A5017419314- Cardiovascular Function and Risk Factors
- Cardiac Valve Diseases and Treatments
- Cardiac Imaging and Diagnostics
- Infective Endocarditis Diagnosis and Management
- Atrial Fibrillation Management and Outcomes
- Cardiac Structural Anomalies and Repair
- Cardiovascular Health and Disease Prevention
- Cardiac Arrhythmias and Treatments
- Cardiomyopathy and Myosin Studies
- Cardiovascular Effects of Exercise
- Cardiovascular Disease and Adiposity
- Cardiac pacing and defibrillation studies
- Aortic Disease and Treatment Approaches
- Congenital Heart Disease Studies
- Cardiac tumors and thrombi
- Pericarditis and Cardiac Tamponade
- Pulmonary Hypertension Research and Treatments
- Cardiovascular and Diving-Related Complications
- Blood Pressure and Hypertension Studies
- Heart Failure Treatment and Management
- Lipoproteins and Cardiovascular Health
- Cerebrovascular and Carotid Artery Diseases
- Heart Rate Variability and Autonomic Control
- Aortic aneurysm repair treatments
- Advanced MRI Techniques and Applications
Yonsei University
2016-2025
Gangnam Severance Hospital
2014-2024
Severance Hospital
2015-2024
Myongji Hospital
2024
Yonsei University Health System
2011-2023
Tzu Chi University
2021
University Health System
2011-2020
Keimyung University
2018
Keimyung University Dongsan Medical Center
2018
National Institutes of Health
2018
To assess the diagnostic accuracy of two-phase 64-section cardiac computed tomographic (CT) angiography for detection left atrial appendage (LAA) thrombi and differentiation between thrombus circulatory stasis in patients with stroke, transesophageal echocardiography (TEE) as reference standard.This study was institutional review board approved, all gave written informed consent. Fifty-five consecutive (36 men, 19 women; mean age, 61 years) who had recently experienced a high-risk factors...
Left atrial (LA) fibrosis is a main determinant of LA remodeling and development fibrillation. However, non-invasive prediction challenging. We investigated whether preoperative strain as measured by speckle tracking echocardiography could predict the degree reverse after mitral valve (MV) surgery.Speckle volume measurements were performed in 50 patients one day before MV surgery. tissues obtained during surgery, degrees their interstitial fibroses measured. repeated within 30 days surgery...
Background— Recent evolution of cardiac computed tomography (CT) provides useful information about valvular and perivalvular structures. We compared the diagnostic performance CT transesophageal echocardiography (TEE) with applications 3-dimensional reconstruction in detecting vegetation intracardiac complications patients infective endocarditis (IE). Methods Results— Seventy-five (53 men; age, 58±15 years) definite IE who underwent TEE within 3 days were analyzed. The performances 2...
Abstract Mesenchymal stem cell (MSC) therapy for myocardial injury has inherent limitations due to the poor viability of MSCs after transplantation. In this study, we directly delivered Hsp70, a protein with protective functions against stress, into MSCs, using Hph-1 transduction domain ex vivo high transfection efficiency and low cytotoxicity. Compared control in vitro hypoxic conditions, Hph-1-Hsp70 (Hph-1-Hsp70-MSCs) displayed higher anti-apoptotic properties, including Bcl2 increase,...
AimsHigh calcium (Ca), phosphate (P), and Ca–P product (CPP) are associated with cardiovascular disease in patients chronic kidney disease. Whether this relationship persists individuals normal function is not yet elucidated. We explored the of serum Ca, P, CPP to coronary atherosclerosis assessed by cardiac computed tomography angiography (cCTA) participants function.
<h3>Objective</h3> To investigate clinical outcomes of exercise-induced pulmonary hypertension (PH) and implications an increase in left ventricular (LV) filling pressure during exercise subjects with preserved LV ejection fraction. <h3>Design</h3> Longitudinal follow-up study. <h3>Setting</h3> Subjects who were referred for diastolic stress echocardiography. <h3>Patients methods</h3> The ratio transmitral annular velocities (E/Ea) artery systolic (PASP) at rest measured 498 (57±11 years;...
Abstract MicroRNA-206, which suppresses the expression of brain-derived neurotrophic factor, is known to be elevated in brains Alzheimer’s disease (AD) patients. We performed intranasal biopsy olfactory epithelia early dementia patients (n = 24) and cognitively healthy controls 9). Patients with significant depression 8) were analyzed separately, as their cognitive impairments thought caused by depression. Real-time PCR was on biopsied tissues. The relative microRNA-206 level exhibited a...
Objectives Malignant pericardial effusion (MPE) in patients with cancer is associated poor prognosis. This study aimed to compare clinical outcomes who underwent pericardiocentesis versus window formation. Methods In the present study, 765 consecutive (mean age 58.4 years, 395 men) drainage between 2003 and 2022 were retrospectively analysed. All-cause death MPE recurrence compared based on method (pericardiocentesis vs formation) time period (period 1: 2003–2012; 2: 2013–2022). Results...
Abstract Autologous mesenchymal stem cell (MSC) transplantation therapy for repair of myocardial injury has inherent limitations due to the poor viability cells after transplantation. Adhesion is a prerequisite survival and also key factor differentiation MSCs. As novel prosurvival modification strategy, we genetically engineered MSCs overexpress tissue transglutaminase (tTG), with intention enhance adhesion ultimately implantation. tTG-transfected (tTG-MSCs) showed 2.7-fold greater than...
To evaluate the clinical feasibility and accuracy of 64-section multidetector computed tomography (CT) compared with transesophageal echocardiography (TEE) for diagnosis a patent foramen ovale (PFO).Institutional review board approval was obtained this retrospective study. The study included 152 consecutive stroke patients (mean age, 61.7 years; 98 men, 54 women) who underwent both cardiac CT TEE. Electrocardiographically gated performed scanner by using saline-chaser contrast agent...
We assessed the diagnostic performance of 2-phase 64-slice cardiac computed tomographic angiography (CCTA) for detection a source embolism in stroke patients using transesophageal echocardiography (TEE) as reference standard.We selected 137 who had experienced recent episode and undergone both CCTA TEE within period 5 days. A potential detected at was recorded, echocardiographic findings were categorized into high- medium-risk sources based on TOAST (Trial Org 10172 Acute Stroke Treatment)...
The aim of this study is to explore the differential effect 3-dimensional color Doppler echocardiography for quantification mitral regurgitation (MR). Two-dimensional echocardiography-based MR has well-documented limitations.We consecutively enrolled 221 patients with MR. Adequate image quality was obtained by 2D- and 3D-color in 211 (95.5%) patients. quantitative differences between volumes 3D-proximal isovelocity surface area (PISA) were analyzed various subgroups. In validation cohort...