A5051939978- Liver Disease Diagnosis and Treatment
- Nuclear reactor physics and engineering
- Nuclear Materials and Properties
- Diet, Metabolism, and Disease
- Health and Wellbeing Research
- Alcohol Consumption and Health Effects
- Nuclear Physics and Applications
- Liver Disease and Transplantation
- Cardiovascular Disease and Adiposity
- Nutrition and Health in Aging
- Cardiovascular Function and Risk Factors
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Cardiac Imaging and Diagnostics
- Nutritional Studies and Diet
- Colorectal Cancer Screening and Detection
- Healthcare Education and Workforce Issues
- Thyroid Disorders and Treatments
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Diverse Approaches in Healthcare and Education Studies
- Hepatitis B Virus Studies
- Blood Pressure and Hypertension Studies
- Retinal Diseases and Treatments
- Healthcare and Venom Research
- Kidney Stones and Urolithiasis Treatments
- Heart Rate Variability and Autonomic Control
Kangbuk Samsung Hospital
2014-2024
Sungkyunkwan University
2014-2024
University of Edinburgh
2022
Korea Electric Power Corporation (South Korea)
2014-2021
Korea Hydro and Nuclear Power (Korea)
2015-2021
Konkuk University
2021
Presbyterian Medical Center
2020
Cohort (United Kingdom)
2017-2019
Kyungpook National University Hospital
2012-2019
Total (Germany)
2017-2019
Background: The risk for chronic kidney disease (CKD) among obese persons without obesity-related metabolic abnormalities, called metabolically healthy obesity, is largely unexplored. Objective: To investigate the incident CKD across categories of body mass index in a large cohort men and women. Design: Prospective study. Setting: Kangbuk Samsung Health Study, Hospital, Seoul, South Korea. Participants: 62 249 healthy, young middle-aged women or proteinuria at baseline. Measurements:...
Background & AimsAlthough coronavirus disease 2019 (COVID-19) is characterized by fever and respiratory symptoms, some patients have no or mild symptoms. Severe acute syndrome-coronavirus (SARS-CoV-2) has been detected in feces of patients. We investigated gastrointestinal symptoms shedding virus into with asymptomatic COVID-19.MethodsWe collected data from 46 (median age, 26 y; 46% men) COVID-19 (without pneumonia) prolonged SARS-CoV-2, quarantined April 4, 2020, through 24, Korea....
The risk of nonalcoholic fatty liver disease (NAFLD) among obese individuals without obesity-related metabolic abnormalities, a condition referred to as metabolically healthy (MHO), is largely unexplored. Therefore, we examined the association between body mass index (BMI) categories and development NAFLD in large cohort men women.A study was conducted 77,425 women free abnormalities at baseline, who were followed-up annually or biennially for an average 4.5 years. Being defined not having...
Recent evidence suggests that alcoholic fatty liver disease (AFLD) and non-alcoholic (NAFLD) may differentially affect risk of cardiovascular mortality. To investigate whether early due to AFLD or NAFLD have similar dissimilar effects on coronary artery atherosclerosis, we investigated the associations between calcium (CAC).A cross-sectional study was performed in 105 328 Korean adults who attended a health check-up programme. CAC score assessed using CT, daily alcohol intake recorded as...
The effect of modest alcohol consumption on fibrosis progression in the general population with nonalcoholic fatty liver disease (NAFLD) remains unclear. We examined association nonheavy worsening noninvasive indices a large‐scale, low‐risk NAFLD. A cohort study was performed 58,927 Korean adults NAFLD and low scores who were followed for median 4.9 years. Non‐, light, moderate drinkers defined as 0 g/day, 1‐9.9 10‐29.9 g/day (10‐19.9 women), respectively. Progression from to intermediate or...
Abstract Background and Aim Non‐alcoholic fatty liver disease ( NAFLD ) is getting an increasing attention for its clinical implications on cardiovascular CVD ). However, epidemiologic data are not so evident to sustain the causative association between hypertension, major cause of . Accordingly, we designed this study investigate development hypertension. Methods To assess natural course blood pressure according degree (normal, mild, moderate severe), conducted a prospective cohort 22 090 K...
OBJECTIVES: The role of smoking in the development non-alcoholic fatty liver disease (NAFLD) remains controversial. We assessed risk incident NAFLD according to status and urinary cotinine levels. METHODS: performed a cohort study 199,468 Korean adults without at baseline who were followed annually or biennially for median 4.1 years. presence was determined using ultrasound. severity fibrosis score (NFS), non-invasive marker. RESULTS: During 1,070,991 person-years follow-up, 45,409...
To evaluate the association between diabetes mellitus (DM) and development of incident hearing loss.Prospective cohort study was performed in 253 301 adults with normal tests who participated a regular health-screening exam 2002 2014. The main exposure presence DM at baseline, defined as fasting serum glucose ≥ 126 mg/dL, self-reported history or current use anti-diabetic medications. Pre-diabetes 100-125 mg/dL no medication use. Incident loss pure-tone average thresholds 0.5, 1.0 2.0 kHz >...
The association between relative muscle mass (RMM) and incidence of type 2 diabetes (T2DM) is largely unknown. We examined whether RMM predicted development T2DM in an apparently young healthy population.This cohort study was comprised 113,913 men 89,854 women, free at baseline, who underwent a health checkup examination were followed-up annually or biennially for average 2.9 years. used skeletal index (SMI) as indicator RMM. SMI (%) [total (kg)/body weight (kg)×100] estimated using...
Background: Overt and subclinical hypothyroidism are associated with higher levels of serum creatinine increased risk chronic kidney disease (CKD). The prospective association between thyroid hormones function in euthyroid individuals, however, is largely unexplored. Methods: We conducted a cohort study 104 633 South Korean men women who were free CKD proteinuria at baseline had normal hormone no history or cancer. At each annual biennial follow-up visit, thyroid-stimulating (TSH),...
Pathophysiological background in different phenotypes of nonalcoholic fatty liver disease (NAFLD) remains to be elucidated. The aim was investigate the association between fecal and blood microbiota profiles presence NAFLD obese versus lean subjects. Demographic clinical data were reviewed 268 health checkup examinees, whose samples available for analysis. diagnosed with ultrasonography, subjects further categorized as (body mass index (BMI) ≥25) or (BMI <25). Fecal communities analyzed by...
<i>Objective:</i> The aim of this study was to validate the Korean version Brief Pain Inventory (BPI-K), a pain assessment tool that has been validated in several languages. <i>Methods:</i> sample consisted 132 patients Seoul who had recurrent or metastatic cancer and expressed pain. Beck Depression (BDI-K), Eastern Cooperative Oncology Group (ECOG) performance status score, Management Index (PMI), PMI-Revised (PMI-R) were used further BPI-K. <i>Results:...
OBJECTIVES: We compared liver-related mortality by fibrosis severity between 2 types of fatty liver disease (FLD), nonalcoholic FLD (NAFLD) and alcoholic (AFLD), in a large cohort nonobese obese individuals. METHODS: A study was performed with 437,828 Korean adults who were followed up for to 14 years. Steatosis diagnosed based on ultrasonography; determined the 4 (FIB-4) score. Vital status deaths ascertained through linkage national death records. RESULTS: The prevalence NAFLD AFLD 20.9%...
Background The risk of breast cancer related to changes in density over time, including its regression and persistence, remains controversial. authors investigated the relationship between time with development premenopausal postmenopausal women. Methods current cohort study included 74,249 middle‐aged Korean women (aged ≥35 years) who were free at baseline underwent repeated screening mammograms. Mammographic was categorized according American College Radiology Breast Imaging Reporting Data...
Abstract Aims The longitudinal relationship between depression and the risk of non-alcoholic fatty liver disease is uncertain. We examined: (a) association depressive symptoms incident hepatic steatosis (HS), both with without fibrosis; (b) influence obesity on this association. Methods A cohort 142 005 Korean adults neither HS nor excessive alcohol consumption at baseline were followed for up to 8.9 years. validated Center Epidemiologic Studies-Depression score (CES-D) was assessed...
The longitudinal relationship between sleep duration, quality, and the risk of nonalcoholic fatty liver disease (NAFLD) is unknown. We aimed to examine association NAFLD development. Using Pittsburgh Sleep Quality Index, duration quality were evaluated for 143,306 NAFLD-free Korean adults with a mean age 36.6 years, who followed an average 4.0 years. Hepatic steatosis (HS) was assessed using ultrasonography fibrosis by fibrosis-4 index (FIB-4) or score. Flexible parametric proportional...
Abstract Hemorrhoidal disease is a highly prevalent anorectal condition causing substantial discomfort, disability, and decreased quality of life. Evidence on preventable risk factors for hemorrhoidal limited. We conducted cross-sectional study 194,620 healthy men women who completed health screening exam including colonoscopy in 2011–2017. evaluated potential disease, lifestyle factors, medical history, birth gastrointestinal symptoms, anthropometric measurements. The prevalence was 16.6%,...
The role of hepatitis virus infection in glucose homeostasis is uncertain. We examined the associations between B (HBV) or C (HCV) and development diabetes a cohort (N = 439,708) asymptomatic participants health screening examinations. In cross-sectional analyses, multivariable-adjusted odds ratio for prevalent comparing surface antigen (HBsAg) (+) to HBsAg (-) was 1.17 (95% CI 1.06-1.31; P 0.003). corresponding antibodies (HCV Ab) HCV Ab 1.43 1.01-2.02, 0.043). prospective hazard incident...