary syndrome (PCOS).A cross-sectional performed 87 PCOS 53 body mass index (BMI)-matched healthy controls including 39 non-obese, normal-weight (NW) normal glucose tolerance (NGT) 44 BMI- homeostasis model assessment (HOMA)-matched controls. Indices sensitivity,...
OPG (osteoprotegerin) is an inhibitor of osteoclastogenesis and recent work suggests it has a role in atherosclerosis. Therefore we measured serum levels patients with coronary artery disease, compared the among different groups according to number stenotic vessels determined whether there was any correlation aortic calcification, LV (left ventricular) mass index CRP (C-reactive protein) levels. Subjects (n=100; mean age, 57 years) who underwent angiograms were enrolled. Blood pressure, body...
<b><i>Background:</i></b> Decreased glomerular filtration rate (GFR) can increase the risk of bleeding tendency and hemorrhagic stroke. However, relationship between levels GFR transformation (HT) after acute ischemic stroke is largely unknown. The aim this study was to assess whether level associated with HT in <b><i>Methods:</i></b> We reviewed 770 consecutive patients within 7 days from September 2007 February 2012 a prospective registry...
Background The effects of age, gender, and seasonal variation on human levels 25‐hydroxyvitamin D (25(OH)D) are not well understood. In this study, we aimed to investigate 25(OH)D status according these factors in a Korean population. Methods A total 303,943 serum were measured using an electrochemiluminescence immunoassay between October 2011 May 2014. Potential participants ineligible for the study if they had significant renal, hepatic, or thyroid dysfunction, as any major ongoing disease...
Binge eating occurs more frequently in women than men, and is known to be related psychological factors such as stress, depression, anxiety. This study examined the relationship between binge trait anxiety, perceived stress Korean adolescents.Four hundred girls (aged 17-18 years) from two high schools located Seoul completed self-report questionnaires. In total, 327 participants returned reliable responses, were included final study. was measured using Bulimic Inventory Test Edinburgh. The...
Introduction Non-alcoholic fatty liver disease (NAFLD) is the most prevalent cause of chronic worldwide. Accurate assessment fibrosis essential for prognosis and management NAFLD. Mean platelet volume (MPV), an index activation, has been associated with in various diseases; however, its role NAFLD remains uncertain. Methods This study analyzed data from 70,830 patients who underwent a comprehensive health examination between 2015 2019. Patients were stratified into three groups based on...
Objective The pathophysiology of social anxiety disorder (SAD) is not yet well understood, but previous research has suggested that oxytocin associated with behavior and may play a role in human states anxiety-related traits. aim this study was to investigate the possible relationship between symptoms plasma levels. Methods Twenty-three male patients SAD 28 healthy controls participated study. All participants were assessed using Mini International Neuropsychiatric Interview (MINI) Liebowitz...
High-risk human papillomavirus (HR-HPV) infection is a leading cause of cervical cancer, which (HPV)-16 and HPV-18 account for about 70% cases. Since HPV common, it important to focus on the genotypes that pose highest risk effective cancer screening. In this study, we evaluated clinical usefulness HPV-16/HPV-18 genotyping
Background The associations of vitamin D deficiency with many nonskeletal diseases are still being discovered. We evaluated the use an automated immunoassay to measure serum total (25‐OH) and assessed status in a Korean adult population. Methods compared Elecsys Vitamin Total Assay (Roche Diagnostics) liquid chromatography‐tandem mass spectrometry (LC‐MS/MS) using 300 samples. imprecision was calculated three levels quality control materials also investigated data for 70,762 cases who had...