A5035835774- Acute Myocardial Infarction Research
- Antiplatelet Therapy and Cardiovascular Diseases
- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Marine Bivalve and Aquaculture Studies
- Cardiovascular Function and Risk Factors
- Parasite Biology and Host Interactions
- Venous Thromboembolism Diagnosis and Management
- Atrial Fibrillation Management and Outcomes
- Heart Failure Treatment and Management
- Cardiac Valve Diseases and Treatments
- Marine Biology and Environmental Chemistry
- Blood Pressure and Hypertension Studies
- Cardiac pacing and defibrillation studies
- Coronary Artery Anomalies
- Aquatic Invertebrate Ecology and Behavior
- Lipoproteins and Cardiovascular Health
- Cardiac electrophysiology and arrhythmias
- Vibrio bacteria research studies
- Aortic Disease and Treatment Approaches
- Kawasaki Disease and Coronary Complications
- Cardiac Arrest and Resuscitation
- Aquaculture disease management and microbiota
- Vascular anomalies and interventions
- Cardiac Structural Anomalies and Repair
Seoul National University
2010-2024
Seoul National University Hospital
2010-2024
Dong-A University Hospital
2015-2024
Dong-A University
2014-2024
New Generation University College
2024
Inha University Hospital
2023
Kunsan National University
2012-2022
University Medical Center
2020
University Hospital and Clinics
2020
Keimyung University
2012-2017
We evaluated the prognosis of deferred and revascularized coronary stenoses after fractional flow reserve (FFR) measurement to assess its revascularization threshold in clinical practice.The IRIS-FFR registry (Interventional Cardiology Research In-cooperation Society Fractional Flow Reserve) prospectively enrolled 5846 patients with ≥1coronary lesion FFR measurement. Revascularization was 6468 lesions performed 2165 assessment. The primary end point major adverse cardiac events (cardiac...
To limit compromising the integrity of planet, a shift is needed towards food production with low environmental impacts and carbon footprint. How to put such transformative change sustainable whilst ensuring security into practice remains challenge will require transdisciplinary approaches. Combining expertise from natural- social sciences as well industry perspectives, an alternative vision for future in marine realm proposed. This includes moving aquaculture mainly trophic (LTM) species....
Limited data are available on short-term dual antiplatelet therapy (DAPT) after percutaneous coronary intervention using third-generation drug-eluting stents with ultrathin struts and advanced polymer technology. We investigated whether 3- to 6-month DAPT was noninferior 12-month implantation of technology.We performed an open-label, randomized trial at 37 centers in South Korea. enrolled patients undergoing the Orsiro biodegradable-polymer sirolimus-eluting or Coroflex ISAR polymer-free...
Background: Large-scale randomized comparison of drug-eluting stents (DES) based on durable polymer versus biodegradable technology is currently insufficient in patients with acute coronary syndrome (ACS). The present study aimed to prove the noninferiority DES (DP-DES) compared (BP-DES) such patients. Methods: HOST-REDUCE-POLYTECH-ACS (Harmonizing Optimal Strategy for Treatment Coronary Artery Diseases—Comparison Reduction Prasugrel Dose or Polymer Technology ACS Patients) trial an...
Despite recent successful efforts to shorten the door-to-balloon time in patients with acute ST-segment elevation myocardial infarction (STEMI), prehospital delay remains unaffected.Nonetheless, factors associated have not been clearly identified Korea.We retrospectively evaluated 423 STEMI.The mean symptom onset-to-door was 255 ± 285 (median: 150) min.The were analyzed two groups according (short group: ≤ 180 min vs long > min).Inhospital mortality significantly higher group (6.9% 2.8%; P =...
To examine physiological and clinical relevance of an anomalous right coronary artery originating from left sinus Valsalva (right ACAOS) with interarterial course in adults.For assessment, fractional flow reserve (FFR) during dobutamine challenge was measured 37 consecutive adult patients lone ACAOS course. At baseline, mean FFR 0.91±0.06, declining to 0.89±0.06 upon infusion (p<0.001). Dobutamine stress significant (≤0.8) three (8.1%), two whom were surgically treated. Following surgery,...
Over the past few decades, mass mortality events of Manila clams have been reported from several tidal flats on west coast Korea during hot summers. During such events, once simultaneously surface, they fail to re-burrow, perishing within a week. The present study aimed identify possible causes this clam species by investigating Perkinsus olseni parasite burden and immune parameters surfaced (SC) normal buried (NBCs) when sea water or sediment temperature in area varied 25 °C 34 late July...
De-escalation of dual-antiplatelet therapy through dose reduction prasugrel improved net adverse clinical events after acute coronary syndrome (ACS), mainly the bleeding without an increase in ischemic outcomes. However, whether such benefits are similarly observed those receiving complex procedures is unknown.To investigate de-escalation maintained percutaneous intervention (PCI) subgroup.This was a post hoc analysis HOST-REDUCE-POLYTECH-ACS trial, randomized, open-label,...
Background: Ticagrelor reduced the rate of myocardial infarction and death compared with clopidogrel in patients acute coronary syndrome. However, little is understood about chronic treatment ticagrelor on microvascular dysfunction. The objective this study was to assess impact maintenance system flow comparison clopidogrel. Methods: This a nonblinded, open-label, parallel-group, prospective, randomized controlled trial that enrolled 120 syndrome requiring stent implantation. Patients were...
Individuals with intermediate to high cardiac risk for major noncardiac surgery suffer from perioperative myocardial ischemic injury. The purpose of this study was evaluate the long-term impact postoperative troponin elevation on clinical outcome after surgery.Patients (n = 750) aged ≥ 50 years who underwent were eligible study. Postoperative troponin-I data collected retrospectively and consecutively. primary measure allcause mortality. median follow-up period 1727 days in all...
Background:There is insufficient data on the efficacy of prasugrel and ticagrelor in Korean patients with ST-segment elevation myocardial infarction (STEMI).Methods Results:In current double-blind, prospective pilot study, 39 STEMI undergoing primary percutaneous coronary intervention were randomized to receive 60 mg loading dose (LD) followed by 10 daily maintenance (n=19), or 180 LD 90 twice (n=20). We assessed platelet reactivity VerifyNow Vasodilator-Stimulated Phosphoprotein (VASP)...
High quality integrated post-cardiac arrest care can significantly influence the outcome of patients with cardiac arrest, especially neurological recovery, and numerous studies have been conducted on this topic.In 2015 Korean cardiopulmonary resuscitation (CPR) guidelines, was emphasized effective advanced life support as one essential chains for survival.Based an in-depth scientific evidence review using a standardized methodological approach proposed by GRADE (Grading Recommendations...
The differential diagnosis of cardiac mass is important in determining the therapeutic plan and avoiding unnecessary surgical intervention. Non-invasive imaging methods would be useful suspected mass, because they may provide earlier more accurate assessment mass. Native aortic valve thrombosis a rare disorder difficult to differentiate from tumor, particular, papillary fibroelastoma. Thus, clinical decision making with modalities should performed cautiously. We recently met female patient...
Abstract Streptococcus iniae is a causative agent of hemorrhagic septicemia in olive flounder, Paralichthys olivaceus , Korea, resulting serious economic losses. As preventive measure, M VAC INIAE (Mastuken, Japan) was prepared from the S. F2K strain and tested against SI-36 prevalent on flounder fish farms Jeju Island, Korea. had serotype 38 (−) (+). The vaccine recognized both serotypes. It showed very high effective immune response ; challenge test using resulted relative percent survival...
Background— The paclitaxel-eluting stent (PES) and sirolimus-eluting (SES) are first-generation drug-eluting stents (DES) that have been the most widely used; however, it is unclear whether there differences in long-term safety efficacy between 2 stents. effectiveness of DES unselected people with diabetes also currently unclear. Moreover, possibility late catch-up suggested population. Methods Results— This study an 8-center collaborative network analysis all comers who received SES PES....