A5082713512- Systemic Lupus Erythematosus Research
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Asthma and respiratory diseases
- Inhalation and Respiratory Drug Delivery
- Organ Transplantation Techniques and Outcomes
- Rheumatoid Arthritis Research and Therapies
- Inflammatory mediators and NSAID effects
- Cardiac, Anesthesia and Surgical Outcomes
- Osteoarthritis Treatment and Mechanisms
- Liver Disease and Transplantation
- Respiratory Support and Mechanisms
- Health Systems, Economic Evaluations, Quality of Life
- Renal Transplantation Outcomes and Treatments
- Statistical Methods and Inference
- Statistical Methods and Bayesian Inference
- Hip and Femur Fractures
- Cardiac Valve Diseases and Treatments
- Monoclonal and Polyclonal Antibodies Research
- Systemic Sclerosis and Related Diseases
- Inflammatory Myopathies and Dermatomyositis
- Organ Donation and Transplantation
- Education and Learning Interventions
- Transplantation: Methods and Outcomes
- Primary Care and Health Outcomes
- Bayesian Methods and Mixture Models
Andong National University
2015-2024
Pohang University of Science and Technology
2023
Korea University
2022
Chung-Ang University
2021
Hanyang University Seoul Hospital
2018-2021
Kyungpook National University
2012-2021
Seoul National University Hospital
2017-2021
New Generation University College
2020-2021
Seoul National University
2020-2021
National Evidenc- based healthcare Collaborating Agency
2011-2019
<h3>Background</h3> Inhaled corticosteroid (ICS) use could decrease local immunity of the lung. Concerns have been raised regarding risk tuberculosis (TB) development among ICS users. The aim this study was to elucidate association between and TB patients with various respiratory diseases in South Korea, an intermediate-TB-burden country. <h3>Methods</h3> A nested case-control based on Korean national claims database performed. eligible cohort consisted 853 439 new adult users inhaled...
Aims/Introduction This study aimed to estimate the prevalence of gestational diabetes mellitus (GDM) and use anti-diabetic medications for patients with GDM in Korea, using data period 2007–2011 from Health Insurance Review Assessment (HIRA) database, which includes claims 97% Korean population. Materials Methods We used Healthcare Common Procedure Coding System codes provided by HIRA identify women delivery database between 2009 2011. was defined according ICD-10 codes, pre-existing January...
Background. The relationship between institutional case volume and clinical outcomes after living donor liver transplantation is not clarified. Methods. We conducted a nationwide retrospective cohort study using the database of Korean National Healthcare Insurance Service. Between January 2007 December 2016, 7073 adult transplantations were performed at 50 centers in Korea. Centers categorized according to average annual number transplantations: >50, 10 50, <10. Results. In-hospital...
We analyzed national data collected by the Health Insurance Review and Assessment Service in Korea from 2007 to 2011; 1) document procedural numbers rate of bipolar hemiarthroplasty (BH), primary revision total hip arthroplasties (THAs), 2) stratify prevalence each procedure age, gender, hospital type, quantified, 3) estimate burden evaluate whether is changed over time. Our final study population included 60,230 BHs, 40,760 THAs, 10,341 THAs. From 2011, both number THAs increased steadily,...
To evaluate the treatment patterns of knee osteoarthritis (OA) patients in South Korea.Using Korean nationwide claims database, all OA Korea during 2014 were identified by diagnostic code (M17) or any (M15 to M19) combination with a procedure for X-ray. Patterns medications such as nonsteroidal anti-inflammatory drugs (NSAIDs), corticosteroids (CSs), analgesics, and symptomatic slow acting (SYSADOA) analyzed. Prevalence characteristics who received CS intra-articular injection (IAI) also...
Asian-specific prediction models for estimating individual risk of osteoporotic fractures are rare. We developed a Korean fracture model using clinical factors and assessed validity the final model.A total 718,306 men women aged 50-90 years were followed 7 in national system-based cohort study. In total, 50% subjects assigned randomly to development dataset validation dataset. Clinical at biennial health check. Data on during follow-up period identified by ICD-10 codes nationwide database...
This study aimed to estimate the incidence and prevalence of idiopathic inflammatory myopathies (IIM) associated comorbidities in Korea from 2006 2015.IIM between 2004 2015 were identified using Korean National Health Insurance Service medical claim database. The case definition required more than one visit based on diagnostic codes including juvenile dermatomyositis (JDM), (DM), or polymyositis (PM) registration Individual Copayment Beneficiaries Program (ICBP) for rare intractable...
The objective of this study was to establish the efficacy and safety procalcitonin (PCT)-guided antibiotic discontinuation in critically ill patients with sepsis a country high prevalence antimicrobial resistance national health insurance system.In multi-center randomized controlled trial, were randomly assigned PCT group (stopping antibiotics based on predefined cut-off range PCT) or control group. primary end-point duration. We also performed cost-minimization analysis PCT-guided...
Interest in penicillin-binding proteins and β-lactamases (the PBP-βL family) is increasing owing to their biological clinical significance. In this study, the crystal structure of Est-Y29, a metagenomic homologue family, was determined at 1.7 Å resolution. addition, complex structures Est-Y29 with 4-nitrophenyl phosphate (4NP) diethyl phosphonate (DEP) 2.0 resolution were also elucidated. Structural analyses showed that composed two domains: β-lactamase fold an insertion domain. A deep...
This study aimed to estimate the incidence and clinical outcomes of sepsis in Korea from 2007 2016.Retrospective observational study.Nationwide with population-based healthcare reimbursement claims database.Using data National Health Insurance Service Korea, patients who were hospitalized a diagnosis 2016 analyzed. The was calculated using mid-year census population analyzed according year, age, sex. Elixhauser Comorbidity Index score adjust for impact comorbidities on outcome. In-hospital...
We compared the 3-year outcomes with regard to efficacy, stability, and safety of LASIK surface ablation performed at multiple centers in Korea.The charts 5109 eyes that underwent or ablation, including LASEK, epi-LASIK, photorefractive keratectomy (PRK), between 2002 2005 were reviewed. Of these, 577 LASIK-treated propensity score-matched surface-ablated included this cohort study. A standardized case report form (CRF) was completed based on a review follow-up chart. The CRF preoperative,...
To identify the effects of glucocorticoids (GC) on various types fractures in patients with rheumatoid arthritis (RA).We used Korean National Healthcare Claims database from 2010 to establish a retrospective cohort RA ≥ 19 years old. We then followed those through December 2013. The incidence rates total and major were calculated. evaluated GC dose duration using multivariable logistic regression analyses. also examined influence without history osteoporosis.A 11,599 was observed 9964 out...
Rationale: Current guidelines recommend that all patients undergoing treatment with a tumor necrosis factor-α antagonist should receive screening for latent tuberculosis and appropriate before initiating the inhibitor. However, no well-designed study has shown efficacy of treating these tuberculosis.Objectives: To compare risk active between factor users who have received those not.Methods: We performed national-level retrospective cohort in South Korea, country an intermediate burden, by...