A5101452838- Head and Neck Cancer Studies
- Salivary Gland Tumors Diagnosis and Treatment
- Head and Neck Surgical Oncology
- Ear and Head Tumors
- Cancer Diagnosis and Treatment
- Reconstructive Surgery and Microvascular Techniques
- Radiomics and Machine Learning in Medical Imaging
- Tumors and Oncological Cases
- Medical Imaging Techniques and Applications
- Thyroid Cancer Diagnosis and Treatment
- Tracheal and airway disorders
- Oral and Maxillofacial Pathology
- Lung Cancer Diagnosis and Treatment
- Head and Neck Anomalies
- Thyroid and Parathyroid Surgery
- Reconstructive Facial Surgery Techniques
- Cleft Lip and Palate Research
- Lymphoma Diagnosis and Treatment
- Meningioma and schwannoma management
- Vascular Tumors and Angiosarcomas
- Epigenetics and DNA Methylation
- Lung Cancer Treatments and Mutations
- Lymphatic System and Diseases
- Vascular Malformations and Hemangiomas
- Sarcoma Diagnosis and Treatment
Sungkyunkwan University
2016-2025
Kangbuk Samsung Hospital
2023-2025
Samsung Medical Center
2014-2023
Northwell Health
2023
Phelps Hospital
2023
Yonsei Sarang Hospital
2017-2018
Cyber University of Korea
2017
Yonsei University
2017
Samsung (South Korea)
2011
Korea Institute of Radiological and Medical Sciences
2009
Abstract Purpose: This study aimed to investigate whether metabolic tumor volume (MTV) measured from [18F]-fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) predicts short-term outcome radiotherapy with or without chemotherapy and disease-free survival (DFS) in patients pharyngeal cancers. Experimental Design: The MTVs of primary sites neck nodes were 82 patients. Short-term was assessed using the treatment response evaluation by Response Evaluation Criteria...
Abstract Background The prognostic significance of volume‐based metabolic parameters measured by 18 F‐fluorodeoxyglucose positron emission tomography/CT ( F‐FDG PET/CT) is not established. We evaluated the value in patients with squamous cell carcinoma (SCC) tonsil. Methods enrolled a total 69 SCC tonsil who underwent pretreatment PET/CT. maximum standardized uptake (SUV max ), tumor volume (MTV), lesion glycolysis (TLG), and asymmetry indices (of SUV , MTV, TLG). these clinical variables...
Summary Objective To compare the diagnostic accuracy of integrated 18 F‐fluorodeoxyglucose PET/CT with ultrasonography (US) and contrast enhanced CT (CECT) alone in initial evaluation cervical lymph node levels patients papillary thyroid carcinoma. Patients measurements From July 2004 to March 2005, 26 consecutive carcinoma, confirmed by aspiration cytology analysis, underwent US, CECT PET/CT. The sensitivity, specificity studies for final status 312 (levels I–V: 260, level VI: 52) were...
A phase I dose-escalation clinical trial of peritumoral injections interleukin 12 (IL-12)-transduced autologous fibroblasts was performed in patients with disseminated cancer for whom effective treatment does not exist. The goals this study were to assess the safety and toxicities as well efficacy, ancillarily immunomodulatory effects, IL-12 gene transfer. Primary dermal cultured from transduced retroviral vector carrying human genes (p35 p40) neomycin phosphotransferase (TFG-hIL-12-Neo)....
Purpose This study evaluated prospectively the value of integrated whole-body positron emission tomography and computed (PET/CT) using [ 18 F] fluorodeoxyglucose (FDG) in detecting a second primary cancer at time initial staging comparison with conventional work-up (CSW). Methods The participants were 547 patients diagnosed who underwent FDG PET/CT imaging for staging. An additional diagnostic evaluation was performed when there abnormal findings indicative on either or CSW considering site...
The role of 18F-FDG PET/CT for planning the treatment high-grade salivary gland malignancies was investigated and compared with that using contrast-enhanced CT.The subjects chosen study had cancer gland, as confirmed by surgical pathology. diagnostic values from 37 CT scans 33 were compared. ability to predict extent disease performing a subsite-based analysis primary lesions level-by-level neck node levels well final TNM staging. pathology (67.6%) clinical follow-up examinations (32.4%)...
The reported incidence of facial weakness immediately after parotid tumor surgery ranges from 14 to 65%. purpose this study was evaluate the postoperative related parotidectomy with use preoperative computed tomography (CT), intraoperative nerve monitoring, and surgical magnification. Also, we sought elucidate additional information about risk factors for in surgery, particularly focusing on subsites.We retrospectively reviewed 794 cases benign malignant tumors arising gland (2009-2016)....
Abstract Background: Despite its well‐established usefulness in the diagnosis of cervical tuberculous lymphadenitis, fine‐needle aspiration cytology (FNAC) has several limitations clinical applications, especially when presence acid‐fast bacilli is not proven. Furthermore, aspirate sometimes inadequate for diagnosis, and sensitivity specificity this technique lymphadenitis been firmly established. Objective: The authors performed Mycobacterium tuberculosis polymerase chain reaction (PCR)...
Background: This study evaluates the impact of three-dimensional (3D) printing-guided maxillectomy compared with conventional on surgical precision and oncological outcomes in patients head neck cancer. Materials Methods: A retrospective analysis was conducted 42 undergoing (16 a 3D group 26 group). Patient demographics, tumor characteristics, were compared. Survival analyzed using Kaplan–Meier method. Results: The printing showed higher rates negative resection margins (81.3% vs. 76.9%)...
Objective: To evaluate the prognostic value of volume-based metabolic parameters measured with 18 F-fluorodeoxyglucose ( F-FDG) positron emission tomography (PET) in patients clinically node-negative (cN0) oral tongue squamous cell carcinoma (OTSCC) as compared other factors.Materials and Methods: In this study, we included a total 57 who had been diagnosed cN0 cancer by radiologic, F-FDG PET/CT, physical examinations.The maximum standardized uptake (SUV max ), average SUV avg tumor volume...
Salivary duct carcinoma (SDC) is a highly aggressive subtype of salivary gland cancers and there no established standard therapy for this disease. Thus, development molecular markers SDC will be important to guide the diagnosis tumor. We performed next-generation sequencing using Ion Torrent AmpliSeq cancer panel, which explores mutational status hotspot regions in 50 cancer-associated genes, we analyzed copy number variations (CNVs) 21 genes by NanoString nCounter 37 patients with SDC....
High-grade salivary gland cancer is a distinct clinical entity that has aggressive disease progression and early systemic spread. However, because of the rarity disease, outcomes, prognostic factors decision on optimal treatments have not been fully understood.In this study, we retrospectively analyzed data 124 patients with high-grade cancers performed multivariate survival analyses to evaluate clinico-pathological affecting treatment outcomes.The 5-year disease-specific was 63.4% in...
This study evaluated the feasibility of endoscopic-assisted extracapsular dissection benign parotid tumors using only hairline incision.Endoscope-assisted via incision was performed in 18 cases (5 men and 13 women) gland tumor (pleomorphic adenoma 4 cases, Warthin's 14 cases).All operations were successfully no conversions to conventional open resection necessary. One patient had transient facial paresis recovered within 1 month. The duration procedure 82.5 ± 18.5 minutes.Endoscope-assisted...
Conclusions. For extracranial arteriovenous malformations of the head and neck (HNAVMs), in which nidus was accessible via percutaneous route, ethanol sclerotherapy a feasible safe first-line treatment, although successful outcomes were obtained for only about half subjects. other HNAVMs, surgical excision with embolization may be best choice treatment. Objective. To suggest treatment protocol patients HNAVMs by comparing complications those combined embolization. Material methods. Twenty...
To investigate the clinical usefulness of intraoral sonography-assisted resection for securing adequate deep margins in T1-2 tongue cancers.Prospective trial.Twenty consecutive patients with cancers were enrolled and their lesions removed by resection. We then retrospectively collected data from 20 T stage-matched without as control group. All resections performed a goal 15 mm margin. The mucosal safety compared between two groups.Intraoral sonography could predict paraffin-embedded tumor...
Objectives Malalignment of the tibial component could influence long-term survival a total knee arthroplasty (TKA). The object this study was to investigate biomechanical effect varus and valgus malalignment on under stance-phase gait cycle loading conditions. Methods Validated finite element models for by 3° 5° were developed evaluate in TKA. Maximum contact stress area polyethylene insert, maximum patellar button collateral ligament force investigated. Results There greater alignment than...