A5002768807- Asthma and respiratory diseases
- Rheumatoid Arthritis Research and Therapies
- Inhalation and Respiratory Drug Delivery
- Inflammatory mediators and NSAID effects
- Intensive Care Unit Cognitive Disorders
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Osteoarthritis Treatment and Mechanisms
- Sepsis Diagnosis and Treatment
- Respiratory Support and Mechanisms
- Inflammatory Myopathies and Dermatomyositis
- Autoimmune and Inflammatory Disorders Research
- Semiconductor Quantum Structures and Devices
- Eosinophilic Disorders and Syndromes
- Family and Patient Care in Intensive Care Units
- Chronic Lymphocytic Leukemia Research
- Nosocomial Infections in ICU
- Advancements in Semiconductor Devices and Circuit Design
- Pregnancy and Medication Impact
- Immune Response and Inflammation
- Extracellular vesicles in disease
- GaN-based semiconductor devices and materials
- Diverse Topics in Contemporary Research
- Pain Mechanisms and Treatments
- Dental Erosion and Treatment
- Systemic Lupus Erythematosus Research
Chosun University
2006-2025
Kyungpook National University
2016-2024
Kyung Hee University
2024
National Health Insurance Service
2019-2021
National Evidenc- based healthcare Collaborating Agency
2015-2019
International St. Mary's Hospital
2014-2017
Catholic Kwandong University
2015-2017
Dong-A University Hospital
2013
Objectives Cardiovascular disease (CVD) is a major cause of death in Korea, and studies have reported that asthma can negative impact on CVD. This study aimed to identify the association between CVD, including current status, treatment duration Korean adults.
This study aimed to estimate the incidence and clinical outcomes of sepsis in Korea from 2007 2016.Retrospective observational study.Nationwide with population-based healthcare reimbursement claims database.Using data National Health Insurance Service Korea, patients who were hospitalized a diagnosis 2016 analyzed. The was calculated using mid-year census population analyzed according year, age, sex. Elixhauser Comorbidity Index score adjust for impact comorbidities on outcome. In-hospital...
Abstract Background Chronic comorbid conditions are common in patients with sepsis and may affect the outcomes. This study aimed to evaluate prevalence outcomes of comorbidities sepsis. Methods We conducted a nationwide retrospective cohort study. Using data from National Health Insurance Service Korea. Adult (age ≥ 18 years) who were hospitalized tertiary or general hospitals diagnosis between 2011 2016 analyzed. After screening all International Classification Diseases 10th revision codes...
To evaluate the risks of overall and site-specific malignancies in Korean patients with primary Sjögren's syndrome (pSS).Using nationwide healthcare claims database, we constructed a retrospective cohort for prevalent pSS aged over 50 years. After enrollment between January 2012 December 2014, were followed until development any malignancy, or 2015. Crude incidence rates calculated, their standardized ratios (SIRs) calculated compared to those knee osteoarthritis (OA) patients.A total 6,359...
Abstract Objective To examine factors related to the use of opioids as an early treatment option for knee OA patients Methods Using Korean nationwide claim database, we selected between 2013 and 2015. Among them, without any 2 years before index date were included our study population. We analyzed their first prescriptions, including tramadol stronger opioids, at each patient. a multinomial model, identified associated with in patients. Results total 2,857,999 patients, 12.2% ( n = 348,516)...
Few nationwide population-based studies have examined the burden of asthma during pregnancy. Here, we investigated and medical treatment pregnancy requiring healthcare utilisation in South Korea.Cohort study.Nationwide insurance claims database.A total 1,306,281 pregnant women who delivered Korea 2009-2011.The prevalence exacerbation rates utilisation, prescription antiasthmatic drugs pregnancy.The was 0.43% among women. Among those with 6.9% were hospitalised treated systemic steroids...
Background To identify factors for starting biosimilar TNF inhibitors (TNFI) in patients with rheumatic diseases. Methods and finding Using a national claims database, we identified rheumatoid arthritis (RA) or ankylosing spondylitis (AS) who had used TNFIs since they were approved Korea 2004. We assessed changes the proportion of each form TNFI between 2004 2017. then selected on 2013 2017 to biosimilars. In RA (n = 4,216), biosimilars more likely be initiated clinics [odds ratio (OR) 2.54]...
The purpose of this study was to assess the correlation between sedatives and mortality in critically ill patients who required mechanical ventilation (MV) for ≥ 48 hours from 2008 2016.We conducted a nationwide retrospective cohort using population-based healthcare reimbursement claims database. Data adult (aged 18) underwent MV 2016 were identified extracted National Health Insurance Service benzodiazepine group consisted administered benzodiazepines sedation during MV. All other assigned...
To investigate the use of cyclooxygenase-2 (COX-2) inhibitors as an initial drug treatment for knee osteoarthritis (OA) patients.
We investigated the association between use of inhaled bronchodilators and risk AMI. A nested case-control study using nationwide insurance claims database was conducted. Overall, 11,054 AMI cases 47,815 matched (up to 1:5) controls were identified from 1,036,119 subjects without acute major cardiovascular events in past year. Long-acting short-acting β-agonists (LABAs SABAs) associated with increase AMI, although an corticosteroid combined a long-acting β-agonist not. muscarinic antagonists...
Objective To evaluate the nonsteroidal anti-inflammatory drugs (NSAID)-sparing effect of symptomatic slow-acting for osteoarthritis (SYSADOA) in knee (OA) patients. Methods A retrospective study was conducted on a cohort OA patients who visited single academic referral hospital from 2013 to 2014. Among all patients, NSAID users their first visit were extracted and divided into SYSADOA non-users. All observed with last visit, discontinuation, or date data collection, July 2017 (mean...
Since January 2013, a nationwide drug utilization review (DUR) system for therapeutic duplication (TD) of nonsteroidal antiinflammatory drugs (NSAIDs) has been implemented in Korea. Our objective was to perform an interrupted time series study assess changes the pattern NSAIDs use knee osteoarthritis patients after implementation regulations.We compared prescribing patterns 2012 and 2013 by means study, using Health Insurance Review Assessment Service database. TD defined as concurrent...
There have been concerns that systemic corticosteroid use is associated with pregnancy-induced hypertension (PIH) and diabetes mellitus. However, the relationship between inhaled corticosteroids (ICSs) risk of PIH has not fully examined, there was no study investigating association ICS development gestational mellitus (GDM). The aims are to determine whether ICSs during pregnancy increases GDM in women. We conducted 2 nested case-control studies utilizing nationwide insurance claims database...
Objectives: To compare healthcare utilization and medical costs between patients with seronegative (SN) seropositive (SP) rheumatoid arthritis (RA). Methods: We conducted a nationwide population study using the Korean health insurance claims database in 2016. divided RA into SN SP groups compared including medications, utilization, direct for 1 year cross-sectional analysis. Differences SPRA SNRA were assessed quantile regression model. performed longitudinal analysis data from 2012 2016 to...
The purpose of this study was to evaluate whether institutional case volume affects clinical outcomes in patients receiving mechanical ventilation for 48 hours or more.We conducted a nationwide retrospective cohort using the database Korean National Healthcare Insurance Service. Between January 2007 and December 2016, 158,712 adult were included at 55 centers Korea. Centers categorized according average annual number patients: > 500, 500 300, < 300.In-hospital mortality rates high-, medium-,...
Abstract A fixed-dose combination of inhaled corticosteroid and long-acting beta agonist (ICS/LABA) may increase the risk pneumonia in patients with chronic airway diseases including obstructive pulmonary disease asthma. Although lung deposition ICS/LABA is dependent on inhaler device inhalation technique, there have been few studies comparing for according to type used deliver real-world practice. retrospective cohort study was performed using National Health Insurance Database Korean...
Most of the neural network models for generating phase holograms developed so far are trained and validated only a single distance. Consequently, if distance is altered, performance tends to decline dramatically. To address this, we introduce novel approach called 'Propagation as Data (PaD)'. Unlike conventional methods, our proposed model does not include propagation process in network. We pre-calculate kernels use them conditioning data. Experimental results demonstrate that can...