A5062402889- Liver Disease Diagnosis and Treatment
- Sleep and related disorders
- Cardiovascular Function and Risk Factors
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Nutrition and Health in Aging
- Diet, Metabolism, and Disease
- Colorectal Cancer Screening and Detection
- Sleep and Work-Related Fatigue
- Obesity, Physical Activity, Diet
- Nutritional Studies and Diet
- Nutrition, Health and Food Behavior
- Cardiovascular Disease and Adiposity
- Diet and metabolism studies
- Alcohol Consumption and Health Effects
- Adipose Tissue and Metabolism
- Cancer Risks and Factors
- Cardiovascular Health and Disease Prevention
- Liver Disease and Transplantation
- Lipid metabolism and disorders
- Body Composition Measurement Techniques
- Work-Family Balance Challenges
- Adipokines, Inflammation, and Metabolic Diseases
- Physical Activity and Health
- Technology and Data Analysis
- Obstructive Sleep Apnea Research
Kangbuk Samsung Hospital
2014-2023
Sungkyunkwan University
2014-2023
Samsung (South Korea)
2023
Cohort (United Kingdom)
2017
Total (Germany)
2017
Asan Medical Center
2013-2016
University of Ulsan
2013-2016
Ulsan College
2013-2016
Johns Hopkins University
2015
University of Malaya
2015
The risk of nonalcoholic fatty liver disease (NAFLD) among obese individuals without obesity-related metabolic abnormalities, a condition referred to as metabolically healthy (MHO), is largely unexplored. Therefore, we examined the association between body mass index (BMI) categories and development NAFLD in large cohort men women.A study was conducted 77,425 women free abnormalities at baseline, who were followed-up annually or biennially for an average 4.5 years. Being defined not having...
Sarcopenia or low muscle mass is related to cardiovascular risk factors; however, the association between and subclinical atherosclerosis has been largely unexplored. We investigated whether coronary artery calcification (CAC) in a large sample of middle-aged asymptomatic adults.We performed cross-sectional study 31 108 adults without cancer, diabetes mellitus, known disease who underwent health checkup examination including cardiac tomography estimation CAC scores 2012 2013. Skeletal index...
Short and long sleep duration are associated with increased risk of clinical cardiovascular events, but the association between subclinical disease is not well established. We examined quality coronary artery calcification (CAC) brachial-ankle pulse wave velocity (PWV) in a large sample young middle-aged asymptomatic adults. conducted cross-sectional study adult men women who underwent health checkup examination, including assessment coupled either CAC (n=29 203) or PWV (n=18 106). The...
Summary Previous studies have reported a relationship between short sleep duration and childhood overweight. Although school‐aged children tend to compensate for weekday deficit by increasing weekend duration, the association catch‐up overweight remains unclear. This study aimed examine being in children. A total of 936 school (48.2% boys) aged 10 or 11 years participated this school‐based cohort study. Anthropometric measurements including height body weight were carried out. We obtained...
The effect of sarcopenic visceral obesity on the risk nonalcoholic fatty liver disease (NAFLD) is uncertain. We investigated (a) whether skeletal muscle mass to fat area ratio (SV ratio), as a measure obesity, factor for NAFLD; and (b) SV adds conventional adiposity measures improve prediction incident NAFLD. Adults without NAFLD (n = 151,017) were followed up median 3.7 years. Hepatic steatosis was measured using ultrasonography, fibrosis scores estimated Fibrosis-4 index (FIB-4) Fibrosis...
This study aimed to examine the association between glycohemoglobin (A1C) and coronary artery calcification (CAC) in nondiabetic men women without overt cardiovascular disease or diabetes mellitus after accounting for fasting glucose traditional risk factors.A cross-sectional was performed 25,564 Korean adults (41.4 ± 7.0 years) with no (fasting glucose, ≥ mmol/L a history of mellitus) clinically evident disease, who underwent health checkup, including cardiac computed tomography estimation...
Nonalcoholic fatty liver disease (NAFLD) and gallstone (GD) are often found to coexist but the sequential relationship of NAFLD GD each other remains controversial. We prospectively evaluated bidirectional with GD. A cohort study was performed on Korean adults who underwent a health checkup were followed annually or biennially for mean 6.0 years. Fatty gallstones diagnosed by ultrasound. defined as hepatic steatosis ultrasonography in absence excessive alcohol use identifiable causes. The...
Objective The aim of this study was to examine an impact body mass index (BMI) and weight change on the risk diabetes according metabolic health status. Methods Cohort 34,999 Korean men women 30‐59 years age free at baseline were followed‐up annually or biennially for average 5.1 years. Being metabolically healthy defined as not having any syndrome component. Results During 176,878.6 person‐years follow‐up, 889 participants developed (incidence rate 5.0 per 1000 person‐years). Compared...
Metabolically healthy obese (MHO) states exist that seem to be protected from cardiovascular risks. Although obesity is a risk factor for colorectal adenoma (CRA), there has yet any study of the risks CRA in MHO individuals. In this study, we compared prevalence individuals versus metabolically who were normal weight. This cross-sectional involved 18,085 Korean adults (39.1 ± 6.7 years) had health checkup including colonoscopy. High-risk was defined as over 1 cm, 3 or more adenomas, with...
It is unknown whether changes in sleep duration are associated with hypertension risk. The aim of this study was to investigate were subsequent risk developing young and middle-aged women men. We analyzed data from 106385 participants who free cardiovascular disease during the exposure period underwent a health checkup exam, including repeated measures duration. Over 250907.5 person-years, we documented 4750 incident cases hypertension. Both decrease persistently short an elevated 2.4 years....
It is unclear whether sleep duration and quality are associated with chronic kidney disease (CKD) glomerular hyperfiltration. The aim of this study was to examine the association CKD hyperfiltration in young middle-aged adults.We conducted a cross-sectional men women who underwent health checkup examination, including assessment (n = 241,607). Chronic defined as an estimated filtration rate (eGFR) less than 60 ml/min/1.73 m2, eGFR above age-/sex-specific 95th percentile.In multinomial...
Objective We evaluated the relationship between intraocular pressure (IOP) and risk of coronary artery calcification as a predictable marker cardiovascular disease (CVD) in large study asymptomatic men women. Methods A cross-sectional was performed 10 732 women without diagnosed CVD or glaucoma. Coronary calcium (CAC) measured by cardiac CT. The IOPs all participants were experienced nurses with non-contact tonometer automatic air puff control. Logistic regression used to estimate OR (95%...
To evaluate the association between sleep duration and risk of progression to diabetes among people with prediabetes, defined by HbA1c values.We conducted a cohort study in 17 983 adults who underwent health check-up examinations, including assessments quality. Diabetes was as either ≥48 mmol/mol (6.5%), or use antidiabetic medication. Time-dependent proportional hazards models were used diabetes.During 31,582 person-years follow-up, 664 incident cases identified; incidence rate 21.0 per...
Ketonuria after Fasting may be Related to the Metabolic SuperiorityObese individuals are less able oxidize fat than non-obese individuals.Caloric reduction or fasting can detect ketonuria.We investigated differences of metabolic parameters in presence ketonuria a minimum 8 hr fast cross-sectional analysis 16,523 Koreans (6,512 women and 10,011 men).The relationship between all subjects prevalence obesity, central syndrome, obesity-related were assessed.The group had lower syndrome...